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Keywords: endothelin receptor antagonism
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Articles
Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension
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Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 25S–30S.
Published: 01 September 2002
.... INTRODUCTION Aldosterone-induced hypertension is associated with vascular remodelling and cardiac fibrosis [1 3], which have been attributable, in part, to the action of endothelin-1 (ET-1) [1,4]. Recent evidence suggests that aldosterone is also an important factor in causing Key words : endothelin receptor...