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Keywords: ethanol
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Clin Sci (Lond) (2001) 101 (3): 253–260.
Published: 03 August 2001
...Massimiliano FAZIO; Moreno BARDELLI; Loredana MACALUSO; Fabio FIAMMENGO; Piero Luigi MATTEI; Monica BOSSI; Bruno FABRIS; Fabio FISCHETTI; Lorenzo PASCAZIO; Riccardo CANDIDO; Renzo CARRETTA The effects of ethanol administered orally (300 mg/kg in 250 ml of water) or intravenously (7.5 mg·min -1 ·kg...
Clin Sci (Lond) (2000) 98 (4): 401–407.
Published: 08 March 2000
...Leanne M. D. DELBRIDGE; Pamela J. CONNELL; Peter J. HARRIS; Trefor O. MORGAN Little is known about the direct cardiac effects of socially common sub-intoxication levels of ethanol. Previous studies evaluating the responses of normal cardiomyocytes to short-term ethanol exposure have utilized...
Clin Sci (Lond) (1994) 87 (4): 441–446.
Published: 01 October 1994
... that enhanced hepatic fatty acid synthesis does not occur in rats fed alcohol and a low-fat diet for 4 weeks, and is thus not implicated in the pathogenesis of alcohol-induced fatty liver. © 1994 The Biochemical Society and the Medical Research Society 1994 acetyl-CoA carboxylase ethanol fatty liver...
Clin Sci (Lond) (1992) 82 (4): 433–438.
Published: 01 April 1992
...M. A. Manso; H. A. Gallego; I. de Dios 1. The effects of a diet rich in protein and fat, compared with a control diet, with or without chronic ingestion of ethanol on the pancreatic response to cholecystokinin were studied in rats after a 7-month treatment period. The acute effects of intraduodenal...
Clin Sci (Lond) (1990) 79 (5): 451–456.
Published: 01 November 1990
...V. Barrios; M. N. Rodríguez-Sánchez; E. Arilla 1. Acute ethanol administration resulted in an increase in the total number of specific somatostatin receptors in rat frontoparietal cortex and hippocampus, and a decrease in the level of somatostatin-like immuno-reactivity in the hippocampus...
Clin Sci (Lond) (1990) 78 (2): 235–238.
Published: 01 February 1990
...J. Main; T. Thomas 1. Although ethanol appears to alter cellular sodium transport, the exact nature of its effects has not been clearly defined. We have studied the effects of different concentrations of ethanol on human leucocyte sodium content, and on the rise in leucocyte sodium content which...
Clin Sci (Lond) (1988) 75 (2): 135–142.
Published: 01 August 1988
... in nine normolipidaemic subjects, in whom a hypertriglyceridaemic state was induced by the acute administration of ethanol (40 g) plus fat (70 g) or of fat only. 2. Triglyceride (TG) levels increased by 180% 4–6 h after fat plus ethanol intake, the hypertriglyceridaemic response being inversely correlated...
Clin Sci (Lond) (1988) 74 (5): 461–466.
Published: 01 May 1988
...Victor R. Preedy; Timothy J. Peters 1. The effects of a single dose of ethanol (75 mmol/kg body weight) on rates of muscle protein synthesis were examined in young rats. Fractional rates of protein synthesis were measured in the soleus, plantaris, gastrocnemius, diaphragm and stomach by the large...
Clin Sci (Lond) (1988) 74 (4): 407–412.
Published: 01 April 1988
... and sterol synthesis in liver of alcohol-fed rats. 15 9 1987 1 10 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 cholesterol synthesis esterified and non-esterified cholesterol ethanol fatty acid synthesis fatty liver Clinical Science (1988) 74,407-412...
Clin Sci (Lond) (1987) 73 (4): 387–393.
Published: 01 October 1987
...Rachel J. Green; D. N. Baron 1. Acute ethanol consumption in human volunteers did not appear to alter active cation fluxes by Na + ,K + -ATPase, or intracellular electrolyte concentrations, in peripheral leucocytes or erythrocytes. 2. Urinary electrolyte excretion was decreased after ethanol...
Clin Sci (Lond) (1987) 73 (2): 159–163.
Published: 01 August 1987
...S. Venkatesan; R. J. Ward; T. J. Peters 1. Liver slices from chronically alcohol-fed rats incubated with 3 H 2 O showed less than half the fatty acid synthesis rates of pair-fed controls. Addition of 50 mmol/l ethanol or of 10 mmol/l lactate and 1 mmol/l pyruvate to the incubation medium did...
Clin Sci (Lond) (1987) 72 (2): 251–254.
Published: 01 February 1987
...G. Eisenhofer; D. G. Lambie; R. H. Johnson 1. We examined the acute effects of ethanol consumption on circulatory responses to the cold pressor test, to handgrip exercise and to intravenous infusion of methoxamine in eight normal male subjects. 2. Ethanol consumption reduced systolic blood pressure...
Clin Sci (Lond) (1987) 72 (1): 113–122.
Published: 01 January 1987
...A.-R. A. Abdel-Rahman; R. H. Merrill; W. R. Wooles 1. The effects of acute ethanol administration on blood pressure, heart rate and the baroreceptor reflex control of heart rate were studied in normotensive subjects who served as their own control. Baroreceptor reflex control of heart rate...
Clin Sci (Lond) (1986) 70 (3): 295–299.
Published: 01 March 1986
... between erythrocyte and hepatic cytosolic aldehyde dehydrogenase activity in the control group ( r = 0.94, P < 0.05) but not in the other study groups. acetaldehyde alcoholic liver disease aldehyde dehydrogenase activity erythrocyte ethanol © 1986 The Biochemical Society and the Medical...
Clin Sci (Lond) (1985) 69 (5): 517–523.
Published: 01 November 1985
... ethanol fatty liver lipase triglyceride Clinical Science (1985) 69, 517-523 517 Activities and subcellular distributions of hepatic lipases in control subjects and in patients with alcoholic fatty liver NANCY N . Y. LEUNG, STUART R . CAIRNS A N D TIMOTHY J . PETERS Division of Clinical Cell Biology...
Clin Sci (Lond) (1984) 67 (4): 397–401.
Published: 01 October 1984
...M. J. P. Arthur; A. Lee; R. Wright 1. Blood ethanol and acetaldehyde concentrations were compared in normal young male and female subjects after intravenous infusion of 0.5 g of ethanol/kg body weight. 2. After the infusion was completed, females had significantly higher mean concentrations...
Clin Sci (Lond) (1984) 66 (6): 733–739.
Published: 01 June 1984
...I. W. Fellows; I. A. MacDonald; T. Bennett 1. Ten healthy male subjects ingested ethanol (BP; 0.5 g/kg body weight) after an overnight fast, on two separate occasions, at environmental temperatures of either 21°C or 3O°C. 2. The mean maximal fall in deep body temperature was not significantly...
Clin Sci (Lond) (1983) 64 (5): 555–557.
Published: 01 May 1983
...Jon G. Ayres; T. J. H. Clark 1. The effect of intravenous infusions of saline, and 2, 4 and 8% (v/v in saline) ethanol on airflow were assessed in five normal male subjects and five male patients with asthma. 2. Normal subjects showed no response to intravenous ethanol at any dose. 3. in patients...
Clin Sci (Lond) (1982) 63 (5): 441–445.
Published: 01 November 1982
...A. W. Jones 1. Ten healthy men each drank a moderate dose of ethanol in experiments to test if the temperature and moisture content of inhaled air could alter the concentration of ethanol in exhaled breath. 2. They breathed air at various temperatures and relative humidities (RH) for about 1 min...
Clin Sci (Lond) (1981) 61 (2): 129–133.
Published: 01 August 1981
...D. N. Brindley © 1981 The Biochemical Society and the Medical Research Society 1981 atherosclerosis diabetes diet ethanol fatty liver fructose glucocorticoids insulin lipid metabolism lipoprotein lipase lipoproteins obesity l-α-phosphatidate phosphohydrolase sorbitol stress...
Clin Sci (Lond) (1979) 56 (6): 563–573.
Published: 01 June 1979
...H. B. Stoner; K. N. Frayn; R. N. Barton; C. J. Threlfall; R. A. Little 1. The plasma concentrations of glucose, lactate, amino acids, non-esterified fatty acids, glycerol, ketone bodies, ethanol, cortisol and insulin were measured in patients within a few hours of injury and before treatment...
Clin Sci (Lond) (1979) 56 (3): 283–286.
Published: 01 March 1979
...K. E. L. McColl; B. Whiting; M. R. Moore; A. Goldberg 1. The concentrations of ethanol in blood, mixed saliva obtained before and after rinsing and drying the mouth and parotid saliva have been monitored in 12 healthy subjects after the ingestion of alcohol. 2. A highly significant linear...
Clin Sci Mol Med (1978) 55 (4): 383–389.
Published: 01 October 1978
... Society 1978 alcoholic liver disease enzymes ethanol lysosomes microsomes mitochondria subcellular fractionation plasma membrane Clinical Science and Molecular Medicine (1978) 55, 383-389 Changes in hepatic enzymes and organelles in alcoholic liver disease C A R O L A. S E Y M O U R * A N...
Clin Sci Mol Med (1978) 55 (4): 341–347.
Published: 01 October 1978
...L. A. Videla 1. The administration of a single oral dose of 2, 3, 4 or 5 g of ethanol/kg (43.5, 65.2, 87.0 or 108.7 mmol/kg respectively) to rats increases the rate of oxygen consumption by liver slices from animals killed 24–48 h later. 2. The increase in the rate of hepatic respiration can...
Clin Sci Mol Med (1978) 55 (1): 57–61.
Published: 01 July 1978
...J.E.F. Pohl 1. The cerebral depressant effect of 30 ml of aqueous ethanol diluted to 25% and administered orally to 16 volunteer subjects was compared with a control group of 15 volunteer subjects. 2. The two parallel forms of the Watson-Glaser Critical Thinking Appraisal tests were employed...
Clin Sci Mol Med (1977) 53 (3): 205–214.
Published: 01 September 1977
...A. Juhlin-Dannfelt; L. Jorfeldt; L. Hagenfeldt; B. Hulten 1. The influence of ethanol administration on the metabolism of non-esterified fatty acids (NEFA) and on the utilization of blood-borne substrates and stored glycogen by leg muscles was examined in nine young healthy subjects at rest...
Clin Sci Mol Med (1977) 52 (2): 219–222.
Published: 01 February 1977
...A. R. Marsh; H. S. Fraser; A. Breckenridge; B. Lewis; G. R. Thompson 1. Four groups of rats received a liquid formula diet, given alone (control), or supplemented with either ethanol or phenobarbitone, or both together. 2. The ethanol-treated group showed a fall in plasma triglyceride and a rise...
Clin Sci Mol Med (1975) 49 (1): 33–38.
Published: 01 July 1975
...S. A. Sahn; S. Lakshminarayan; D. J. Pierson; J. V. Weil 1. Hypoxic and hypercapnic ventilatory drives were measured in eight healthy male subjects before and after ingestion of ethanol, in a dose of 17 mmol/kg body weight. 2. A significant decrease in hypoxic ventilatory drive was observed at 20...
Clin Sci Mol Med (1975) 48 (5): 453–455.
Published: 01 May 1975
...C. R. Nair; O. P. Nirankari; P. N. Chhuttani; D. V. Datta 1. The mechanism of development of acute alcoholic fatty liver in the Rhesus monkey was investigated by studying the effect of Triton WR-1339 on plasma triglycerides. 2. After ethanol infusion, the rise in plasma triglyceride produced...
Clin Sci Mol Med (1975) 48 (2): 153–156.
Published: 01 February 1975
...Y. Giudicelli; R. Nordmann; J. Nordmann 1. The oral administration of propan-2-ol [isopropanol; 100 mmol (6 g)/kg body weight] or ethanol [130 mmol (6 g)/kg body weight] to starved rats produced no change in plasma post-heparin lipase activity (PHLA) compared with that observed in 154 mmol/l sodium...
Clin Sci Mol Med (1974) 47 (6): 639–642.
Published: 01 December 1974
...R. Lindsay 1. HeLa cells from human cervix and L cells from mouse fibroblasts were cultured in the presence and absence of ethanol. 2. Ethanol produced an increase in the sodium-plus-potassium-ion-stimulated adenosine triphosphatase (Na-ATPase). 3. This effect was inhibited by cycloheximide. 4...
Clin Sci Mol Med (1973) 45 (4): 527–531.
Published: 01 October 1973
.... The subjects were retested after consumption of 1 ml of ethanol/kg body weight. Coughing was significantly suppressed in nine of the ten subjects. 2. The marked suppression of the cough reflex by the moderate amounts of ethanol used in this study provides confirmatory evidence for the suspected causal links...
Clin Sci Mol Med (1973) 44 (5): 505–510.
Published: 01 May 1973
...C. R. Nair; S. Saha; R. N. Chakravarti; P. N. Chhuttani; D. V. Datta 1. The effect of intravenous infusion of ethanol on the concentration of plasma free fatty acids (FFA) and triglycerides (TG) and on hepatic triglyceride content was studied in Rhesus monkeys. 2. A minor fall in the plasma FFA...
Clin Sci (1972) 42 (6): 781–784.
Published: 01 June 1972
...Maureen O'keane; M. R. Moore; A. Goldberg 1. Because it has been shown that a majority of alcoholics are subclinically scorbutic, the metabolism of ethanol was studied in subclinically-scorbutic guinea-pigs. 2. Hepatic alcohol dehydrogenase activity was raised maximally by ethanol within 2 days. 3...