.... Hepatic fatty acid synthesis rates measured in vivo with 3 H 2 O were significantly lower in the alcohol-fed animals than in controls. Activities of hepatic fatty acid synthase (EC 2.3.1.85) and acetyl-CoA carboxylase (EC 6.4.1.2) were reduced in the alcohol-fed rats. 3. These results indicate...

...Paulo R. L. de Vasconcelos; Michael G. W. Kettlewell; Geoffrey F. Gibbons; Dermot H. Williamson 1. Sepsis induced by caecal ligation and puncture increased the rates of hepatic cholesterogenesis and fatty acid synthesis in vivo compared with sham-operated rats. These changes were accompanied...

... and sterol synthesis in liver of alcohol-fed rats. 15 9 1987 1 10 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 cholesterol synthesis esterified and non-esterified cholesterol ethanol fatty acid synthesis fatty liver Clinical Science (1988) 74,407-412...

...S. Venkatesan; R. J. Ward; T. J. Peters 1. Liver slices from chronically alcohol-fed rats incubated with 3 H 2 O showed less than half the fatty acid synthesis rates of pair-fed controls. Addition of 50 mmol/l ethanol or of 10 mmol/l lactate and 1 mmol/l pyruvate to the incubation medium did...

... into fatty acid was measured and the absolute rate of fatty acid synthesis calculated. 2. Fatty acid synthesis rates were significantly lower in alcoholic fatty liver than in controls. 3. Fatty acid synthesis rates were similar in controls and patients with diabetic fatty livers. 4. Addition of 50 mmol/l...

... for the rates of fatty acid synthesis reported in the literature for intact tissues in vitro. 2. The distribution of label in fatty acids after incubations of adipose tissue with [1- 14 C]acetate was consistent with fatty acid synthesis de novo , not chain elongation. 3. The activities of citrate cleavage...