...Zhipeng Tao; Zhiyong Cheng Hormonal signaling plays key roles in tissue and metabolic homeostasis. Accumulated evidence has revealed a great deal of insulin and estrogen signaling pathways and their interplays in the regulation of mitochondrial, cellular remodeling, and macronutrient metabolism...

... surgery or trauma. Estrogen exerts salutary effect on intestinal I/R injury, but the receptor type is not totally understood. We aimed to identify whether the G protein–coupled estrogen receptor (GPER) could protect the intestine against I/R injury and explored the mechanism. Adult male C57BL/6 mice were...

... © 2016 Authors; published by Portland Press Limited 2016 arrhythmia estrogen heart hypertrophy ion channels repolarization The simple deflections of the human electrocardiogram (ECG) obscure the fact that they are the result of the movement of trillions of ions across the cell...