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Keywords: erectile dysfunction
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Articles
Clin Sci (Lond) (2020) 134 (22): 2929–2941.
Published: 16 November 2020
... Ang-(1-7). ACE2 Angiotensin-(1-7) erectile dysfunction Mas receptor ovulation reproduction The renin–angiotensin system (RAS) is an endocrine and paracrine regulatory system composed by peptides that selectively bind cell surface receptors and activate downstream cytoplasmic signals...
Articles
Clin Sci (Lond) (2006) 110 (2): 153–165.
Published: 17 January 2006
... dissociation inhibitors and GTPase-activating proteins. We also summarize the current knowledge about the physiological roles of RhoA/Rho-kinase in both male and female erectile tissues and its aberrations contributing to erectile dysfunction in several disease states. Understanding the RhoA/Rho-kinase...
Articles
Clin Sci (Lond) (2000) 99 (4): 255–260.
Published: 06 September 2000
...Simon F. CAMPBELL The research programme that started in 1985 led to the approval of Sildenafil (Viagra ® ), in 1998, as the first oral treatment for male erectile dysfunction. The initial project objective was the design and synthesis of novel inhibitors of phosphodiesterase that would increase...