... controls, 76 patients), but antipyrine was much less sensitive as a marker of enzyme induction. This suggests that enzyme induction in pancreatic disease preferentially involves the polycyclic aromatic hydrocarbon-inducible subfamily of cytochrome P -450. 4. The lack of correlation between pancreatic...

... Society and the Medical Research Society 1982 bilirubin conjugation bilirubin secretion enzyme induction glucuronosyltransferase heterozygous Gunn rats Clinical Science (1982) 62,521-528 521 Maximal biliary secretion of bilirubin in the anaesthetized rat: dependence on UDP...

...C. H. Bolton; LYN Jackson; C. J. C. Roberts; M. Hartog 1. Serum and lipoprotein cholesterol and triglycerides were measured before, during and after the administration of glutethimide (500 mg daily) for 21 days to six healthy volunteer subjects. 2. Evidence of enzyme induction was provided...

... Research Society 1977 cholesterol ethanol microsomes liver enzyme induction phenobarbitone triglycerides Clinical Science and Molecular Medicine (1977) 52, 219-222. SHORT COMMUNICATION Accentuation of ethanol-induced fatty liver by phenobarbitone A. R. MARSH,* H. S. FRASER, A. BRECKENRIDGE...

... epileptic subjects, there was a significant correlation between d-glucaric acid excretion and plasma γ-glutamyl transpeptidase activity. 24 4 1974 © 1974 The Biochemical Society and the Medical Research Society 1974 d-glucaric acid plasma γ-glutamyl transpeptidase enzyme induction...

... but there was no significant change in the values for the apparent V or apparent K, for the glucuronidation of bilirubin with various concentrations of both UDPGA and bilirubin. Key words : antipyrine, phenobarbitone, bilirubin, enzyme induction, glucuronosyl- transferase. Gilbert's syndrome represents the most common form...

... with phenobarbitone depleted the tissue radioactivity of rats given radioactive vitamin D 3 . 1 10 1973 © 1974 The Biochemical Society and the Medical Research Society 1974 cholecalciferol vitamin D phenobarbital enzyme induction bile glucuronides Clinical Science and Molecular Medicine...