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Keywords: erythrocyte
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Clin Sci (Lond) (1999) 97 (3): 283–290.
Published: 15 July 1999
... suggested that it can directly alter transport processes at the plasma membrane. To examine this possibility in a physiological context, we determined Na + /K + -ATPase activity in erythrocytes from two groups of subjects receiving CsA treatment: group I consisted of kidney transplant patients, and group II...
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Clin Sci (Lond) (1999) 96 (2): 171–178.
Published: 01 February 1999
...Bridget E. BAX; Murray D. BAIN; Peter J. TALBOT; E. John PARKER-WILLIAMS; Ronald A. CHALMERS Erythrocytes offer the exciting opportunity of being used as carriers of therapeutic agents. Encapsulation within erythrocytes will give the therapeutic agent a clearance equivalent to the normal life...
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Clin Sci (Lond) (1993) 85 (5): 585–591.
Published: 01 November 1993
...Robert I Norman; Navtej Achall 1. The relationships between systolic blood pressure and altered erythrocyte Ca 2+ -Mg 2+ -ATPase activity and membrane microviscosity were assessed in membranes prepared from 20-week-old female Wistar-Kyoto normotensive and spontaneously hypertensive rats obtained...
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Clin Sci (Lond) (1992) 82 (4): 341–352.
Published: 01 April 1992
...P. A. Rutherford; T. H. Thomas; R. Wilkinson Clinical Science (1992) 82, 341-352 (Printed in Great Britain) Editorial Review 34 I Erythrocyte sodium-lithium countertransport: clinically useful, pathophysiologically instructive or just phenomenology ? P. A. RUTHERFORD, T. H. THOMAS and R. WlLKlNSON...
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Clin Sci (Lond) (1992) 82 (3): 291–299.
Published: 01 March 1992
...Peter A. Rutherford; Trevor H. Thomas; Susan J. Carr; Roy Taylor; Robert Wllklnson 1. Increased erythrocyte sodium-lithium countertransport activity has been reported to be associated with nephropathy in type 1 diabetes and linked to a family history of essential hypertension. 2. This study aimed...
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Clin Sci (Lond) (1992) 82 (3): 301–307.
Published: 01 March 1992
...Peter A. Rutherford; Trevor H. Thomas; Susan J. Carr; Roy Taylor; Robert Wilkinson 1. It has been proposed that raised erythrocyte sodium-lithium countertransport activity in type 1 diabetic patients is associated with an increased risk of developing diabetic nephropathy. Diabetic patients...
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Clin Sci (Lond) (1992) 82 (1): 99–104.
Published: 01 January 1992
...J. F. St. J. Dwight; A. C. Mendes Ribeiro; B. M. Hendry 1. Sodium pump function has been assessed by measurement of ouabain-sensitive 86 Rb uptake in human erythrocytes after incorporation of palmitic, stearic, oleic and linoleic acids into the erythrocyte membrane. 14 C-labelled fatty acids were...
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Clin Sci (Lond) (1992) 82 (1): 9–11.
Published: 01 January 1992
...Junichi Utoh; Hiroaki Harasaki 1. Erythrocytes are known to haemolyse in vitro at 48–50°C. We hypothesized that erythrocytes might be damaged at much lower temperatures if they are incubated for prolonged periods. Erythrocytes from healthy human donors ( n = 7) were incubated at 37, 40, 42, 44, 46...
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Clin Sci (Lond) (1991) 81 (1): 107–112.
Published: 01 July 1991
...K. Fujito; M. Yokomatsu; N. Ishiguro; H. Numahata; Y. Tomino; H. Koide 1. The purpose of this study was to determine the effect of dietary Ca 2+ intake on blood pressure and erythrocyte Na + transport in spontaneously hypertensive rats. 2. Spontaneously hypertensive rats and Wistar-Kyoto rats were...
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Clin Sci (Lond) (1991) 80 (2): 137–141.
Published: 01 February 1991
...F. C. Fervenza; D. Meredith; J. C. Ellory; B. M. Hendry 1. Erythrocyte choline transport has been studied in nine patients on maintenance haemodialysis for chronic renal failure, six patients on continuous ambulatory peritoneal dialysis, 31 patients with renal transplants and in nine normal control...
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Clin Sci (Lond) (1990) 79 (6): 631–638.
Published: 01 December 1990
...S. MacPhail; T. H. Thomas; R. Wilkinson; J. M. Davison; W. Dunlop 1. Normotensive primigravid pregnant women were studied longitudinally during pregnancy and 20 weeks after delivery. 2. Erythrocyte sodium content, ouabain-sensitive sodium flux and sodium pump rate constant were measured in whole...
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Clin Sci (Lond) (1990) 79 (4): 387–391.
Published: 01 October 1990
...W. H. Reinhart; F. Rohner 1. Amiodarone is a potent anti-arrhythmic drug with lipophilic properties. The intercalation of such a drug into the membrane of erythrocytes may alter their shape and have an impact on the flow properties of blood. We therefore studied the influence of amiodarone...
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Clin Sci (Lond) (1989) 77 (2): 213–216.
Published: 01 August 1989
...G. Dagher; M. C. Vantyghem; B. Doise; G. Lallau; A. Racadot; J. Lefebvre 1. Erythrocyte cation transport pathways have been investigated in a family with pseudohyperkalaemia. 2. Ouabain- and bumetanide-resistant Na + and K + effluxes in three pseudohyperkalaemic patients were not different from...
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Clin Sci (Lond) (1989) 76 (4): 419–422.
Published: 01 April 1989
...F. C. Fervenza; C. M. Harvey; B. M. Hendry; J. C. Ellory 1. The initial rate of l -lysine influx into erythrocytes from 13 patients with chronic renal failure has been measured using 14 C-labelled lysine. Ten patients were on maintenance haemodialysis and three had never been dialysed. The results...
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Clin Sci (Lond) (1986) 71 (6): 639–646.
Published: 01 December 1986
... was slightly lower. 3. Renal failure caused resetting of erythropoietic control to a lower level of packed cell volume (PCV). After 7 days renal failure some rats had a low PCV, whereas others still had a normal PCV apparently due to slower erythrocyte destruction of pre-renal failure cells. 4. After 7 days...
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Clin Sci (Lond) (1986) 70 (3): 263–269.
Published: 01 March 1986
...Eileen D. M. Gallery; Catherine Bean; Roslyn Grigg; Douglas M. Saunders 1. Electrolyte transport characteristics were examined in erythrocytes from 13 normal men and from two groups of women: (i) taking combined oral contraceptive preparations (O/C, n = 10), and (ii) ovulatory women (non-O/C, n...
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Clin Sci (Lond) (1984) 66 (3): 365–368.
Published: 01 March 1984
...Kevin Morgan; M. Afzal Mir 1. Previous studies have shown that myeloid leukaemic blast cells contain a heat stable factor which inhibits bidirectional sodium transport in normal erythrocytes. This study was undertaken to establish whether leukaemic promyelocytes in culture secrete this factor. 2...
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Clin Sci (Lond) (1983) 65 (5): 515–519.
Published: 01 November 1983
...I. B. Kovacs; S. O. Sowemimo-Coker; J. D. T. Kirby; P. Turner 1. Filterability (deformability) of erythrocytes of patients with Raynaud's phenomenon together with progressive systemic sclerosis (PSS) was decreased compared with the filtration of erythrocytes from normal subjects. 2. PSS...
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Clin Sci (Lond) (1983) 64 (4): 441–447.
Published: 01 April 1983
...E. Jill Rubython; M. Cumberbatch; D. B. Morgan 1. The sodium content, the rate and rate constant of ouabain-sensitive sodium efflux and the number of sodium pumps (indicated by the ouabain-binding capacity) were measured in erythrocytes from patients with hyperthyroidism and compared with values...
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Clin Sci (Lond) (1982) 63 (s8): 57s–59s.
Published: 01 October 1982
...D. Cusi. C. Barlassina; M. Ferrandi; R. Brevi; A. Vazzola; G. Bianchi 1. Erythrocyte Na + -K + cotransport and Na + -Li + countertransport were measured at the same time in 56 essential hypertensive patients, 24 of their normotensive offspring and 36 matched normotensive controls. 2. The mean value...
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Clin Sci (Lond) (1982) 63 (1): 43–45.
Published: 01 July 1982
...S. N. Orlov; P. V. Gulak; I. S. Litvinov; YU. V. Postnov 1. The membrane structure of erythrocytes of rats with different forms of arterial hypertension was studied by means of two hydrophobic fluorescent probes (diphenylhexatriene and pyrene). 2. Microviscosity of hydrophobic areas of erythrocyte...
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Clin Sci (Lond) (1982) 62 (5): 479–488.
Published: 01 May 1982
...G. P. Summerfield; A. J. Bellingham; L. Manlove; A. M. Forbes; H. J. Goldsmith 1. Erythrocyte metabolism was investigated and glycolytic intermediates were measured in nine patients with chronic renal failure who were subsequently treated with haemodialysis. The same' investigations were performed...
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Clin Sci (Lond) (1981) 61 (s7): 29s–32s.
Published: 01 December 1981
...M. Trevisan; R. Cooper; D. Ostrow; W. Miller; S. Sparks; Y. Leonas; A. Allen; M. Steinhauer; J. Stamler 1. There was a significant positive relationship between sodium-stimulated lithium efflux and systolic blood pressure ( r = 0.512) in erythrocytes of black school children. Weight was also...
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Clin Sci (Lond) (1981) 61 (s7): 37s–39s.
Published: 01 December 1981
...J. B. Myers; W. R. Fitzgibbon; T. O. Morgan 1. Present results confirm our previous work which showed that a sodium intake over 3 mmol day −1 kg −1 decreased the total erythrocyte efflux rate constant in untreated males with essential hypertension. 2. The infusion of saline (2.25 mmol of Na + /kg...
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Clin Sci (Lond) (1981) 60 (5): 555–564.
Published: 01 May 1981
...M. Cumberbatch; D. B. Morgan 1. We have examined the inter-relationships between erythrocyte sodium content and sodium transport in a group of healthy subjects and in groups of patients with disorders known to change the sodium content of erythrocytes. 2. In the healthy subjects the sodium content...
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Clin Sci (Lond) (1980) 59 (3): 163–168.
Published: 01 September 1980
...M. Brada; L. A. Robinson; A. J. Bellingham 1. As it has been suggested that the beneficial effect of methylprednisolone in shock is due to its effect on erythrocyte oxygen affinity, we studied its effect on incubated erythrocytes and on haemoglobin solution. 2. Incubation of fresh whole blood...
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Clin Sci (Lond) (1980) 58 (3): 255–257.
Published: 01 March 1980
...R. Lindsay; D. M. Hart; C. Forrest 1. Serum, urinary and erythrocyte magnesium concentrations were measured in groups of premenopausal, postmenopausal and oophorectomized women. 2. Serum and urinary magnesium were both significantly higher in postmenopausal and oophorectomized women than...
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Clin Sci Mol Med (1975) 49 (5): 375–384.
Published: 01 November 1975
...N. Worathumrong; A. J. Grimes 1. Some effects of sodium salicylate upon anaerobic glycolysis have been studied in normal human erythrocytes incubated for up to 6 h at 37°C in autologous sera. 2. Both glucose consumption and lactate production were stimulated by concentrations of salicylate up to 60...
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Clin Sci Mol Med (1975) 48 (3): 213–218.
Published: 01 March 1975
...M. Afzal Mir; H. Bobinski 1. Sodium transport studies were performed in erythrocytes from normal subjects and from patients with acute myeloid leukaemia. Sodium influx and efflux rates were increased in erythrocytes from leukaemic patients. 2. The ouabain-sensitive component of sodium efflux...
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Clin Sci Mol Med (1975) 48 (3): 239–242.
Published: 01 March 1975
...C. H. Cole; R. Maletz 1. Intracellular electrolytes, and erythrocyte membrane adenosine triphosphatase (ATPase) activity, was studied in twenty patients after renal transplantation. 2. The mean ouabain-sensitive ATPase activity in the erythrocyte membranes of the transplant patients was 122 nmol...