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Keywords: fatty acid oxidation
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Articles

The importance of placental lipid metabolism across gestation in obese and non-obese pregnancies

In Collection
Reproductive Physiology and Disease
Kyle M. Siemers, Michelle L. Baack
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 31–34.
https://doi.org/10.1042/CS20220657
Published: 03 January 2023
... proteins fatty acid oxidation lipid metabolism obesity Placenta pregnancy The importance of studying placental lipid metabolism cannot be overemphasized because it not only influences pregnancy outcomes but also fetal growth, development, and life-long health [ 1 ]. A growing body of evidence...
View articletitled, The importance of placental lipid metabolism across gestation in obese and non-obese pregnancies
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Articles

Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats

William P. Martin, Meera Nair, Yeong H.D. Chuah, Daniel Malmodin, Anders Pedersen, Sanna Abrahamsson, Michaela Hutter, Mahmoud Abdelaal, Jessie A. Elliott, Naomi Fearon, Hans Eckhardt, Catherine Godson, Eoin P. Brennan, Lars Fändriks, Carel W. le Roux, Neil G. Docherty
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1485–1511.
https://doi.org/10.1042/CS20220205
Published: 03 November 2022
... kidney disease (DKD) by metabolic surgery is enhanced by pharmacotherapy promoting renal fatty acid oxidation (FAO). Using the Zucker Diabetic Fatty and Zucker Diabetic Sprague Dawley rat models of DKD, we conducted studies to determine if these effects could be replicated with a non-invasive bariatric...
View articletitled, Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats
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Includes: Supplementary data
Articles

Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer

Songtao Cheng, Gang Wang, Yejinpeng Wang, Liwei Cai, Kaiyu Qian, Lingao Ju, Xuefeng Liu, Yu Xiao, Xinghuan Wang
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (15): 1745–1758.
https://doi.org/10.1042/CS20190587
Published: 07 August 2019
... increased in BCa compared with paracancerous tissues. Inhibition of fatty acid oxidation (FAO) with etomoxir caused lipid accumulation, decreased adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide phosphate (NADPH) levels, suppressed BCa cell growth in vitro and in vivo , and reduced...
View articletitled, Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer
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Includes: Supplementary data
Articles

Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

Christina M. van der Beek, Emanuel E. Canfora, Kaatje Lenaerts, Freddy J. Troost, Steven W.M. Olde Damink, Jens J. Holst, Ad A.M. Masclee, Cornelis H.C. Dejong, Ellen E. Blaak
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (22): 2073–2082.
https://doi.org/10.1042/CS20160263
Published: 11 October 2016
..., NCT01826162. fatty acid oxidation intestinal hormones metabolic control obesity short-chain fatty acids Correspondence: Emanuel E. Canfora (email [email protected] ). 9 4 2016 10 6 2016 20 7 2016 20 7 2016 © 2016 The Author(s). published...
View articletitled, Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men
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Includes: Supplementary data
Articles

Alterations in plasma and tissue lipids associated with obesity and metabolic syndrome

Concepción M. Aguilera, Mercedes Gil-Campos, Ramón Cañete, Ángel Gil
Journal: Clinical Science
Clin Sci (Lond) (2008) 114 (3): 183–193.
https://doi.org/10.1042/CS20070115
Published: 08 January 2008
... oxidation. Lipid metabolism alterations in liver and peripheral tissues are addressed, with particular reference to adipose and muscle tissues, and the mechanisms by which some adipokines, namely leptin and adiponectin, mediate the regulation of fatty acid oxidation in those tissues. Activation of the AMPK...
View articletitled, Alterations in plasma and tissue lipids associated with obesity and metabolic syndrome
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Articles

Free and total carnitine and acylcarnitine content of plasma, urine, liver and muscle of alcoholics

C. De Sousa, N. W. Y. Leung, R. A. Chalmers, T. J. Peters
Journal: Clinical Science
Clin Sci (Lond) (1988) 75 (4): 437–440.
https://doi.org/10.1042/cs0750437
Published: 01 October 1988
... 1970 alcoholic myopathy carnitine fatty acid oxidation fatty liver Clinical Science (1988) 75,437-440 437 Free and total carnitine and acylcarnitine content of plasma, urine, liver and muscle of alcoholics C . DE SOUSA, N. W. Y. LEUNG, R. A. CHALMERS AND T. J. PETERS Section of F'erinatal...
View articletitled, Free and total carnitine and acylcarnitine content of plasma, urine, liver and muscle of alcoholics
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Articles

Palmitic acid oxidation and incorporation into triglyceride by needle liver biopsy specimens from control subjects and patients with alcoholic fatty liver disease

N. W. Y. Leung, T. J. Peters
Journal: Clinical Science
Clin Sci (Lond) (1986) 71 (3): 253–260.
https://doi.org/10.1042/cs0710253
Published: 01 September 1986
...N. W. Y. Leung; T. J. Peters 1. A micro-technique was developed to measure fatty acid oxidation in vitro and to investigate its possible derangement in alcoholic fatty liver disease. 2. Percutaneous liver biopsy specimens were obtained from nine control subjects and 28 alcoholic patients with mild...
View articletitled, Palmitic acid oxidation and incorporation into triglyceride by needle liver biopsy specimens from control subjects and patients with alcoholic fatty liver disease
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Articles

Fatty Acid Oxidation in Mitochondria from Needle Biopsy Samples of Human Skeletal Muscle

K. Gohil, D. A. Jones, R. H. T. Edwards
Journal: Clinical Science
Clin Sci (Lond) (1984) 66 (2): 173–178.
https://doi.org/10.1042/cs0660173
Published: 01 February 1984
... (a measure of β-oxidation) was very low. fatty acid oxidation mitochondria muscle needle biopsy 11 7 1983 8 8 1983 © 1984 The Biochemical Society and the Medical Research Society 1984 Clinical Science (1984) 66, 173-178 173 Fatty acid oxidation in mitochondria from needle biopsy...
View articletitled, Fatty Acid Oxidation in Mitochondria from Needle Biopsy Samples of Human Skeletal Muscle
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