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Keywords: epithelial–mesenchymal transition
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (12): 1309–1320.
Published: 19 June 2019
... 03 06 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 angiogenesis epithelial-mesenchymal transition inflammation myofibroblasts Nintedanib renal fibrosis The INPULSIS trials, two double-blind, randomized, placebo...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (19): 2439–2450.
Published: 22 September 2017
... mesenchymal biomarker expression, then promoted cell migration, invasion, and proliferation. Interestingly, we found that TrpC5 mediated hypoxia-inducible factor 1α (HIF-1α) expression, activating Twist to promote the epithelial–mesenchymal transition (EMT). Notably, patients with high expression of TrpC5...
Includes: Supplementary data
Articles
Isadora L. Flores, Rebeca Kawahara, Márcia C.C. Miguel, Daniela C. Granato, Romênia R. Domingues, Carolina C.S. Macedo, Carolina M. Carnielli, Sami Yokoo, Priscila C. Rodrigues, Bárbara V.B. Monteiro, Carine E. Oliveira, Cristiane R. Salmon, Francisco H. Nociti, Jr, Márcio A. Lopes, Alan Santos-Silva, Flavia V. Winck, Ricardo D. Coletta, Adriana F. Paes Leme
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (10): 785–799.
Published: 01 April 2016
... the activation of cyclin D1 and vimentin proteins. EEF1D knockdown in OSCC reduced cell proliferation and induced EMT (epithelial–mesenchymal transition) phenotypes, including cell invasion. Taken together, these results define EEF1D as a critical inducer of OSCC proliferation and EMT. EEF1D modulates...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (10): 459–472.
Published: 26 January 2012
..., augmented the epithelial–mesenchymal transition and more resistance to treatment. Activated IL-6 (interleukin-6) signalling could be the mechanism underlying the effects of TGF-β1 on oral cancer. Regarding clinical data, the incidence of TGF-β1 immunoreactivity in oral cancer specimens was significantly...