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1-12 of 12
Keywords: epidermal growth factor
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (1999) 97 (3): 385–390.
Published: 24 August 1999
... of repair processes following wounding of the colonic mucosa. 12 10 1998 23 12 1998 19 1 1999 The Biochemical Society and the Medical Research Society © 1999 1999 interleukin-8 colon cell migration short-chain fatty acids protein kinase C epidermal growth factor tumour...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (4): 503–507.
Published: 01 October 1996
...R. A. Goodlad; R. Boulton; R. J. Playford 1. Epidermal growth factor is secreted into the gut lumen as a 53 amino acid peptide in vivo. Several preliminary studies have examined the clinical benefit of recombinant epidermal growth factor in intestinal disease, but there is inconsistency in the form...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 90 (5): 427–431.
Published: 01 May 1996
...Martin H. Ulshen; Ralph H. Raasch 1. Fasting causes atrophy of small bowel mucosa which rapidly resolves with luminal feeding. This effect of enteral nutrient-5-be mediated by stimulation of growth factor secretion. We therefore evaluated whether luminal administration of epidermal growth factor...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (4): 401–403.
Published: 01 April 1995
...Rebecca Chinery; Raymond J. Playford 1. The availability of recombinant epidermal growth factor provides a potentially exciting development for the treatment of gastrointestinal ulceration. However, because of its potent mitogenic activity, there is a need for strategies which reduce the dose...
Articles
KO Yon, Willy Nettekoven, Roger Christian, Andreas J. Wieczorek, Rainer Düsing, Hans Vetter, Agapios Sachinidis
Journal:
Clinical Science
Clin Sci (Lond) (1993) 84 (4): 435–440.
Published: 01 April 1993
... increase in total cell protein, whereas no changes in DNA synthesis were observed. 3. Acutely, insulin enhanced the mitogenic effect of epidermal growth factor and angiotensin II. Long-term treatment with 10 and 100 ng/ml insulin over 14 weeks was associated with a time-dependent reduction...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (5): 581–587.
Published: 01 May 1992
...J. Jankowski; H. J. Al-Rawi; D. A. Johnston; D. Hopwood; M. I. Filipe; G. Coghill; K. G. Wormsley 1. Epidermal growth factor and the related peptide transforming growth factor α have been implicated in the stimulation of gastric mucosal proliferation. We assessed the immunohistochemical...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (5): 573–580.
Published: 01 May 1992
...M. Salleh; M. Ardawi 1. The effects of parenteral nutrition with or without glutamine supplementation and epidermal growth factor treatment (0.15 μg/g body weight) was studied in the small bowel of septic rats after 4 days. 2. Septic rats infused with glutamine-supplemented parenteral nutrition...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1991) 81 (5): 663–668.
Published: 01 November 1991
...J. Jankowski; R. McMenemin; D. Hopwood; J. Penston; K. G. Wormsley 1. In order to assess potential abnormalities in the control of mucosal proliferation, 30 patients with Barrett's oesophagus were studied in order to evaluate the presence and distribution of epidermal growth factor, transforming...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 79 (5): 425–427.
Published: 01 November 1990
...S. M. Kelly; J. O. Hunter 1. The effects of epidermal growth factor on the synthesis and secretion by human gastric mucosa of radiolabelled mucus glycoprotein have been studied in organ culture. 2. Addition of epidermal growth factor at a concentration of 5 or 10 ng/ml increased the synthesis...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 78 (5): 445–450.
Published: 01 May 1990
...Jill Norman; Yong-Kwei Tsau; Angelito Bacay; Leon G. Fine 1. Severe, ischaemic, acute tubular necrosis was induced in rats by bilateral occlusion of the renal arteries. The experimental group received exogenous epidermal growth factor infused directly into the renal arterial circulation. Serum...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 76 (6): 595–598.
Published: 01 June 1989
...R. A. Goodlad; H. Gregory; N. A. Wright 1. Intestinal epithelial cell proliferation was measured in rats maintained on total parenteral nutriton (TPN), in TPN rats given 300 μg of recombinant human epidermal growth factor (urogastrone-epidermal growth factor, URO-EGF) day −1 kg −1 , and in further...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (2): 121–126.
Published: 01 August 1988
...R. A. Goodlad; A. P. Savage; W. Lenton; M. A. Ghatei; H. Gregory; S. R. Bloom; N. A. Wright 1. The objective of this study was to see whether another proliferative stimulus could modify the marked proliferative effect of human epidermal growth factor (urogastrone-epidermal growth factor, URO-EGF...