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Keywords: erythropoietin
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Clin Sci (Lond) (2018) 132 (18): 2071–2085.
Published: 22 September 2018
... of renal function including reductions in both glomerular filtration rate (GFR) and tubular handling of water and solutes. Although obstruction can be released by surgical operation, the child will suffer from diuresis for sometime. It has been reported that erythropoietin (EPO) could prevent the down...
Includes: Supplementary data
Clin Sci (Lond) (2012) 122 (7): 329–336.
Published: 07 December 2011
...Lindsey Tilling; Joanne Hunt; Ann Donald; Brian Clapp; Phil Chowienczyk Vasoprotective effects of erythropoietin in animal models are mediated by endothelium-derived NO and/or mobilization of EPCs (endothelial progenitor cells) and may be enhanced by ischaemia: whether they are present in humans...
Clin Sci (Lond) (2002) 103 (s2002): 44S–47S.
Published: 01 September 2002
...Torsten SLOWINSKI; Norma SCHULZ; Frank T. RUSCHITZKA; Thomas QUASCHNING; Christian BAUER; Franz THEURING; Hans-H. NEUMAYER; Max GASSMANN; Berthold HOCHER Transgenic overexpression of erythropoietin (Epo) in mice increases haematocrit to a mean of 80% in adult mice, leading to an increase in blood...
Clin Sci (Lond) (2002) 103 (3): 275–282.
Published: 14 August 2002
...M. BUEMI; E. CAVALLARO; F. FLOCCARI; A. STURIALE; C. ALOISI; M. TRIMARCHI; G. GRASSO; F. CORICA; N. FRISINA It is now widely known that erythropoietin (Epo) does not only affect the haematopoietic system, but it can be considered a multifunctional trophic factor with an effect on the general...
Clin Sci (Lond) (1999) 97 (6): 639–647.
Published: 29 October 1999
...Xiao Chun WU; Nicholas T. RICHARDS; Edward J. JOHNS This study investigated potential reasons why erythropoietin (EPO) given therapeutically to patients with renal failure may increase peripheral, but not renal, vascular resistance. This was done by comparing the effects of EPO on resting tension...
Clin Sci (Lond) (1999) 97 (4): 413–419.
Published: 24 August 1999
...Xiao Chun WU; Edward J. JOHNS; Nicholas T. RICHARDS We have investigated the effects of recombinant human erythropoietin (EPO) on the responses of rat renal arcuate arteries to dopamine, noradrenaline and acetylcholine and on the release of NO from human umbilical vein endothelial cells (HUVEC...
Clin Sci (Lond) (1994) 86 (5): 633–638.
Published: 01 May 1994
...Felix Stockenhuber; Michaela Keil; Christian Wurnig; Robert W. Kurz; Michael Gottsauner-Wolf; Peter Balcke 1. Serum levels of erythropoietin and the immune parameters tumour necrosis factor-α, soluble interleukin-2 receptor, interleukin-2, interleukin-6 and interferon-γ were measured in patients...
Clin Sci (Lond) (1993) 84 (4): 441–447.
Published: 01 April 1993
...Peter Báaráany; Ulla Freyschuss; Erna Pettersson; Jonas Bergström 1. The effects of correcting anaemia on exercise capacity were evaluated in 21 haemodialysis patients (aged 39 ± 12 years) before starting treatment with recombinant human erythropoietin (Hb concentration, 73 ± 10 g/l; total Hb, 59...
Clin Sci (Lond) (1993) 84 (3): 319–324.
Published: 01 March 1993
...Michael F. Fitzpatrick; Tom MacKay; Kenneth F. Whyte; Martin Allen; Robert C. Tam; Caroline J. Dore; Michael Henley; P. Mary Cotes; Neil J. Douglas 1. To clarify the relationship between nocturnal oxygen desaturation and erythropoietin production in patients with chronic obstructive pulmonary...
Clin Sci (Lond) (1993) 84 (1): 47–50.
Published: 01 January 1993
...Kazuhiro Takahashi; Kazuhito Totsune; Yutaka Imai; Masahiko Sone; Mitsuru Nozuki; Osamu Murakami; Hiroshi Sekino; Toraichi Mouri 1. Elevation of blood pressure is one of the major side effects of recombinant human erythropoietin therapy in haemodialysis patients. 2. We investigated the possible...
Clin Sci (Lond) (1992) 83 (4): 453–459.
Published: 01 October 1992
...Chunlong Huang; Gerard Davis; Edward J. Johns 1. Studies were undertaken to examine the effect of acute and chronic administration of human recombinant erythropoietin on kidney cortical and papillary perfusion in the anaesthetized rat using laser-Doppler flowmetry. 2. Thirty minutes after...
Clin Sci (Lond) (1992) 82 (2): 119–126.
Published: 01 February 1992
... concentrations, plasma renin activity and serum erythropoietin concentration remained unchanged. 4. The sensitivity of the renal allograft to plasma atrial natriuretic factor concentrations in the high physiological range suggests a role for endogenous atrial natriuretic factor in the modulation of graft...
Clin Sci (Lond) (1991) 81 (5): 645–653.
Published: 01 November 1991
...Peter Bárány; Rolf Wibom; Eric Hultman; Jonas Bergström 1. The ATP production rate in isolated skeletal muscle mitochondria was measured with a bioluminescence method, before and during erythropoietin treatment, in 21 anaemic haemodialysis patients. In addition, the concentrations of ATP...
Clin Sci (Lond) (1991) 81 (1): 113–121.
Published: 01 July 1991
...Sergio De Marchi; Emanuela Cecchin 1. A randomized, partial-crossover study was conducted in uraemic patients with dialysis-associated anaemia and transfusional iron overload to evaluate the effects of desferrioxamine chelation therapy and of recombinant human erythropoietin treatment on hepatic...
Clin Sci (Lond) (1987) 73 (6): 665–667.
Published: 01 December 1987
... is usually performed for excessive secondary polycythaemia in man. Our results suggest a possible therapeutic role for verapamil in such individuals. 01 4 1987 12 6 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 erythropoietin hypoxia polycythaemia...
Clin Sci (Lond) (1985) 69 (4): 413–422.
Published: 01 October 1985
... with chronic airflow obstruction and polycythaemia and 19 normal controls. 2. Estimates of serum immunoreactive erythropoietin (siEp) in those without polycythaemia were 19 m-i.u./ml (geometric mean) with 95% confidence range 11–35 m-i.u./ml and stable during 3 months. In those with polycythaemia they were...