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Keywords: endothelium
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Articles
Khatera Saii, Judit Prat-Duran, Ulf Simonsen, Anders Riegels Knudsen, Jonas Amstrup Funder, Niels Henrik Buus, Estéfano Pinilla
Journal:
Clinical Science
Clin Sci (Lond) (2025) 139 (1): 1–14.
Published: 15 January 2025
... whether pharmacological modulation of TG2 into its closed conformation induces vasorelaxation and enhances endothelium-dependent and independent relaxation in resistance arteries from age-matched diabetic ( n = 14) and non-diabetic patients ( n = 14) (age 71 (Standard Error of the Mean: ± 2...
Includes: Supplementary data
Articles
Kurt Brassington, Stanley M.H. Chan, Simone N. De Luca, Aleksandar Dobric, Suleman A. Almerdasi, Kevin Mou, Huei Jiunn Seow, Osezua Oseghale, Steven Bozinovski, Stavros Selemidis, Ross Vlahos
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (8): 537–555.
Published: 21 April 2022
... for the production of nitric oxide (NO) within the endothelium, was measured using a NOS3 antibody (Thermo Fisher Scientific, U.S.A., 1:100 dilution). Vascular peroxynitrite was quantified using antibody staining against 3-Nitrotyrosine (3-NT) (Thermo Fisher Scientific, 1:100 dilution), which is the product...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (12): 1487–1503.
Published: 17 June 2021
..., and the initiating mechanisms remain incompletely understood. More recently, circulating inflammatory markers, cardiac biomarkers, microRNAs, and extracellular vesicles (EVs) have been considered as early markers of cardiovascular injury. Concomitantly, the role of the endothelium in regulating cardiac function...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (11): 1055–1058.
Published: 10 May 2017
... endothelial dysfunction. Correspondence: Joel D. Trinity ( [email protected] ) 14 03 2017 10 04 2017 12 04 2017 © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017 blood flow endothelium physical inactivity shear...
Articles
Thiago Bruder-Nascimento, Simone Kennard, Galina Antonova, James D. Mintz, Kendra K. Bence, Eric J. Belin de Chantemèle
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (11): 881–893.
Published: 22 April 2016
...) as described previously [ 21 ]. Briefly, two tungsten wires were inserted into the lumen of the arteries and fixed to a force transducer and a micrometer. Arteries were bathed in a physiological salt solution and arterial viability was determined with a potassium-rich solution (40 mmol/l). Endothelium...
Includes: Supplementary data
Articles
Cindy K. Kao, Jude S. Morton, Anita L. Quon, Laura M. Reyes, Patricio Lopez-Jaramillo, Sandra T. Davidge
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (7): 539–549.
Published: 17 February 2016
... associated with this disease. circulating factors endothelium nitric oxide pre-eclamptic plasma prostaglandin uterine artery Following an overnight incubation in 3% plasma and 1 m-unit/ml of heparin, mesenteric and uterine arteries were mounted on two 40-μm wires and attached to a wire...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2015) 129 (12): 1195–1206.
Published: 11 November 2015
.... Alzheimer's disease blood–brain barrier endothelium lipids statins Therefore, we have examined the hypothesis that systemic oxLDL affects the function of microvascular endothelial cells to secrete inflammatory mediators into the brain compartment pre-disposing to AD and that statin intervention...
Includes: Supplementary data
Articles
Diana Hide, Martí Ortega-Ribera, Anabel Fernández-Iglesias, Constantino Fondevila, M. Josepa Salvadó, Lluís Arola, Juan Carlos García-Pagán, Aldo Mancini, Jaime Bosch, Jordi Gracia-Sancho
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (8): 527–537.
Published: 30 June 2014
... to characterize the effects of a new recombinant form of human manganese superoxide dismutase (rMnSOD) on hepatic CS+WR injury. After CS+WR, the liver endothelium exhibited accumulation of superoxide anion (O 2 − ) and diminished levels of nitric oxide (NO); these detrimental effects were prevented by rMnSOD. CS...
Includes: Supplementary data
Articles
Markus P. Schneider, Andreas Schneider, Agnes Jumar, Iris Kistner, Christian Ott, Roland E. Schmieder
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (7): 499–505.
Published: 17 June 2014
... ml/min per m 2 during placebo compared with −63±56 ml/min per m 2 during FA, P =0.57; ΔRPF to vitamin C: +93±118 ml/min per m 2 compared with +94±108 ml/min per m 2 ; P =0.70). In line with the lack of effect on the renal endothelium, albuminuria was not affected by FA treatment (110±179 mg/day...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (9): 579–587.
Published: 21 January 2013
...) underwent cardiopulmonary exercise tolerance test, and were assessed for their upper- and lower-limb vascular endothelial CVC (cutaneous vascular conductance) using LDF (laser Doppler fluximetry) with endothelium-dependent [ACh (acetylcholine chloride)] and -independent [SNP (sodium nitroprusside...
Articles
Ruth M. Mackenzie, Ian P. Salt, William H. Miller, Angela Logan, Hagar A. Ibrahim, Andrea Degasperi, Jane A. Dymott, Carlene A. Hamilton, Michael P. Murphy, Christian Delles, Anna F. Dominiczak
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (6): 403–411.
Published: 27 November 2012
... (coronary artery disease) and T2D (Type 2 diabetes mellitus) is concomitant with elevated mtROS (mitochondrial reactive oxygen species) production in the endothelium and establish if this, in turn, regulates the activity of endothelial AMPK (AMP-activated protein kinase). We investigated endothelial...
Includes: Supplementary data
Articles
Ilse P. G. Botden, Hisko Oeseburg, Matej Durik, Frank P. J. Leijten, Leonie C. Van Vark-Van Der Zee, Usha M. Musterd-Bhaggoe, Ingrid M. Garrelds, Ann L. B. Seynhaeve, Janneke G. Langendonk, Eric J. G. Sijbrands, A. H. Jan Danser, Anton J. M. Roks
Journal:
Clinical Science
Clin Sci (Lond) (2012) 123 (8): 499–507.
Published: 27 June 2012
... endothelium nitric oxide prostaglandin reactive oxygen species red wine polyphenol Aging is an independent and important risk factor for CVD (cardiovascular disease) [ 1 ]. Senescence of the vascular wall may be on the causal path to age-related endothelial dysfunction and atherogenesis...
Articles
Pietro Minuz, Cristiano Fava, Gaetano Vattemi, Guido Arcaro, Matteo Riccadonna, Paola Tonin, Alessandra Meneguzzi, Maurizio Degan, Valeria Guglielmi, Alessandro Lechi, Giuliano Tomelleri
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (6): 289–299.
Published: 22 November 2011
... of the respiratory chain function with altered oxidative phosphorylation. We tested the hypothesis that the function of vascular endothelium is affected by increased oxidative stress in MDs. A total of 12 patients with MDs and pair-matched controls were studied. Endothelial function was assessed by measuring FMD...
Includes: Supplementary data
Articles
Natallia Luksha, Leanid Luksha, Juan Jesús Carrero, Folke Hammarqvist, Peter Stenvinkel, Karolina Kublickiene
Journal:
Clinical Science
Clin Sci (Lond) (2011) 120 (12): 525–536.
Published: 09 March 2011
.... cardiovascular disease diabetes end-stage renal disease endothelium flow-mediated dilatation nitric oxide resistance artery Despite the rapid progress in dialysis treatment, ESRD (end-stage renal disease) patients still die at a markedly accelerated rate, principally from CVD (cardiovascular...
Articles
Elena Conti, Maria Beatrice Musumeci, Marco De Giusti, Eleonora Dito, Vittoria Mastromarino, Camillo Autore, Massimo Volpe
Journal:
Clinical Science
Clin Sci (Lond) (2011) 120 (9): 377–402.
Published: 18 January 2011
... stimulus, represented by HIF (hypoxia-inducible factor) synthesis [ 6 ]. Conversely, evidence for the stimulation of IGF-1 by other growth factors is lacking. atherothrombosis chronic renal failure diabetes endothelium insulin-like growth factor-1 (IGF-1) myocardial infarction recombinant human...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2011) 120 (4): 131–141.
Published: 02 November 2010
... in endothelial cells [ 25 ]. One possible explanation that has been suggested is that Rac1 indirectly mediates ROS production by Nox4 [ 26 ]. endothelium hydrogen peroxide NADPH oxidase (Nox) reactive oxygen species superoxide vascular smooth muscle cell ROS (reactive oxygen species...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2011) 120 (2): 51–63.
Published: 24 September 2010
.... Correspondence: Professor Massimo Volpe (email [email protected] ). 14 6 2010 19 7 2010 9 8 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 biomarker congestive heart failure (CHF) chronic renal failure (CRF) endothelium erythropoietin (EPO...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 119 (6): 225–238.
Published: 08 June 2010
... of arteriogenesis, comprising sensing of shear stress, endothelial activation and subsequent vasodilatation. Another possible sensor for shear stress is the glycocalyx. This luminal lining of the endothelium, consisting of membranous glycoproteins, proteoglycans and associated plasma proteins, was proposed...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 119 (1): 1–17.
Published: 07 April 2010
...Alyson A. Miller; Klaudia Budzyn; Christopher G. Sobey The endothelium plays a crucial role in the control of vascular homoeostasis through maintaining the synthesis of the vasoprotective molecule NO • (nitric oxide). Endothelial dysfunction of cerebral blood vessels, manifested as diminished...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 119 (1): 19–36.
Published: 07 April 2010
... [email protected] ). 7 12 2009 5 2 2010 9 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 cation channel endothelium smooth muscle transient receptor potential (TRP) channel vascular function The TRP (transient receptor potential) channel...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (10): 633–640.
Published: 23 February 2010
...Ellen A. Dawson; Sudhir Rathore; N. Timothy Cable; D. Jay Wright; John L. Morris; Daniel J. Green The aim of this study was to determine the impact of catheter sheath insertion, a model of endothelium disruption in humans, on the conventional FMD (flow-mediated dilatation) response in vivo...
Articles
Carmine Savoia, Talin Ebrahimian, Catherine A. Lemarié, Pierre Paradis, Marc Iglarz, Farhad Amiri, Danesh Javeshgani, Ernesto L. Schiffrin
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (9): 583–592.
Published: 09 February 2010
... or not with rosiglitazone (20 mg·kg −1 of body weight·day −1 ) for 90 days and compared with wild-type mice. Endothelium-dependent relaxation of carotid arteries was significantly impaired (−40%) only in rosiglitazone-treated HCD-fed mthfr +/− mice. Carotid M/L (media-to-lumen ratio) and CSA (cross-sectional area) were...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (7): 459–461.
Published: 12 January 2010
... ). 28 10 2009 2 11 2009 4 11 2009 4 11 2009 ADP angiotensin II clopidogrel endothelium hypertension mesenteric artery P2Y receptor Platelets, normally circulating in resting form, respond to vascular injury by adhering to the damaged vessel wall. Activation results...
Articles
Fernanda R. C. Giachini, David A. Osmond, Shali Zhang, Fernando S. Carneiro, Victor V. Lima, Edward W. Inscho, R. Clinton Webb, Rita C. Tostes
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (7): 463–471.
Published: 12 January 2010
... endothelium-dependent relaxation [(Emax %)=71±12%) as well as contractile vascular responses (Emax %=83±12%), these actions are not mediated by P2Y 12 receptor activation. 2-MeS-ADP produced similar vascular responses in control and AngII rats. These results indicate potential effects of clopidogrel...
Articles
Gian Paolo Fadini, Mattia Albiero, Andrea Cignarella, Chiara Bolego, Christian Pinna, Elisa Boscaro, Elisa Pagnin, Renzo De Toni, Saula De Kreutzenberg, Carlo Agostini, Angelo Avogaro
Journal:
Clinical Science
Clin Sci (Lond) (2009) 117 (10): 355–364.
Published: 07 September 2009
... use, distribution and reproduction in any medium, provided the original work is properly cited. androgen cardiovascular system endothelial progenitor cell endothelium gender oestrogen stem cell Cardiovascular risk gradients are primarily driven by gender: women of a reproductive...
Articles
Emeline M. Van Craenenbroeck, Johan Denollet, Bernard P. Paelinck, Paul Beckers, Nadine Possemiers, Vicky Y. Hoymans, Christiaan J. Vrints, Viviane M. Conraads
Journal:
Clinical Science
Clin Sci (Lond) (2009) 117 (4): 165–172.
Published: 16 July 2009
... curves permitted the researchers to encourage patients to exercise up to exhaustion. Endothelium-dependent vasodilation was assessed in supine position by ultrasound of the right brachial artery (AU5 ultrasound system; Esaote Biomedica). End-diastolic diameters were evaluated at rest and during...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2009) 117 (4): 139–155.
Published: 16 July 2009
...Michel Félétou; Paul M. Vanhoutte The endothelium controls vascular tone not only by releasing NO and prostacyclin, but also by other pathways causing hyperpolarization of the underlying smooth muscle cells. This characteristic was at the origin of the term ‘endothelium-derived hyperpolarizing...
Articles
Emily M. Segar, Andrew W. Norris, Jian-Rong Yao, Shanming Hu, Stacia L. Koppenhafer, Robert D. Roghair, Jeffrey L. Segar, Thomas D. Scholz
Journal:
Clinical Science
Clin Sci (Lond) (2009) 117 (3): 129–138.
Published: 02 July 2009
... by the trapezoidal rule, were detected. Figure 5 Aortic responsiveness in female CON offspring (●) and ODM (■) to KCl (A), 5-HT (B), NA (C), ET-1 (D) and AngII (E) in the presence or absence (rubbed) of vascular endothelium, and to NA (F) and ET-1 (G) in the presence or absence of L -NNA (A–E...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 113 (2): 47–63.
Published: 13 June 2007
... becomes enzymatically uncoupled and generates superoxide, contributing to vascular oxidative stress and endothelial dysfunction. BH4 bioavailability is determined by a balance of enzymatic de novo synthesis and recycling, versus oxidative degradation in dysfunctional endothelium. Augmenting vascular BH4...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (1): 1–25.
Published: 01 December 2006
... type and produce IL-1β and TNFα after infection or injury to the CNS. The main cellular target for IL-1β and TNFα produced in the brain (peri)vascular compartment is the endothelium, where these cytokines induce the expression of adhesion molecules and promote leucocyte infiltration. Whether...
Articles
Minami Abe, Masataka Sata, Etsu Suzuki, Ryo Takeda, Masao Takahashi, Hiroaki Nishimatsu, Daisuke Nagata, Kenji Kangawa, Hisayuki Matsuo, Ryozo Nagai, Yasunobu Hirata
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (6): 381–387.
Published: 14 November 2006
... development endothelium ischaemia AM (adrenomedullin) was isolated as a vasodilatory peptide from pheochromocytoma [ 1 ]. The major source of circulating AM is the vascular wall [ 2 – 4 ], suggesting an important role in the regulation of vascular tone. However, AM has been found to exert many other...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (1): 35–46.
Published: 14 June 2006
... existing cardiac myocytes. This process is intimately linked to the development of coronary vasculature from progenitors originating in the endothelium, the proepicardial organ and neural crest. In this review, we systematically evaluate approx. 90 mouse mutations that impair heart muscle growth during...
Articles
H. M. Omar Farouque, Michael Leung, Sarah A. Hope, Mauro Baldi, Clyde Schechter, James D. Cameron, Ian T. Meredith
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (1): 71–80.
Published: 14 June 2006
... and antiplatelet activity, immunoregulatory properties and beneficial effects on the endothelium [ 1 , 8 – 12 ]. The latter property is of potential clinical relevance, since endothelial dysfunction is an early event in the process of atherogenesis and one that may contribute to ischaemic sequelae [ 13 , 14...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (6): 523–530.
Published: 23 November 2005
... amino acid transport endothelium exercise training nitric oxide The systemic vasoconstriction observed in CHF (congestive heart failure) represents the combined effect of activation of neurohormonal systems, such as the sympathetic nervous system [ 1 ] and renin–angiotensin system [ 2...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (3): 217–226.
Published: 24 August 2005
..., cell growth, apoptosis and hypertrophy. Furthermore, NADPH oxidase-derived superoxide contributes to the impairment of endothelium-dependent vasodilatation by inactivating nitric oxide; the resultant endothelial dysfunction is implicated in the pathophysiology of diseases such as atherosclerosis...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (2): 171–176.
Published: 25 July 2005
... coronary heart disease CRP (C-reactive protein) cytokine endothelium inflammation There is substantial interest in the concept of inflammatory-driven atherogenesis in the general cardiovascular arena and, more specifically, in the autoimmune field, perhaps best exemplified by work in RA...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (1): 45–54.
Published: 23 June 2005
...-menopausal controls (277±124 pu; P <0.05), but had no effect in pre-menopausal controls (225±92 pu). These results suggest that vasoconstrictor COX products limit ACh-evoked endothelium-dependent cutaneous dilatation in the digits in pre- and post-menopausal women with PR and in post-menopausal...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (1): 27–37.
Published: 23 June 2005
... 8 3 2005 The Biochemical Society 2005 The endothelium has been shown to play a major regulatory role in the vascular response to injury. Most mechanical or haemodynamic methods of injury damage or remove vascular endothelium as part of the injury process. In fact, the loss...
Articles
Katarzyna HRYNIEWICZ, Clarito DIMAYUGA, Alhakam HUDAIHED, Ana Silvia ANDRONE, Haoyi ZHENG, Krzysztof JANKOWSKI, Stuart D. KATZ
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (4): 331–338.
Published: 22 March 2005
... ACE and PDE5 inhibition on endothelial function are warranted. Correspondence: Dr Stuart D. Katz (email [email protected] ). 2 9 2004 23 11 2004 2 12 2004 2 12 2004 The Biochemical Society 2005 angiotensin-converting enzyme (ACE) heart failure endothelium...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (4): 357–363.
Published: 22 March 2005
... of reperfusion. Using a cross-over protocol, the subjects were randomized to oral administration of 500 mg of bosentan or placebo 2 h before ischaemia. Endothelium-dependent and -independent vasodilatation were determined by intra-brachial infusion of acetylcholine (1–10 μg/min) and nitroprusside (0.3–3 μg/min...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (2): 101–112.
Published: 21 January 2005
... Society 2005 antineutrophil cytoplasm antibody (ANCA) endothelium neutrophil small vessel vasculitis SVV (small vessel vasculitis) is an inflammatory disorder affecting arterioles, capillaries and post-capillary venules and is characterized by focal necrosis of the blood vessels...
Articles
Marta ESCRIBANO-BURGOS, Antonio LÓPEZ-FARRÉ, María del MAR GONZÁLEZ, Carlos MACAYA, Antonio GARCÍA-MÉNDEZ, Petra J. MATEOS-CÁCERES, Sergio ALONSO-ORGAZ, Carolina CARRASCO, Luis A. RICO, Juan Carlos PORRES CUBERO
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (1): 85–91.
Published: 15 December 2004
... such as TNF-α. Correspondence: Dr Juan Carlos Porres Cubero (email [email protected] ). 23 7 2004 22 9 2004 24 9 2004 24 9 2004 The Biochemical Society 2005 CD32 receptor C-reactive protein (CRP) endothelium endothelial nitric oxide synthase (eNOS) inflammation...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 107 (6): 519–532.
Published: 24 November 2004
...Stuart A. RITCHIE; Marie-Ann EWART; Colin G. PERRY; John M. C. CONNELL; Ian P. SALT Vascular integrity in the healthy endothelium is maintained through the release of a variety of paracrine factors such as NO (nitric oxide). Endothelial dysfunction, characterized by reduced NO bioavailability...
Articles
Roger CORDER, Richard C. WARBURTON, Noorafza Q. KHAN, Ruth E. BROWN, Elizabeth G. WOOD, Delphine M. LEES
Journal:
Clinical Science
Clin Sci (Lond) (2004) 107 (5): 513–517.
Published: 26 October 2004
...Roger CORDER; Richard C. WARBURTON; Noorafza Q. KHAN; Ruth E. BROWN; Elizabeth G. WOOD; Delphine M. LEES Reduced endothelium-dependent vasodilator responses with increased synthesis of ET-1 (endothelin-1) are characteristics of endothelial dysfunction in heart failure and are predictive...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 107 (3): 323–330.
Published: 24 August 2004
...). By contrast, aspirin had no effect on increases in RCF evoked by iontophoretic application of the NO (nitric oxide) donor and endothelium-independent dilator sodium nitroprusside (mean increases in RCF were 73.8±9.8 PU before and 79.1±12.2 PU after aspirin). The ACh-evoked increases in RCF were also...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 107 (2): 191–196.
Published: 27 July 2004
... for 2.5 min. FMD of the brachial artery, resulting from ischaemia-induced reactive hyperaemia following release of this cuff, provided a measure of endothelium-dependent-mediated vasodilation [ 10 , 11 ]. FMD measures were repeated at 60 and 120 min after the initial baseline measure...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 106 (5): 541–546.
Published: 01 May 2004
...Chia-Hung YEN; Ying-Tung LAU 17β-Oestradiol (E 2 ; oestrogen) is known to increase endothelium-dependent vasodilatation and NO (nitric oxide) production. It is also known to decrease the response of VSMCs (vascular smooth muscle cells) to vasoconstrictors in vitro . E 2 induces a decrease in age...
Articles
Folkert W. ASSELBERGS, Stefan H.J. MONNINK, Nic J.G.M. VEEGER, Ad J. VAN BOVEN, Paul L. VAN HAELST, Gillian A.J. JESSURUN, Wiek H. VAN GILST, René A. TIO
Journal:
Clinical Science
Clin Sci (Lond) (2004) 106 (2): 115–120.
Published: 01 February 2004
... to the endothelium. Correspondence: Dr Folkert W. Asselbergs (e-mail [email protected] ). 1 Both authors contributed equally to this paper. 24 6 2003 22 8 2003 4 9 2003 4 9 2003 © 2004 The Biochemical Society 2004 acetylcholine atherosclerosis coronary...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2003) 105 (3): 251–266.
Published: 01 September 2003
... underlies many of the beneficial actions of the statins on vascular endothelium, which include increased endothelial nitric oxide synthase expression, pro-angiogenic effects, increased fibrinolytic activity, immunomodulatory and anti-inflammatory actions, including increased resistance to complement...
Articles
Maarten T. M. RAIJMAKERS, Geurt W. SCHILDERS, Eva Maria ROES, Lambertus J. H. VAN TITS, Heidy L. M. HAK-LEMMERS, Eric A. P. STEEGERS, Wilbert H. M. PETERS
Journal:
Clinical Science
Clin Sci (Lond) (2003) 105 (2): 173–180.
Published: 01 August 2003
.... Correspondence: Dr W. H. M. Peters (e-mail [email protected] ). 31 1 2003 17 4 2003 23 4 2003 23 4 2003 © 2003 The Biochemical Society 2003 antioxidant endothelium free radical homocysteine redox balance Clinical Science (2003) 105, 173 180 (Printed in Great Britain...
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