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1-23 of 23
Keywords: fatty liver
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Articles
Sebastian Bott, Justine Lallement, Alice Marino, Evangelos-Panagiotis Daskalopoulos, Christophe Beauloye, Hrag Esfahani, Chantal Dessy, Isabelle Anne Leclercq
Journal:
Clinical Science
Clin Sci (Lond) (2024) 138 (18): 1151–1171.
Published: 18 September 2024
... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adverse cardiac remodelling cardiac hypertrophy fatty liver foetal gene reprogramming MAFLD MASH Fonds De La Recherche Scientifique - FNRS (FNRS) 501100002661 P.C006.22...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (1): 17–30.
Published: 03 January 2023
...Shu-Huei Wang; Feng-Chiao Tsai; Heng-Huei Lin; Tse-Ya Yu; Chun-Heng Kuo; Hung-Yuan Li; Mao-Shin Lin Oxidative stress is vital for pathophysiology of atherosclerosis and non-alcoholic fatty liver disease (NAFLD). Monoamine oxidase (MAO) is an important source of oxidative stress in the vascular...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (13): 1019–1023.
Published: 01 July 2022
...Philip C. Calder Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease globally. The first stage of NAFLD is steatosis, the accumulation of triacylglycerols within hepatocytes. Inflammation and oxidative stress both contribute to progression to more severe disease. In 2004...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (12): 1281–1296.
Published: 26 June 2018
... Hernández-Muñoz ( [email protected] ) β-oxidation Fatty liver Gastritis Lipogenesis NAD/NADH redox state It is well documented that ethanol ingestion produces marked alterations in hepatic and extrahepatic tissues. High ethanol concentrations are capable of damaging the gastric...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (1): 53–63.
Published: 07 September 2012
...Adriana L. Burgueño; Tomas F. Gianotti; Noelia G. Mansilla; Carlos J. Pirola; Silvia Sookoian CVD (cardiovascular disease) is associated with abnormal liver enzymes, and NAFLD (non-alcoholic fatty liver disease) is independently associated with cardiovascular risk. To gain insights...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (6): 397–400.
Published: 14 December 2009
...Christopher D. Byrne NAFLD (non-alcoholic fatty liver disease) represents a spectrum of fatty liver diseases associated with an increased risk of Type 2 diabetes and cardiovascular disease. The spectrum of fatty liver diseases comprises simple steatosis, steatosis with inflammation [i.e. NASH (non...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (6): 401–410.
Published: 14 December 2009
...-alcoholic fatty liver disease) activity score] (8.3±2.4 compared with 2.3±10.7 in controls; P <0.01), serum AST, triacylglycerols and glucose were higher. Insulin sensitivity decreased in mice exposed to hypoxia relative to controls. The expression of the lipogenic genes SREBP-1c (sterol-regulatory...
Articles
Konstantinos Kantartzis, Fausto Machicao, Jürgen Machann, Fritz Schick, Andreas Fritsche, Hans-Ulrich Häring, Norbert Stefan
Journal:
Clinical Science
Clin Sci (Lond) (2009) 116 (6): 531–537.
Published: 12 February 2009
...-fat diet develop fatty liver, but not insulin resistance, suggesting that DGAT2 induces a dissociation between fatty liver and insulin resistance. In the present study, we investigated whether such a phenotype also exists in humans. For this purpose, we determined the relationships between genetic...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (8): 543–545.
Published: 13 March 2008
... of the common human disorder of non-alcoholic fatty liver disease. The accumulation of IHLs observed with prolonged fasting may also explain exacerbations of steatohepatitis seen sometimes with rapid weight loss, anorexia nervosa and parenteral nutrition. The findings also suggest caution against promoting...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (8): 547–552.
Published: 13 March 2008
... to the declaration of Helsinki (2000) of the World Medical Association. fasting fatty liver 3-hydroxybutyrate lipid 1 H-magnetic resonance spectroscopy non-alcoholic fatty liver disease (NAFLD) NAFLD (non-alcoholic fatty liver disease) is prevalent in obese subjects and is considered, by many...
Articles
Piero Portincasa, Ignazio Grattagliano, Bernhard H. Lauterburg, Vincenzo O. Palmieri, Giuseppe Palasciano, Frans Stellaard
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (2): 135–143.
Published: 13 July 2006
...Piero Portincasa; Ignazio Grattagliano; Bernhard H. Lauterburg; Vincenzo O. Palmieri; Giuseppe Palasciano; Frans Stellaard Effectively assessing subtle hepatic metabolic functions by novel non-invasive tests might be of clinical utility in scoring NAFLD (non-alcoholic fatty liver disease...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 90 (4): 307–313.
Published: 01 April 1996
...S. Eaton; A. M. Zaitoun; C. O. Record; K. Bartlett 1. The CoA and carnitine ester intermediates of mitochondrial β-oxidation have not previously been quantified in liver disease, although there is some evidence that β-oxidation is inhibited in alcoholic fatty liver. Mitochondria were isolated from...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1994) 87 (4): 441–446.
Published: 01 October 1994
... that enhanced hepatic fatty acid synthesis does not occur in rats fed alcohol and a low-fat diet for 4 weeks, and is thus not implicated in the pathogenesis of alcohol-induced fatty liver. 16 6 1993 12 5 1994 3 6 1994 © 1994 The Biochemical Society and the Medical Research Society 1994...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (4): 437–440.
Published: 01 October 1988
...C. De Sousa; N. W. Y. Leung; R. A. Chalmers; T. J. Peters 1. Plasma and urine free and total carnitine and acylcarnitine levels were assayed in 12 control subjects and 20 chronic alcoholics with fatty liver. Although the alcoholics had a wider range of values than the controls...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 74 (4): 407–412.
Published: 01 April 1988
... and sterol synthesis in liver of alcohol-fed rats. 15 9 1987 1 10 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 cholesterol synthesis esterified and non-esterified cholesterol ethanol fatty acid synthesis fatty liver Clinical Science (1988) 74,407-412...
Articles
Fatty acid synthesis and triacylglycerol accumulation in rat liver after chronic ethanol consumption
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (2): 159–163.
Published: 01 August 1987
... fatty acid synthesis. The reduced fatty acid synthesis observed is a consequence of triacylglycerol accumulation. 19 1 1987 16 2 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 ethanol fatty acid synthase fatty acid synthesis fatty liver lipogenesis...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (3): 253–260.
Published: 01 September 1986
...N. W. Y. Leung; T. J. Peters 1. A micro-technique was developed to measure fatty acid oxidation in vitro and to investigate its possible derangement in alcoholic fatty liver disease. 2. Percutaneous liver biopsy specimens were obtained from nine control subjects and 28 alcoholic patients with mild...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 69 (5): 517–523.
Published: 01 November 1985
... suggest that depressed lipolysis due to a relative deficiency of triglyceride lipase is not a causal factor in triglyceride accumulation in chronic alcoholic fatty liver. 17 4 1985 17 5 1985 © 1985 The Biochemical Society and the Medical Research Society 1985 alcoholic liver disease...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1984) 67 (3): 337–345.
Published: 01 September 1984
...S. R. Cairns; T. J. Peters 1. Needle biopsy specimens of liver were obtained from six control subjects with histologically normal liver and 11 chronic alcoholics with fatty liver. 2. Micro- and macro-lipid droplet fractions were isolated by differential flotation. These fractions, together...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 65 (6): 645–652.
Published: 01 December 1983
... was found in the patients with alcoholic liver disease whereas those of diabetic patients were similar to the controls. 3 5 1983 25 5 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 alcoholism cholesterol cirrhosis diabetes fatty acids fatty liver liver...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (2): 129–133.
Published: 01 August 1981
...D. N. Brindley © 1981 The Biochemical Society and the Medical Research Society 1981 atherosclerosis diabetes diet ethanol fatty liver fructose glucocorticoids insulin lipid metabolism lipoprotein lipase lipoproteins obesity l-α-phosphatidate phosphohydrolase sorbitol stress...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1975) 48 (5): 453–455.
Published: 01 May 1975
...C. R. Nair; O. P. Nirankari; P. N. Chhuttani; D. V. Datta 1. The mechanism of development of acute alcoholic fatty liver in the Rhesus monkey was investigated by studying the effect of Triton WR-1339 on plasma triglycerides. 2. After ethanol infusion, the rise in plasma triglyceride produced...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1973) 44 (5): 505–510.
Published: 01 May 1973
... accumulation of triglycerides in the ethanol-treated animals. 19 9 1972 © 1973 The Biochemical Society and the Medical Research Society 1973 ethanol fatty liver free fatty acids triglycerides β-receptor blocking agents Clinical Science (1973) 44, 505-510. ACUTE ALCOHOLIC FATTY LIVER...