1-50 of 51
Keyword: erythrocyte
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Clin Sci (Lond) (2004) 107 (1): 63–68.
Published: 23 June 2004
... lymphocyte IMPDH (inosine monophosphate dehydrogenase), thereby drastically decreasing GTP concentrations essential to lymphocyte proliferation in vitro and in vivo . Erythrocyte GTP concentrations are commonly elevated in severe renal disease, but normalize following successful engraftment. Consequently...
Articles
Clin Sci (Lond) (1999) 97 (3): 283–290.
Published: 15 July 1999
... suggested that it can directly alter transport processes at the plasma membrane. To examine this possibility in a physiological context, we determined Na + /K + -ATPase activity in erythrocytes from two groups of subjects receiving CsA treatment: group I consisted of kidney transplant patients, and group II...
Articles
Clin Sci (Lond) (1999) 96 (2): 171–178.
Published: 01 February 1999
...Bridget E. BAX; Murray D. BAIN; Peter J. TALBOT; E. John PARKER-WILLIAMS; Ronald A. CHALMERS Erythrocytes offer the exciting opportunity of being used as carriers of therapeutic agents. Encapsulation within erythrocytes will give the therapeutic agent a clearance equivalent to the normal life of...
Articles
Clin Sci (Lond) (1998) 95 (6): 649–657.
Published: 01 December 1998
...T. Tepper; W. J. Sluiter; R. M. Huisman; D. de Zeeuw 1. A meta-analysis of 17 years of literature on erythrocyte Na + /Li + countertransport (NLCT) and Na + /K + co-transport (COT) measurements in relation to essential hypertension is presented. The analysis aimed to answer two questions: (i) Which...
Includes: Supplementary data
Articles
Clin Sci (Lond) (1994) 86 (3): 239–243.
Published: 01 March 1994
...Bruno Baggio; Giovanni Gambaro; Francesco Marchini; Massimo Vincenti; Giulio Ceolotto; Achille C. Pessina; Andrea Semplicini 1. Anomalous transmembrane anion transport has been observed in erythrocytes of patients with idiopathic calcium nephrolithiasis. 2. To verify whether cation transport is...
Articles
Clin Sci (Lond) (1993) 85 (5): 585–591.
Published: 01 November 1993
...Robert I Norman; Navtej Achall 1. The relationships between systolic blood pressure and altered erythrocyte Ca 2+ -Mg 2+ -ATPase activity and membrane microviscosity were assessed in membranes prepared from 20-week-old female Wistar-Kyoto normotensive and spontaneously hypertensive rats obtained...
Articles
Clin Sci (Lond) (1993) 85 (1): 41–44.
Published: 01 July 1993
...Giovanni Gambaro; Massimo Vincenti; Francesco Marchini; Angela D'Angelo; Bruno Baggio 1. The demonstration of an inheritable anomaly of erythrocyte oxalate transport in ‘primary’ calcium nephrolithiasis suggested that this disease might be a generalized metabolic disorder characterized by a defect...
Articles
Clin Sci (Lond) (1992) 83 (2): 213–219.
Published: 01 August 1992
...J. F. R. Barrett; P. G. Whittaker; J. G. Williams; T. Lind 1. Iron absorption has been quantitatively measured as the incorporation of physiological doses of stable iron isotopes into erythrocytes. Five milligrams of 57 Fe (orally) and 250 μg of 58 Fe (intravenously) were given to five healthy...
Articles
Clin Sci (Lond) (1992) 82 (4): 341–352.
Published: 01 April 1992
...P. A. Rutherford; T. H. Thomas; R. Wilkinson © 1992 The Biochemical Society and the Medical Research Society 1992 diabetes mellitus erythrocyte hyperlipidaemia hypertension lithium pregnancy sodium Clinical Science (1992) 82, 341-352 (Printed in Great Britain) Editorial Review 34...
Articles
Clin Sci (Lond) (1992) 82 (3): 291–299.
Published: 01 March 1992
...Peter A. Rutherford; Trevor H. Thomas; Susan J. Carr; Roy Taylor; Robert Wllklnson 1. Increased erythrocyte sodium-lithium countertransport activity has been reported to be associated with nephropathy in type 1 diabetes and linked to a family history of essential hypertension. 2. This study aimed...
Articles
Clin Sci (Lond) (1992) 82 (3): 301–307.
Published: 01 March 1992
...Peter A. Rutherford; Trevor H. Thomas; Susan J. Carr; Roy Taylor; Robert Wilkinson 1. It has been proposed that raised erythrocyte sodium-lithium countertransport activity in type 1 diabetic patients is associated with an increased risk of developing diabetic nephropathy. Diabetic patients with...
Articles
Clin Sci (Lond) (1992) 82 (1): 99–104.
Published: 01 January 1992
...J. F. St. J. Dwight; A. C. Mendes Ribeiro; B. M. Hendry 1. Sodium pump function has been assessed by measurement of ouabain-sensitive 86 Rb uptake in human erythrocytes after incorporation of palmitic, stearic, oleic and linoleic acids into the erythrocyte membrane. 14 C-labelled fatty acids were...
Articles
Clin Sci (Lond) (1992) 82 (1): 9–11.
Published: 01 January 1992
...Junichi Utoh; Hiroaki Harasaki 1. Erythrocytes are known to haemolyse in vitro at 48–50°C. We hypothesized that erythrocytes might be damaged at much lower temperatures if they are incubated for prolonged periods. Erythrocytes from healthy human donors ( n = 7) were incubated at 37, 40, 42, 44, 46...
Articles
Clin Sci (Lond) (1991) 81 (1): 107–112.
Published: 01 July 1991
...K. Fujito; M. Yokomatsu; N. Ishiguro; H. Numahata; Y. Tomino; H. Koide 1. The purpose of this study was to determine the effect of dietary Ca 2+ intake on blood pressure and erythrocyte Na + transport in spontaneously hypertensive rats. 2. Spontaneously hypertensive rats and Wistar-Kyoto rats were...
Articles
Clin Sci (Lond) (1991) 80 (4): 313–318.
Published: 01 April 1991
...Brice Lerique; Marguerite Gastaldi; Jean Boyer 1. Triacylglycerol in erythrocytes from normal human subjects was estimated to average 2.7 ± 0.7 nmol/10 10 cells, equivalent to 0.07% of total lipids or 0.3% of neutral lipids. 2. The specific activity of triacylglycerol labelling attained by...
Articles
Clin Sci (Lond) (1991) 80 (2): 137–141.
Published: 01 February 1991
...F. C. Fervenza; D. Meredith; J. C. Ellory; B. M. Hendry 1. Erythrocyte choline transport has been studied in nine patients on maintenance haemodialysis for chronic renal failure, six patients on continuous ambulatory peritoneal dialysis, 31 patients with renal transplants and in nine normal control...
Articles
Clin Sci (Lond) (1990) 79 (6): 631–638.
Published: 01 December 1990
...S. MacPhail; T. H. Thomas; R. Wilkinson; J. M. Davison; W. Dunlop 1. Normotensive primigravid pregnant women were studied longitudinally during pregnancy and 20 weeks after delivery. 2. Erythrocyte sodium content, ouabain-sensitive sodium flux and sodium pump rate constant were measured in whole...
Articles
Clin Sci (Lond) (1990) 79 (6): 625–630.
Published: 01 December 1990
...T. H. Thomas; S. MacPhail; V. Mott; R. Wilkinson 1. Young and mature erythrocytes from 15 normal subjects were used to compare the sodium pump rate constant measured in whole blood with the more definitive sodium affinity constant and maximum velocity of the sodium pump measured in artificial media...
Articles
Clin Sci (Lond) (1990) 79 (4): 365–369.
Published: 01 October 1990
...P. A. Rutherford; T. H. Thomas; R. Wilkinson 1. Sodium-lithium countertransport activity in a standard assay, its sodium affinity constant and maximum velocity were measured in erythrocytes from normal subjects and from essential hypertensive patients with and without a family history of...
Articles
Clin Sci (Lond) (1990) 79 (4): 387–391.
Published: 01 October 1990
...W. H. Reinhart; F. Rohner 1. Amiodarone is a potent anti-arrhythmic drug with lipophilic properties. The intercalation of such a drug into the membrane of erythrocytes may alter their shape and have an impact on the flow properties of blood. We therefore studied the influence of amiodarone on...
Articles
Clin Sci (Lond) (1989) 77 (2): 213–216.
Published: 01 August 1989
...G. Dagher; M. C. Vantyghem; B. Doise; G. Lallau; A. Racadot; J. Lefebvre 1. Erythrocyte cation transport pathways have been investigated in a family with pseudohyperkalaemia. 2. Ouabain- and bumetanide-resistant Na + and K + effluxes in three pseudohyperkalaemic patients were not different from...
Articles
Clin Sci (Lond) (1989) 76 (4): 419–422.
Published: 01 April 1989
...F. C. Fervenza; C. M. Harvey; B. M. Hendry; J. C. Ellory 1. The initial rate of l -lysine influx into erythrocytes from 13 patients with chronic renal failure has been measured using 14 C-labelled lysine. Ten patients were on maintenance haemodialysis and three had never been dialysed. The results...
Articles
Clin Sci (Lond) (1988) 75 (2): 167–170.
Published: 01 August 1988
... erythrocytes of 19 healthy volunteers, before and after supplementation of their normal diet with 6.0–8.9 g of salt (102–137 mmol of NaCl) per day, for 5 days. 2. The subjects had a small but significant gain in weight. Mean plasma renin activity decreased from 1.57 to 0.73 pmol of angiotensin I h −1 ml −1 and...
Articles
Clin Sci (Lond) (1988) 74 (2): 145–150.
Published: 01 February 1988
...E. D. M. Gallery; J. Rowe; M. A. Brown; M. Ross 1. Active electrolyte transport was examined in erythrocytes from women in the second and third trimesters of pregnancy and post partum , and compared with that in ovulating women. 2. There was a significant reduction in intracellular sodium ([Na] i...
Articles
Clin Sci (Lond) (1988) 74 (1): 57–61.
Published: 01 January 1988
...Irma Dianzani; Roberto Boero; Cesare Guarena; Antonio Urbino; Giuliana Corda; Francesco Quarello; Franco Cerutti 1. Intracellular Na + concentration [Na + ] i and Na + extrusion catalysed by sodium, potassium-activated adenosine triphosphatase (Na + , K + -pump) were evaluated in erythrocytes from...
Articles
Clin Sci (Lond) (1987) 73 (1): 29–32.
Published: 01 July 1987
...A. Riozzi; A. M. Heagerty; J. D. Ollerenshaw; J. D. Swales 1. The metabolism of phosphoinositides was investigated in erythrocyte membranes of essential hypertensive patients, normotensive offspring of hypertensive patients and matched controls. 2. Measurement of 32 P-labelling of...
Articles
Clin Sci (Lond) (1986) 71 (6): 639–646.
Published: 01 December 1986
... slightly lower. 3. Renal failure caused resetting of erythropoietic control to a lower level of packed cell volume (PCV). After 7 days renal failure some rats had a low PCV, whereas others still had a normal PCV apparently due to slower erythrocyte destruction of pre-renal failure cells. 4. After 7 days...
Articles
Clin Sci (Lond) (1986) 70 (3): 263–269.
Published: 01 March 1986
...Eileen D. M. Gallery; Catherine Bean; Roslyn Grigg; Douglas M. Saunders 1. Electrolyte transport characteristics were examined in erythrocytes from 13 normal men and from two groups of women: (i) taking combined oral contraceptive preparations (O/C, n = 10), and (ii) ovulatory women (non-O/C, n...
Articles
Clin Sci (Lond) (1986) 70 (3): 295–299.
Published: 01 March 1986
...K. Matthewson; C. O. Record 1. Erythrocyte aldehyde dehydrogenase activity was assayed in actively drinking alcoholics, patients with alcoholic liver disease who claimed to be abstaining, patients with non-alcoholic liver disorders and normal controls. Hepatic cytosolic aldehyde dehydrogenase was...
Articles
Clin Sci (Lond) (1986) 70 (2): 127–129.
Published: 01 February 1986
...C. J. Story; A. P. Roberts; R. G. Ryall 1. Erythrocyte 2,3-diphosphoglycerate and haemoglobin A 1C concentrations were measured in 26 clinically normoxic patients with type 1 (insulin dependent) diabetes mellitus. The concentration of 2,3-diphosphoglycerate theoretically required to maintain normal...
Articles
Clin Sci (Lond) (1985) 69 (4): 429–434.
Published: 01 October 1985
...A. Challa; A. Bevington; C. M. Angier; A. J. Asbury; C. J. Preston; R. G. G. Russell 1. A technique is described for the determination of orthophosphate (P i ) in human erythrocytes. The advantages of the technique are that it uses whole blood rather than separated erythrocytes, that it avoids...
Articles
Clin Sci (Lond) (1984) 66 (3): 365–368.
Published: 01 March 1984
...Kevin Morgan; M. Afzal Mir 1. Previous studies have shown that myeloid leukaemic blast cells contain a heat stable factor which inhibits bidirectional sodium transport in normal erythrocytes. This study was undertaken to establish whether leukaemic promyelocytes in culture secrete this factor. 2...
Articles
Clin Sci (Lond) (1983) 65 (5): 515–519.
Published: 01 November 1983
...I. B. Kovacs; S. O. Sowemimo-Coker; J. D. T. Kirby; P. Turner 1. Filterability (deformability) of erythrocytes of patients with Raynaud's phenomenon together with progressive systemic sclerosis (PSS) was decreased compared with the filtration of erythrocytes from normal subjects. 2. PSS...
Articles
Clin Sci (Lond) (1983) 64 (4): 441–447.
Published: 01 April 1983
...E. Jill Rubython; M. Cumberbatch; D. B. Morgan 1. The sodium content, the rate and rate constant of ouabain-sensitive sodium efflux and the number of sodium pumps (indicated by the ouabain-binding capacity) were measured in erythrocytes from patients with hyperthyroidism and compared with values...
Articles
Clin Sci (Lond) (1982) 63 (s8): 57s–59s.
Published: 01 October 1982
...D. Cusi. C. Barlassina; M. Ferrandi; R. Brevi; A. Vazzola; G. Bianchi 1. Erythrocyte Na + -K + cotransport and Na + -Li + countertransport were measured at the same time in 56 essential hypertensive patients, 24 of their normotensive offspring and 36 matched normotensive controls. 2. The mean value...
Articles
Clin Sci (Lond) (1982) 63 (s8): 61s–64s.
Published: 01 October 1982
...P. Ferrari; D. Cusi; B. Barber; C. Barlassina; G. Vezzoli; L. Duzzi; E. Minotti; G. Bianchi 1. The aim of this study was to compare certain renal and erythrocyte functions in the Milan hypertensive strain (MHS) of rats and in normotensive control animals (MNS). 2. Under experimental conditions...
Articles
Clin Sci (Lond) (1982) 63 (s8): 121s–124s.
Published: 01 October 1982
... obese patients with transport mechanisms and NA responses in age, sex and race matched non-obese subjects. In the obese subjects we examined the effects of caloric restriction and weight reduction over a 12 week period on intracellular erythrocyte cation concentrations, Na + ,K + -dependent ATPase...
Articles
Clin Sci (Lond) (1982) 63 (1): 43–45.
Published: 01 July 1982
...S. N. Orlov; P. V. Gulak; I. S. Litvinov; YU. V. Postnov 1. The membrane structure of erythrocytes of rats with different forms of arterial hypertension was studied by means of two hydrophobic fluorescent probes (diphenylhexatriene and pyrene). 2. Microviscosity of hydrophobic areas of erythrocyte...
Articles
Clin Sci (Lond) (1982) 62 (5): 479–488.
Published: 01 May 1982
...G. P. Summerfield; A. J. Bellingham; L. Manlove; A. M. Forbes; H. J. Goldsmith 1. Erythrocyte metabolism was investigated and glycolytic intermediates were measured in nine patients with chronic renal failure who were subsequently treated with haemodialysis. The same' investigations were performed...
Articles
Clin Sci (Lond) (1981) 60 (5): 555–564.
Published: 01 May 1981
...M. Cumberbatch; D. B. Morgan 1. We have examined the inter-relationships between erythrocyte sodium content and sodium transport in a group of healthy subjects and in groups of patients with disorders known to change the sodium content of erythrocytes. 2. In the healthy subjects the sodium content...
Articles
Clin Sci (Lond) (1981) 61 (s7): 13s–15s.
Published: 01 January 1981
...M. Canali; L. Borghi; E. Sani; A. Curti; A. Montanari; A. Novarini; A. Borghetti 1. Erythrocyte lithium—sodium counter-transport was measured in 46 normotensive healthy controls without family history of hypertension, 15 subjects with essential hypertension, but without evidence of family history...
Articles
Clin Sci (Lond) (1981) 61 (s7): 29s–32s.
Published: 01 January 1981
...M. Trevisan; R. Cooper; D. Ostrow; W. Miller; S. Sparks; Y. Leonas; A. Allen; M. Steinhauer; J. Stamler 1. There was a significant positive relationship between sodium-stimulated lithium efflux and systolic blood pressure ( r = 0.512) in erythrocytes of black school children. Weight was also...
Articles
Clin Sci (Lond) (1981) 61 (s7): 37s–39s.
Published: 01 January 1981
...J. B. Myers; W. R. Fitzgibbon; T. O. Morgan 1. Present results confirm our previous work which showed that a sodium intake over 3 mmol day −1 kg −1 decreased the total erythrocyte efflux rate constant in untreated males with essential hypertension. 2. The infusion of saline (2.25 mmol of Na + /kg...
Articles
Clin Sci (Lond) (1980) 59 (3): 163–168.
Published: 01 September 1980
...M. Brada; L. A. Robinson; A. J. Bellingham 1. As it has been suggested that the beneficial effect of methylprednisolone in shock is due to its effect on erythrocyte oxygen affinity, we studied its effect on incubated erythrocytes and on haemoglobin solution. 2. Incubation of fresh whole blood...
Articles
Clin Sci (Lond) (1980) 58 (6): 477–484.
Published: 01 June 1980
...G. H. Elder; Diane M. Sheppard; R. E. De Salamanca; A. Olmos 1. Erythrocyte uroporphyrinogen decarboxylase activity has been measured in 27 patients with porphyria cutanea tarda, of whom 11 had a family history of overt porphyria cutanea tarda. 2. Eight patients from six families had erythrocyte...
Articles
Clin Sci (Lond) (1980) 58 (3): 255–257.
Published: 01 March 1980
...R. Lindsay; D. M. Hart; C. Forrest 1. Serum, urinary and erythrocyte magnesium concentrations were measured in groups of premenopausal, postmenopausal and oophorectomized women. 2. Serum and urinary magnesium were both significantly higher in postmenopausal and oophorectomized women than in the...
Articles
Clin Sci Mol Med (1978) 55 (4): 407–412.
Published: 01 October 1978
...B. M. Dean; D. Perrett; H. Anne Simmonds; A. Sahota; K. J. Van Acker 1. We have studied the metabolism of adenine and adenosine in intact erythrocytes from three children and four adults of two separate families. The children were homozygotes for a deficiency of AMP-pyrophosphate...
Articles
Clin Sci Mol Med (1975) 49 (5): 375–384.
Published: 01 November 1975
...N. Worathumrong; A. J. Grimes 1. Some effects of sodium salicylate upon anaerobic glycolysis have been studied in normal human erythrocytes incubated for up to 6 h at 37°C in autologous sera. 2. Both glucose consumption and lactate production were stimulated by concentrations of salicylate up to 60...
Articles
Clin Sci Mol Med (1975) 48 (3): 213–218.
Published: 01 March 1975
...M. Afzal Mir; H. Bobinski 1. Sodium transport studies were performed in erythrocytes from normal subjects and from patients with acute myeloid leukaemia. Sodium influx and efflux rates were increased in erythrocytes from leukaemic patients. 2. The ouabain-sensitive component of sodium efflux was...
Articles
Clin Sci Mol Med (1975) 48 (3): 239–242.
Published: 01 March 1975
...C. H. Cole; R. Maletz 1. Intracellular electrolytes, and erythrocyte membrane adenosine triphosphatase (ATPase) activity, was studied in twenty patients after renal transplantation. 2. The mean ouabain-sensitive ATPase activity in the erythrocyte membranes of the transplant patients was 122 nmol of...