... to cardiac rupture. Moreover, IL-33-treated MI mice displayed a significant myocardial eosinophil infiltration at 7 days post-MI when compared with vehicle-treated MI mice. The present study reveals that although IL-33 administration is associated with a reparative phenotype following MI, it worsens cardiac...

...Xia Li; Zhiyuan Wang; Lihong Chang; Xiaohong Chen; Luoying Yang; Xiaoping Lai; Shuaixiang Li; Jiancong Huang; Zizhen Huang; Xifu Wu; Joseph A Bellanti; Song Guo Zheng; Gehua Zhang Eosinophilic chronic rhinosinusitis with nasal polyps (ECRS) is a condition linked with type 2 inflammation, poor...

... inflammation is attenuated in absence of either IL-17A or IL-17F with reduced airway hyperreactivity, eosinophilic inflammation, goblet cell hyperplasia, cytokine and chemokine production as found in absence of IL-17RA. Furthermore, specific antibody neutralization of either IL-17A or IL-17F given during...

...A.J. WARDLAW; C.E. BRIGHTLING; R. GREEN; G. WOLTMANN; P. BRADDING; I.D. PAVORD Asthma is a condition characterized by variable airflow obstruction, airway hyper-responsiveness (AHR) and airway inflammation which is usually, but not invariably, eosinophilic. Current thoughts on the pathogenesis...