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Keywords: fatty acid
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Clin Sci (Lond) (2015) 128 (6): 349–355.
Published: 28 November 2014
...Michael F. Oliver Plasma free fatty acids (non-esterified fatty acids) increase in the first hour of the onset of acute myocardial ischaemia. This results from catecholamine stimulation of adipose tissue lipolysis. It can lead to a metabolic crisis in the injured myocardium with the development...
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Clin Sci (Lond) (2009) 116 (3): 205–218.
Published: 08 January 2009
... we describe the rationale behind drug design strategies targeting PPARγ, based on current knowledge regarding the effects of such drugs in experimental animal models, as well as in clinical practice. Regarding endogenous PPARγ ligands, several fatty acid derivatives bind PPARγ with different...
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Clin Sci (Lond) (2009) 116 (2): 113–123.
Published: 15 December 2008
.... Correspondence: Mrs Margaret J. Hill (email margaret.hill@warwick.ac.uk ). 19 2 2008 14 5 2008 5 6 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 cardiovascular disease fatty acid obesity triacylglycerol Type 2 diabetes Obesity, diabetes and CVD...
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Clin Sci (Lond) (2008) 115 (1): 1–12.
Published: 02 June 2008
.... Correspondence: Dr Paola Loria (email loria.paola@unimore.it ). 4 9 2007 13 11 2007 21 12 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 atherosclerosis cardiovascular disease energy homoeostasis fatty acid metabolic syndrome non-alcoholic fatty liver...
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Clin Sci (Lond) (2007) 113 (2): 65–77.
Published: 13 June 2007
...Thais Martins de Lima; Renata Gorjão; Elaine Hatanaka; Maria Fernanda Cury-Boaventura; Erica Paula Portioli Silva; Joaquim Procopio; Rui Curi Fatty acids (FAs) have been shown to alter leucocyte function and thus to modulate inflammatory and immune responses. In this review, the effects of FAs...
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Clin Sci (Lond) (2007) 112 (1): 59–67.
Published: 01 December 2006
... of lymphocyte death were evaluated by flow cytometry. Plasma levels of glucose, NEFAs (non-esterified fatty acids) and ketone bodies (acetoacetate and β-hydroxybutyrate) were determined in rats fasted for 24 and 48 h. Lymphocytes obtained from fasted rats had an increase in DNA fragmentation...
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Clin Sci (Lond) (2006) 111 (5): 307–317.
Published: 13 October 2006
... mechanisms involved were examined by measuring mitochondrial depolarization, lipid accumulation and PPARγ (peroxisome-proliferator-activated receptor γ) activation. The results demonstrate that fatty acids induce apoptosis and necrosis of J774 cells. At high concentrations, fatty acids cause macrophage death...
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Clin Sci (Lond) (2005) 109 (2): 177–182.
Published: 25 July 2005
...Giovanna Priante; Estella Musacchio; Elisa Pagnin; Lorenzo A. Calò; Bruno Baggio A specific modulatory effect of PUFAs (polyunsaturated fatty acids) on gene expression of some cytokines involved in bone remodelling has been reported previously. In particular, although a direct action of AA...
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Clin Sci (Lond) (2003) 105 (1): 81–87.
Published: 01 July 2003
... endothelium fatty acid insulin meal Clinical Science (2003) 105, 81 87 (Printed in Great Britain) 81 The effect of a mixed meal on endothelium- dependent vasodilation is dependent on fat content in healthy humans Peter STEER*, Dennis M. SARABI*, Brita KARLSTRO¨M , Samar BASU , Christian BERNE*, Bengt...
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