... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bone marrow mesenchymal stem cell exosome microRNA-122-5p osteonecrosis...

[email protected] ) 17 10 2022 15 02 2023 20 02 2023 biodistribution exosome extracellular vesicle microparticles placenta pregnancy Human pregnancy is characterized by systemic alterations to the cardiovascular system, including a 30–50% increase in cardiac output and reduced...

.../20013078.2018.1535750 7. Mincheva-Nilsson L. ( 2021 ) Immunosuppressive protein signatures carried by syncytiotrophoblast-derived exosomes and their role in human pregnancy . Front. Immunol. 12 , 717884 34381459 10.3389/fimmu.2021.717884 8. James-Allan L.B. and Devaskar S.U...

...He Liu; Yanlong Liu; Ping Sun; Kaiming Leng; Yi Xu; Liqi Mei; Peng Han; Bomiao Zhang; Kefei Yao; Chunbo Li; Junge Bai; Binbin Cui Cancer-derived exosomal miRNAs play an important role in the development of metastasis, but the effects and underlying mechanisms remain unclear. In the present study...

... verified that inhibition of circFMN2 decreased hTERT expression. Importantly, we demonstrated that circFMN2 was up-regulated in serum exosomes from CRC patients. Conclusion: In conclusion, circFMN2 is a central component linking circRNAs to progression of CRC via an miR-1182/hTERT axis. Correspondence...

.... In this work, the expression of circular RNA circ-0000284 (aka circHIPK3) was specifically elevated in CCA cell lines, human tumor tissues and plasma exosomes. Gain and loss of function approaches were performed to better understand the molecular mechanisms regulated by circ-0000284. Notably, the authors...

...) through cell transplantation. The current study aims to explore the role of bone marrow (BM) MSCs (BMSCs)-derived exosomes carrying microRNA-122-5p (miR-122-5p) in ONFH rabbit models. First, rabbit models with ONFH were established. ONFH-related miRNAs were screened using the Gene Expression Omnibus (GEO...

... and potential molecular mechanisms. Through utilizing clinical samples and high fat diet-fed mice, we investigated the physiological roles of miR-122 in obesity-related cardiomyopathy. Besides, present study explored the mitochondrial function under exosomal miR-122 stimulation in mouse primary cardiomyocytes...

... that inhibition of circRASSF2 decreased IGF-1R expression. Furthermore, silencing circRASSF2 suppressed LSCC growth in vivo . Importantly, we demonstrated that circRASSF2 was up-regulated in serum exosomes from LSCC patients. Altogether, silencing circRASSF2 suppresses progression of LSCC by interacting with miR...