... evolution, although it reduced basal glycaemia and insulin resistance. L. coryniformis administration to HFD-induced obese mice induced marked changes in microbiota composition and reduced the metabolic endotoxaemia as it decreased the LPS (lipopolysaccharide) plasma level, which was associated...

... by a range of inflammatory mediators, both in vitro and in vivo . We propose that metabolic endotoxaemia, caused by impaired gastric mucosa and low-grade chronic inflammation, may contribute to the onset and progression of OA in obese patients. This may account for the association between obesity and OA...

... tool. Different breathing patterns may affect HRV, but results obtained under static conditions are conflicting. HRV indices decrease considerably during systemic inflammation evoked by experimental endotoxaemia, enabling the determination of the effects of different breathing patterns on HRV...

... and urine sodium respectively) and PCr and UCr (serum and urine creatinine respectively) using the equation: adenovirus β 2 -adrenoceptor endotoxaemia gene delivery kidney TNF (tumour necrosis factor) In clinical trials with adenoviral vectors, route-dependent efficacy of gene...

...-constant infusions of p -aminohippurate and 3 H-labelled isotopes were used to measure glucose, amino acid and protein metabolism across the portal-drained viscera, liver and hindquarters (to represent muscle) at 0 and 24h of endotoxaemia. Whole-body protein and glucose flux were increased during...

...Tory A. Meyer; Jing Jing Wang; Gregory M. Tiao; Cora K. Ogle; Josef E. Fischer; Per-Olof Hasselgren 1. In previous studies, experimental endotoxaemia was found to stimulate cytokine production in the central nervous system. The effect of sepsis on brain cytokines is not fully known. We compared...

..., induced by lipopolysaccharide, was markedly inhibited in the same tissues. 4. The down-regulation of COX-1 and upregulation of COX-2 may contribute to the multi-organ failure seen in sepsis. cyclo-oxygenase endotoxaemia gene regulation nitric oxide synthase prostaglandin G/H synthase Clinical...

... protein synthesis in the same cells, probably by energy provision. 26 4 1995 17 5 1995 © 1995 The Biochemical Society and the Medical Research Society 1995 endotoxaemia enterocytes glutamine protein synthesis sepsis small intestine Clinical Science (1995) 89, 311-319...