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Songtao Cheng, Gang Wang, Yejinpeng Wang, Liwei Cai, Kaiyu Qian, Lingao Ju, Xuefeng Liu, Yu Xiao, Xinghuan Wang
Clin Sci (Lond) (2019) 133 (15): 1745–1758.
Published: 07 August 2019
... increased in BCa compared with paracancerous tissues. Inhibition of fatty acid oxidation (FAO) with etomoxir caused lipid accumulation, decreased adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide phosphate (NADPH) levels, suppressed BCa cell growth in vitro and in vivo , and reduced...
Includes: Supplementary data
Christian J. F. Holubarsch, Martin Rohrbach, Matthias Karrasch, Erich Boehm, Lech Polonski, Piotr Ponikowski, Siegfried Rhein
Clin Sci (Lond) (2007) 113 (4): 205–212.
Published: 13 July 2007
...Christian J. F. Holubarsch; Martin Rohrbach; Matthias Karrasch; Erich Boehm; Lech Polonski; Piotr Ponikowski; Siegfried Rhein Etomoxir is an inhibitor of mitochondrial CPT1 (carnitine palmitoyltransferase 1) and thereby switches energy metabolism from fatty acids to glucose oxidation. Such a...
Clin Sci (Lond) (2000) 99 (1): 27–35.
Published: 06 June 2000
... key protein in calcium cycling, i.e. the sarcoplasmic reticulum Ca 2+ -ATPase, and of the α-myosin heavy chain have been shown to be enhanced by treatment with etomoxir, a carnitine palmitoyltransferase inhibitor, in normal and pressure-overloaded rat myocardium. We therefore studied, for the first...