1-50 of 55
Keyword: erythrocytes
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Clin Sci (Lond) (1998) 94 (1): 43-48.
Published: 01 January 1998
...H. Hanssen; T. M. C. Brunini; M. Conway; A. P. Banning; N. B. Roberts; G. E. Mann; J. C. Ellory; A. C. Mendes Ribeiro 1. Transport of l-arginine was investigated under zero- trans conditions in human erythrocytes from healthy donors and patients with heart failure. 2. Saturable influx of l-arginine...
Articles
Clin Sci (Lond) (1998) 94 (1): 79-85.
Published: 01 January 1998
... fluorescent probes exploring either the outer membrane leaflet [trimethylamino-diphenylhexatriene (TMA-DPH)] or the lipid membrane core [diphenylhexatriene (DPH)], in platelets and erythrocytes of genetically hypertensive rats of the Prague hereditary hypertriglyceridaemic (HTG) strain. The relationships of...
Articles
Clin Sci (Lond) (1997) 93 (1): 57-64.
Published: 01 July 1997
...A. C. Mendes Ribeiro; H. Hanssen; K. Kiessling; N. B. Roberts; G. E. Mann; J. C. Ellory 1. Transport of l-arginine and the nitric oxide synthase inhibitors N G -monomethyl-l-arginine and N G -nitro-l-arginine was investigated in human erythrocytes from healthy donors and uraemic patients on...
Articles
Clin Sci (Lond) (1995) 88 (4): 405-412.
Published: 01 April 1995
...Alan Bevington; Dennis Brough; Frease E. Baker; Jane Hattersley; John Walls 1. During metabolic acidosis, significant fluxes of inorganic phosphate (P i ) may occur from cellular to extracellular fluid. In this study P i was measured in erythrocytes of uraemic patients before and after...
Articles
Clin Sci (Lond) (1994) 86 (1): 11-13.
Published: 01 January 1994
...Jaroslav Kuneš; Hassan Karama Bin Talib; Zdena DobešOvá; Antonín Vrána; Josef Zicha 1. Hypertension appears to be associated with both abnormalities in ion transport and disturbances in lipid metabolism. The aim of the present study was to search for alterations in erythrocyte ion transport in...
Articles
Clin Sci (Lond) (1993) 84 (4): 401-405.
Published: 01 April 1993
...G. D. Webb; G. G. Ashmead; S. Al-Mahdi; F. J. Auletta; M. K. McLaughlin 1. We have studied the transport of Na + and K + by erythrocytes during the follicular and luteal phases of the human menstrual cycle, and in pregnant compared with non-pregnant women. Venous blood was drawn from 10 healthy...
Articles
Clin Sci (Lond) (1992) 83 (3): 353-356.
Published: 01 September 1992
... have assessed whether oral administration of S -adenosyl- l -methionine to patients with hepatic disease can reverse the cholesterol enrichment of their erythrocytes. 2. The mean erythrocyte cholesterol-to-phospholipid molar ratio in 13 jaundiced patients was reduced 2 weeks after oral administration...
Articles
Clin Sci (Lond) (1992) 83 (2): 241-245.
Published: 01 August 1992
...A. Fabbri; R. Boero; E. Degli Esposti; C. Guarena; A. Lucatello; A. Sturani; G. Piccoli; M. Fusaroli 1. We evaluated the inheritance of erythrocyte Na + /Li + countertransport activity in IgA nephropathy by assessing this parameter in 19 patients with biopsy-proven IgA nephropathy and in their 53...
Articles
Clin Sci (Lond) (1992) 82 (5): 505-512.
Published: 01 May 1992
...G. S. Stokes; J. C. Monaghan; C. L. Flemming; H. Johnston; M. Jones; G. Pinkerton; R. Baber 1. Studies were undertaken in pre-menopausal women to examine the effects of treatment with standard oestrogen-progestogen and progestogen-only oral contraceptives on erythrocyte Na + ,K + co-transport and...
Articles
Clin Sci (Lond) (1990) 78 (2): 239-245.
Published: 01 February 1990
...Vanna Micheli; H. Anne Simmonds; Carlo Ricci 1. The synthesis of nicotinamide–adenine dinucleotide from nicotinamide and nicotinic acid was compared over different time scales at both physiological (0.7 μmol/l) and high (0.2–3 mmol/l) substrate concentrations in erythrocytes from three patients...
Articles
Clin Sci (Lond) (1989) 77 (4): 375-381.
Published: 01 October 1989
... erythrocytes were measured in plasma extracts from normal adults, hypertensive adults and neonates. 2. DLIS levels in neonate plasma extracts were significantly higher than those found for normotensive or hypertensive adults. No difference was observed between normotensive and hypertensive subjects. DLIS was...
Articles
Clin Sci (Lond) (1989) 76 (5): 559-563.
Published: 01 May 1989
...Dalila B. Corry; Michael L. Tuck; David B. N. Lee 1. Reduced Na + , K + pump activity has been reported in uraemic erythrocytes, and this has been attributed to the presence of a circulating ouabain-like inhibitor. Since we have previously reported marked suppression of Na + , K + co-transport...
Articles
Clin Sci (Lond) (1989) 76 (4): 397-402.
Published: 01 April 1989
...–0.8 mmol/l. 2. We have measured cation transport in vivo after the administration of an oral load of rubidium chloride, and have found that, although intra-erythrocytic concentrations of rubidium were significantly lower 1 h after the administration of rubidium when the subjects were taking lithium...
Articles
Clin Sci (Lond) (1989) 76 (1): 19-29.
Published: 01 January 1989
... concentrations of erythrocytes. 2. In control kidneys (total oxygen delivery approximately 32 μmol/min per kidney) no injury was seen in the medullary thick ascending limb of Henle's loop (MTAL) whilst 11 ± 5 ( sd )% of proximal tubules sustained damage. 3. Mild hypoxia (total oxygen delivery approximately 28...
Articles
Clin Sci (Lond) (1988) 75 (5): 477-480.
Published: 01 November 1988
...Kazushi Tsuda; Seiko Tsuda; Yohsuke Minatogawa; Hideo Iwahashi; Ryo Kido; Yoshiaki Masuyama 1. Membrane fluidity of erythrocytes and cultured vascular smooth muscle cells was studied in spontaneously hypertensive rats (SHR; Okamoto and Aoki strains) by means of an electron spin resonance (e.s.r...
Articles
Clin Sci (Lond) (1987) 73 (2): 223-226.
Published: 01 August 1987
...J. C. Monaghan; D. A. Willcocks; M. J. Sinosich; G. S. Stokes 1. Studies of erythrocyte cation transport mechanisms in vitro were performed on eight normotensive, premenopausal female subjects at the mid-points of the follicular and luteal phases of their menstrual cycles. Concurrent plasma...
Articles
Clin Sci (Lond) (1987) 72 (2): 171-179.
Published: 01 February 1987
...F. A. Khan; D. N. Baron 1. In hyperthyroidism, erythrocytes show decreased Na + ,K + -ATPase activity, decreased [ 3 H]ouabain binding capacity (an index of the number of sodium pumps) and decreased active sodium and potassium flux rates, with a high intracellular sodium concentration. 2. As...
Articles
Clin Sci (Lond) (1987) 72 (1): 103-112.
Published: 01 January 1987
... of the other 18 samples was 19 nmol/l ( sd = 10, range 6–36 nmol/l). 3. Salivary ALA was generally only 10–30% of the plasma level in normal and porphyric subjects. 4. Erythrocytes of normal and porphyric subjects contained no detectable ALA and were impermeable to its entry. 5. ALA clearance...
Articles
Clin Sci (Lond) (1986) 71 (6): 729-735.
Published: 01 December 1986
... observed in erythrocytes, from patients with these disorders, which were incubated in autologous plasma at 37°C, under an atmosphere of O 2 + CO 2 (95:5, v/v). However, chloride ions, which are transported passively across the cell membrane, showed no change in distribution between cells and plasma...
Articles
Clin Sci (Lond) (1986) 71 (5): 545-552.
Published: 01 November 1986
...Maurizio Trevisani; Natale De Santo; Martin Laurenzi; Michele Di Muro; Franco De Chiara; Maurizio Latte; Antonietta Franzese; Roberto Iacone; Giuseppe Capodicasa; Carmelo Giordano 1. The present report focuses on some aspects of the intra-erythrocytic cation metabolism (e.g. the maximal velocity of...
Articles
Clin Sci (Lond) (1985) 69 (6): 709-712.
Published: 01 December 1985
...Roberto Boero; Francesco Quarello; Cesare Guarena; Clelia Rosati; Giuseppe Piccoli 1. The effects of a 2 litre intravenous infusion of saline (0.9% NaCl solution) over 3 h on erythrocyte transmembrane sodium transport were studied in 12 normal human subjects. 2. After saline infusion a significant...
Articles
Clin Sci (Lond) (1985) 69 (5): 613-624.
Published: 01 November 1985
...Ricardo P. Garay; Corinne Nazaret 1. Ouabain- and bumetanide-resistant (OBR) Na + efflux from human erythrocytes into a Mg 2+ -sucrose medium exhibits kinetic properties consistent with a transmembrane Na + leak. 2. In 52 essential hypertensive patients, the rate constant of Na + leak ( k e ) was...
Articles
Clin Sci (Lond) (1985) 69 (5): 607-611.
Published: 01 November 1985
...Pietro Delva; Mario De Gasperi; Maurizio Degan; Grazia Covi; Alessandro Lechi 1. Outward bumetanide-sensitive Na + -K + co-transport was studied in the erythrocytes of 51 subjects, 24 normotensive subjects and 27 hypertensive patients, matched for sex and age. 2. Three kinetic parameters of this...
Articles
Clin Sci (Lond) (1985) 68 (5): 511-515.
Published: 01 May 1985
...N. A. Boon; C. Harper; J. K. Aronson; D. G. Grahame-Smith 1. We have measured intracellular sodium concentrations and specific 3 H-labelled glycoside binding characteristics in the erythrocytes and leucocytes of patients with untreated essential hypertension, and have compared the results with...
Articles
Clin Sci (Lond) (1985) 68 (1): 29-33.
Published: 01 January 1985
... erythrocytes haemodialysis hyperparathyroidism 29 Association of secondary hyperparathyroidism with red cell survival in chronic haemodialysis patients D. SALTISSI A N D G . D. CARTER Deparrmenrs of Medicine and Chemical Parhology, Charing Ooss Hospital, London (Received 26 March129 June 1984; accepted I...
Articles
Clin Sci (Lond) (1985) 68 (1): 45-47.
Published: 01 January 1985
...W. Zidek; H. Losse; H. Lange-Asschenfeldt; H. Vetter 1. In 25 patients with untreated essential hypertension and 25 healthy controls, erythrocyte intracellular Cl − concentration and activity as well as Na + activity were measured. 2. Intracellular Cl − concentration in essential hypertensive...
Articles
Clin Sci (Lond) (1984) 67 (1): 111-115.
Published: 01 July 1984
... was determined in erythrocyte membranes of patients with essential hypertension and normal subjects, with a complementation assay in vitro. Fifteen normal subjects and 18 patients with essential hypertension (eight untreated and ten treated with β-adrenoreceptor blocking drugs alone or in combination...
Articles
Clin Sci (Lond) (1984) 66 (4): 459-463.
Published: 01 April 1984
...Yu. V. Postnov; S. N. Orlov; M. B. Reznikova; G. G. Rjazhsky; N. I. Pokudin 1. The rate of calcium transport and calmodulin distribution in the erythrocytes of patients with essential hypertension were studied. In erythrocyte membranes subjected to calmodulin depletion by treatment with EGTA, both...
Articles
Clin Sci (Lond) (1984) 66 (1): 55-62.
Published: 01 January 1984
...A. M. Peters; M. J. Walport; K. B. Elkon; H. J. Reavy; P. P. Ferjencik; J. P. Lavender; G. R. V. Hughes 1. The rate of clearance from blood of 111 In-labelled heat damaged autologous erythrocytes (HD-RBC) has been compared with that of simultaneously injected autologous 99m Tc-labelled erythrocytes...
Articles
Clin Sci (Lond) (1983) 64 (3): 333-340.
Published: 01 March 1983
... xanthine and, in plasma, inosine. Erythrocyte hypoxanthine rose with the level in plasma, but there was no corresponding rise in IMP, the first intracellular metabolite of hypoxanthine. No rises in uridine or urate were found in plasma. 3. Plasma adenosine did not rise and fall significantly after exercise...
Articles
Clin Sci (Lond) (1983) 64 (2): 167-176.
Published: 01 February 1983
...M. Cumberbatch; D. B. Morgan 1. The erythrocyte content of sodium and of potassium were measured in 231 unselected patients with hypokalaemia, and together with net ouabain-sensitive sodium efflux in patients with severe hypokalaemia, before (20 patients) and during potassium repletion (14 patients...
Articles
Clin Sci (Lond) (1983) 64 (2): 177-182.
Published: 01 February 1983
...E. Jill Rubython; D. B. Morgan 1. The sodium content, the ouabain-sensitive sodium efflux and efflux rate constant and the ouabain-binding capacity were measured in the erythrocytes of 53 patients with hypokalaemia and in 37 healthy controls. The sodium content alone was measured in a further 57...
Articles
Clin Sci (Lond) (1982) 63 (s8): 27s-29s.
Published: 01 October 1982
...Y. Yamori; Y. Nara; T. Kanbe; H. Imafuku; K. Mori; M. Kihara; R. Horie 1. The membrane viscosity of erythrocytes and synaptosomal membranes from 3-month-old stroke-prone spontaneously hypertensive rats (SHRSP) was less than that of normotensive Wistar-Kyoto (WKY) rats. 2. The percentage...
Articles
Clin Sci (Lond) (1982) 63 (s8): 41s-43s.
Published: 01 October 1982
...W. Zidek; H. Vetter; K.-G. Dorst; H. Zumkley; H. Losse 1. The intracellular Na + and Ca 2+ activity and Na + concentration were measured in erythrocytes of normotensive subjects, with and without a familial disposition to hypertension, in essential hypertensive patients with and without a family...
Articles
Clin Sci (Lond) (1982) 63 (3): 281-284.
Published: 01 September 1982
...Sergei N. Orlov; Yuvenali V. Postnov 1. Ca 2+ -binding ability and membrane structure of red blood cells of patients with essential and renal hypertension were studied. 2. Ca 2+ -binding ability of the erythrocyte membrane of patients with essential hypertension was found to be reduced by 30...
Articles
Clin Sci (Lond) (1982) 62 (5): 489-494.
Published: 01 May 1982
...R. Swaminathan; G. Clegg; M. Cumberbatch; Z. Zareian; F. McKenna 1. Erythrocyte sodium, sodium transport (ouabain-sensitive efflux rate of sodium, o M os Na , and ouabain-sensitive efflux rate constant of sodium, o M os Na ), sodium-potassium activated ouabain-sensitive adenosine triphosphatase (Na...
Articles
Clin Sci (Lond) (1982) 62 (1): 101-107.
Published: 01 January 1982
...P. A. Jackson; D. B. Morgan 1. The cholesterol and phospholipid content of the cell membrane and the efflux of sodium were measured in the erythrocytes of patients with chronic cholestasis and in healthy subjects. 2. The membranes from the patients contained more cholesterol and phospholipid and...
Articles
Clin Sci (Lond) (1981) 61 (6): 757-764.
Published: 01 December 1981
...M. A. Mansell; J. Allsop; M. E. North; R. J. Simmonds; R. A. Harkness; R. W. E. Watts 1. We have studied purine metabolism in renal failure using high-pressure liquid chromatography to determine metabolite concentrations in erythrocytes and plasma, and microradiochemical assays of enzyme activity...
Articles
Clin Sci (Lond) (1981) 61 (4): 391-397.
Published: 01 October 1981
...M. A. Mir 1. At a high dilution in Ringer solution (1:200), leukaemic plasma significantly ( P < 0.05) decreased the ouabain-sensitive and increased ouabain-insensitive components of sodium efflux from erythrocytes. At a low dilution (1:10) leukaemic plasma predominantly decreased the total and...
Articles
Clin Sci (Lond) (1981) 61 (3): 317-324.
Published: 01 September 1981
..., haemostatic variables, bleeding time and plasma vitamin A and carotene were studied. In seven subjects platelet aggregation induced by adenosine 5′-pyrophosphate (ADP) was also studied. 2. The proportions of 20:5ω3 and 22: 6ω3 in platelet and erythrocyte phosphoglycerides were substantially increased by the...
Articles
Clin Sci (Lond) (1981) 61 (s7): 41s-43s.
Published: 01 January 1981
...W. Zidek; H. Vetter; H. Zumkley; H. Losse 1. The intracellular concentrations of Na + , K + and Ca 2+ were measured in the erythrocytes of spontaneously hypertensive rats and normotensive Wistar rats. 2. The intracellular Na + concentration in hypertensive rats was slightly elevated at 3.16 ± 0.25...
Articles
Clin Sci (Lond) (1981) 61 (s7): 5s-10s.
Published: 01 January 1981
...D. C. Tosteson; N. Adragna; I. Bize; H. Solomon; M. Canessa © 1981 The Biochemical Society and the Medical Research Society 1981 erythrocytes leucocytes lithium—sodium cotransport ouabain-sensitive sodium—potassium pump sodium—potassium cotransport Clinical Science (1981) 5s-10s 5s...
Articles
Clin Sci (Lond) (1981) 61 (s7): 11s-12s.
Published: 01 January 1981
...N. Adragna; M. Canessa; I. Bize; H. Solomon; D. C. Tosteson 1. We describe in this paper a new ouabain-insensitive pathway for Na + and K + in human erythrocytes. K + efflux was measured in cells loaded by the p -chloromercuribenzene-sulphonate (PCMBS) procedure to contain approximately equal...
Articles
Clin Sci (Lond) (1980) 59 (s6): 191s-193s.
Published: 01 January 1980
...R. P. Garay; G. Dagher; P. Meyer 1. In erythrocytes, the extrusion of a cell sodium load is accomplished by the ouabain-sensitive sodium-potassium pump and by the frusemide-sensitive sodium-potassium cotransport, which operate against the passive sodium permeability. All these three components of...
Articles
Clin Sci (Lond) (1980) 59 (s6): 195s-197s.
Published: 01 January 1980
...W. R. Fitzgibbon; T. O. Morgan; J. B. Myers 1. The rate constant for total 22 Na efflux from erythrocytes was examined in patients with mild to moderate hypertension and in normotensive controls. No difference in 22 Na efflux rate constant was found when the cells from both groups were incubated in...
Articles
Clin Sci (Lond) (1980) 59 (s6): 207s-209s.
Published: 01 January 1980
...S. N. Orlov; Yu. V. Postnov 1. The ability of isolated membrane fractions of cardiomyocytes, aortic smooth muscle and erythrocytes from spontaneously hypertensive rats to bind calcium was investigated isotopically. 2. Plasma membranes of aortic smooth muscle and erythrocytes of spontaneously...
Articles
Clin Sci Mol Med (1978) 54 (6): 679-683.
Published: 01 June 1978
...B. A. Brooks; A. F. Lant 1. The Na + and Cl − transport systems of human erythrocytes have been compared for their sensitivities to diuretics known to act in the ascending limb of Henle's loop. In addition, chemical analogues of ‘loop’ compounds and also diuretics which act in other areas of the...
Articles
Clin Sci Mol Med (1978) 54 (3): 251-256.
Published: 01 March 1978
...E. G. Astrup 1. Ten subjects with acute intermittent porphyria from three different families, and 92 relatives, were investigated for their erythrocyte uroporphyrinogen I synthase (EC 4.3.1.8) activities by the spectrofluorimetric method described and for their urinary concentrations of δ...
Articles
Clin Sci Mol Med (1977) 52 (5): 463-467.
Published: 01 May 1977
...T. K. With 1. A simple chromatographic method for the study of porphyrins in erythrocytes and blood plasma, requiring little technician time, is described. The findings in adults and neonates are presented as well as those from severely ill patients. 2. The regular occurrence of uro-, copro- and...
Articles
Clin Sci Mol Med (1976) 51 (2): 189-196.
Published: 01 August 1976
...J. M. Bone; A. Verth; Anne T. Lambie 1. Intracellular hydrogen ion activity, [H + ] i , was estimated in human erythrocytes and in nucleated avian erythrocytes from measurements of the distribution of ammonia and 5,5′-dimethyloxazolidine-2,4′-dione (DMO) between intracellular and extracellular...