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Keywords: erythrocytes
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Clin Sci (Lond) (2021) 135 (11): 1353–1367.
Published: 02 June 2021
... ]. Correspondence: Michael Bader ( [email protected] ) 19 01 2021 11 05 2021 20 05 2021 20 05 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 Blood Pressure Brain RAS erythrocytes Neurophysiology Sympathetic System...
Includes: Supplementary data
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Clin Sci (Lond) (1998) 94 (1): 43–48.
Published: 01 January 1998
...H. Hanssen; T. M. C. Brunini; M. Conway; A. P. Banning; N. B. Roberts; G. E. Mann; J. C. Ellory; A. C. Mendes Ribeiro 1. Transport of l-arginine was investigated under zero- trans conditions in human erythrocytes from healthy donors and patients with heart failure. 2. Saturable influx of l-arginine...
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Clin Sci (Lond) (1998) 94 (1): 79–85.
Published: 01 January 1998
... fluorescent probes exploring either the outer membrane leaflet [trimethylamino-diphenylhexatriene (TMA-DPH)] or the lipid membrane core [diphenylhexatriene (DPH)], in platelets and erythrocytes of genetically hypertensive rats of the Prague hereditary hypertriglyceridaemic (HTG) strain. The relationships...
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Clin Sci (Lond) (1995) 88 (4): 405–412.
Published: 01 April 1995
...Alan Bevington; Dennis Brough; Frease E. Baker; Jane Hattersley; John Walls 1. During metabolic acidosis, significant fluxes of inorganic phosphate (P i ) may occur from cellular to extracellular fluid. In this study P i was measured in erythrocytes of uraemic patients before and after...
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Clin Sci (Lond) (1994) 86 (1): 11–13.
Published: 01 January 1994
...Jaroslav Kuneš; Hassan Karama Bin Talib; Zdena DobešOvá; Antonín Vrána; Josef Zicha 1. Hypertension appears to be associated with both abnormalities in ion transport and disturbances in lipid metabolism. The aim of the present study was to search for alterations in erythrocyte ion transport...
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Clin Sci (Lond) (1993) 84 (4): 401–405.
Published: 01 April 1993
...G. D. Webb; G. G. Ashmead; S. Al-Mahdi; F. J. Auletta; M. K. McLaughlin 1. We have studied the transport of Na + and K + by erythrocytes during the follicular and luteal phases of the human menstrual cycle, and in pregnant compared with non-pregnant women. Venous blood was drawn from 10 healthy...
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Clin Sci (Lond) (1992) 83 (3): 353–356.
Published: 01 September 1992
... have assessed whether oral administration of S -adenosyl- l -methionine to patients with hepatic disease can reverse the cholesterol enrichment of their erythrocytes. 2. The mean erythrocyte cholesterol-to-phospholipid molar ratio in 13 jaundiced patients was reduced 2 weeks after oral administration...
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Clin Sci (Lond) (1989) 76 (5): 559–563.
Published: 01 May 1989
...Dalila B. Corry; Michael L. Tuck; David B. N. Lee 1. Reduced Na + , K + pump activity has been reported in uraemic erythrocytes, and this has been attributed to the presence of a circulating ouabain-like inhibitor. Since we have previously reported marked suppression of Na + , K + co-transport...
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Clin Sci (Lond) (1989) 76 (4): 397–402.
Published: 01 April 1989
...–0.8 mmol/l. 2. We have measured cation transport in vivo after the administration of an oral load of rubidium chloride, and have found that, although intra-erythrocytic concentrations of rubidium were significantly lower 1 h after the administration of rubidium when the subjects were taking lithium...
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Clin Sci (Lond) (1987) 73 (2): 223–226.
Published: 01 August 1987
...J. C. Monaghan; D. A. Willcocks; M. J. Sinosich; G. S. Stokes 1. Studies of erythrocyte cation transport mechanisms in vitro were performed on eight normotensive, premenopausal female subjects at the mid-points of the follicular and luteal phases of their menstrual cycles. Concurrent plasma...
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Clin Sci (Lond) (1987) 72 (2): 171–179.
Published: 01 February 1987
...F. A. Khan; D. N. Baron 1. In hyperthyroidism, erythrocytes show decreased Na + ,K + -ATPase activity, decreased [ 3 H]ouabain binding capacity (an index of the number of sodium pumps) and decreased active sodium and potassium flux rates, with a high intracellular sodium concentration. 2...
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Clin Sci (Lond) (1985) 69 (6): 709–712.
Published: 01 December 1985
...Roberto Boero; Francesco Quarello; Cesare Guarena; Clelia Rosati; Giuseppe Piccoli 1. The effects of a 2 litre intravenous infusion of saline (0.9% NaCl solution) over 3 h on erythrocyte transmembrane sodium transport were studied in 12 normal human subjects. 2. After saline infusion a significant...
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Clin Sci (Lond) (1985) 69 (5): 613–624.
Published: 01 November 1985
...Ricardo P. Garay; Corinne Nazaret 1. Ouabain- and bumetanide-resistant (OBR) Na + efflux from human erythrocytes into a Mg 2+ -sucrose medium exhibits kinetic properties consistent with a transmembrane Na + leak. 2. In 52 essential hypertensive patients, the rate constant of Na + leak ( k e...
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Clin Sci (Lond) (1985) 68 (1): 29–33.
Published: 01 January 1985
... erythrocytes haemodialysis hyperparathyroidism 29 Association of secondary hyperparathyroidism with red cell survival in chronic haemodialysis patients D. SALTISSI A N D G . D. CARTER Deparrmenrs of Medicine and Chemical Parhology, Charing Ooss Hospital, London (Received 26 March129 June 1984; accepted I...
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Clin Sci (Lond) (1985) 68 (1): 45–47.
Published: 01 January 1985
...W. Zidek; H. Losse; H. Lange-Asschenfeldt; H. Vetter 1. In 25 patients with untreated essential hypertension and 25 healthy controls, erythrocyte intracellular Cl − concentration and activity as well as Na + activity were measured. 2. Intracellular Cl − concentration in essential hypertensive...
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Clin Sci (Lond) (1984) 67 (1): 111–115.
Published: 01 July 1984
... was determined in erythrocyte membranes of patients with essential hypertension and normal subjects, with a complementation assay in vitro. Fifteen normal subjects and 18 patients with essential hypertension (eight untreated and ten treated with β-adrenoreceptor blocking drugs alone or in combination with other...
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Clin Sci (Lond) (1984) 66 (4): 459–463.
Published: 01 April 1984
...Yu. V. Postnov; S. N. Orlov; M. B. Reznikova; G. G. Rjazhsky; N. I. Pokudin 1. The rate of calcium transport and calmodulin distribution in the erythrocytes of patients with essential hypertension were studied. In erythrocyte membranes subjected to calmodulin depletion by treatment with EGTA, both...
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Clin Sci (Lond) (1984) 66 (1): 55–62.
Published: 01 January 1984
...A. M. Peters; M. J. Walport; K. B. Elkon; H. J. Reavy; P. P. Ferjencik; J. P. Lavender; G. R. V. Hughes 1. The rate of clearance from blood of 111 In-labelled heat damaged autologous erythrocytes (HD-RBC) has been compared with that of simultaneously injected autologous 99m Tc-labelled erythrocytes...
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Clin Sci (Lond) (1983) 64 (2): 167–176.
Published: 01 February 1983
...M. Cumberbatch; D. B. Morgan 1. The erythrocyte content of sodium and of potassium were measured in 231 unselected patients with hypokalaemia, and together with net ouabain-sensitive sodium efflux in patients with severe hypokalaemia, before (20 patients) and during potassium repletion (14 patients...
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Clin Sci (Lond) (1982) 63 (s8): 27s–29s.
Published: 01 October 1982
...Y. Yamori; Y. Nara; T. Kanbe; H. Imafuku; K. Mori; M. Kihara; R. Horie 1. The membrane viscosity of erythrocytes and synaptosomal membranes from 3-month-old stroke-prone spontaneously hypertensive rats (SHRSP) was less than that of normotensive Wistar-Kyoto (WKY) rats. 2. The percentage...
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Clin Sci (Lond) (1982) 63 (s8): 41s–43s.
Published: 01 October 1982
...W. Zidek; H. Vetter; K.-G. Dorst; H. Zumkley; H. Losse 1. The intracellular Na + and Ca 2+ activity and Na + concentration were measured in erythrocytes of normotensive subjects, with and without a familial disposition to hypertension, in essential hypertensive patients with and without a family...
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Clin Sci (Lond) (1982) 63 (3): 281–284.
Published: 01 September 1982
...Sergei N. Orlov; Yuvenali V. Postnov 1. Ca 2+ -binding ability and membrane structure of red blood cells of patients with essential and renal hypertension were studied. 2. Ca 2+ -binding ability of the erythrocyte membrane of patients with essential hypertension was found to be reduced by 30...
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Clin Sci (Lond) (1982) 62 (5): 489–494.
Published: 01 May 1982
...R. Swaminathan; G. Clegg; M. Cumberbatch; Z. Zareian; F. McKenna 1. Erythrocyte sodium, sodium transport (ouabain-sensitive efflux rate of sodium, o M os Na , and ouabain-sensitive efflux rate constant of sodium, o M os Na ), sodium-potassium activated ouabain-sensitive adenosine triphosphatase (Na...
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Clin Sci (Lond) (1981) 61 (s7): 41s–43s.
Published: 01 December 1981
...W. Zidek; H. Vetter; H. Zumkley; H. Losse 1. The intracellular concentrations of Na + , K + and Ca 2+ were measured in the erythrocytes of spontaneously hypertensive rats and normotensive Wistar rats. 2. The intracellular Na + concentration in hypertensive rats was slightly elevated at 3.16 ± 0.25...
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Clin Sci (Lond) (1981) 61 (s7): 5s–10s.
Published: 01 December 1981
...D. C. Tosteson; N. Adragna; I. Bize; H. Solomon; M. Canessa erythrocytes leucocytes lithium—sodium cotransport ouabain-sensitive sodium—potassium pump sodium—potassium cotransport Clinical Science (1981) 5s-10s 5s STATE OF THE ART REVIEW Membranes, ions and hypertension D . C . T O S T E...
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Clin Sci (Lond) (1981) 61 (s7): 11s–12s.
Published: 01 December 1981
...N. Adragna; M. Canessa; I. Bize; H. Solomon; D. C. Tosteson 1. We describe in this paper a new ouabain-insensitive pathway for Na + and K + in human erythrocytes. K + efflux was measured in cells loaded by the p -chloromercuribenzene-sulphonate (PCMBS) procedure to contain approximately equal...
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Clin Sci (Lond) (1981) 61 (4): 391–397.
Published: 01 October 1981
...M. A. Mir 1. At a high dilution in Ringer solution (1:200), leukaemic plasma significantly ( P < 0.05) decreased the ouabain-sensitive and increased ouabain-insensitive components of sodium efflux from erythrocytes. At a low dilution (1:10) leukaemic plasma predominantly decreased the total...
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Clin Sci (Lond) (1981) 61 (3): 317–324.
Published: 01 September 1981
..., haemostatic variables, bleeding time and plasma vitamin A and carotene were studied. In seven subjects platelet aggregation induced by adenosine 5′-pyrophosphate (ADP) was also studied. 2. The proportions of 20:5ω3 and 22: 6ω3 in platelet and erythrocyte phosphoglycerides were substantially increased...
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Clin Sci (Lond) (1980) 59 (s6): 191s–193s.
Published: 01 December 1980
...R. P. Garay; G. Dagher; P. Meyer 1. In erythrocytes, the extrusion of a cell sodium load is accomplished by the ouabain-sensitive sodium-potassium pump and by the frusemide-sensitive sodium-potassium cotransport, which operate against the passive sodium permeability. All these three components...
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Clin Sci (Lond) (1980) 59 (s6): 195s–197s.
Published: 01 December 1980
...W. R. Fitzgibbon; T. O. Morgan; J. B. Myers 1. The rate constant for total 22 Na efflux from erythrocytes was examined in patients with mild to moderate hypertension and in normotensive controls. No difference in 22 Na efflux rate constant was found when the cells from both groups were incubated...
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Clin Sci (Lond) (1980) 59 (s6): 207s–209s.
Published: 01 December 1980
...S. N. Orlov; Yu. V. Postnov 1. The ability of isolated membrane fractions of cardiomyocytes, aortic smooth muscle and erythrocytes from spontaneously hypertensive rats to bind calcium was investigated isotopically. 2. Plasma membranes of aortic smooth muscle and erythrocytes of spontaneously...
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Clin Sci Mol Med (1978) 54 (6): 679–683.
Published: 01 June 1978
...B. A. Brooks; A. F. Lant 1. The Na + and Cl − transport systems of human erythrocytes have been compared for their sensitivities to diuretics known to act in the ascending limb of Henle's loop. In addition, chemical analogues of ‘loop’ compounds and also diuretics which act in other areas...
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Clin Sci Mol Med (1978) 54 (3): 251–256.
Published: 01 March 1978
...E. G. Astrup 1. Ten subjects with acute intermittent porphyria from three different families, and 92 relatives, were investigated for their erythrocyte uroporphyrinogen I synthase (EC 4.3.1.8) activities by the spectrofluorimetric method described and for their urinary concentrations of δ...