... [email protected] ). 13 11 2008 27 11 2008 27 11 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 chronic obstructive pulmonary disease (COPD) dyspnoea endothelin-1 (ET-1) exercise capacity pulmonary hypertension statin However...

... disease (COPD) dyspnoea endothelin-1 (ET-1) exercise capacity pulmonary hypertension statin Pulmonary function indices at baseline and at the end of the study were performed according to American Thoracic Society standards [ 11 ]. We used an FEV 1 /FVC ratio of <0.70 to define...

... Biosciences) from 0–10 μmol/l in DMEM containing 2.5% (v/v) FCS for various lengths of time [24 h for RT-PCR (reverse transcription–PCR), Northern blotting and Western blotting, and 5 min, 30 min and 4 h for NF-κB (nuclear factor κB) determination]. endothelin-1 (ET-1) ET A gelatinase nuclear factor...

... to be normotensive if their blood pressure was <140/90 mmHg. None of the control patients had proteinuria. arterial pressure endothelin-1 (ET-1) pre-eclampsia pregnancy uterus Pre-eclampsia, a disorder unique to pregnancy, is one of the leading causes of maternal and fetal mortality...

... of endothelin-1 (ET-1), a potent vasoconstictor, by the endothelium. However, there is profound vasodilatation in sepsis, where circulating levels of both ET-1 and TNF-α are elevated. The details of the interaction between ET-1 and TNF-α and the predominant resulting haemodynamic effect in healthy humans...