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Keywords: fatty liver
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Articles
Clin Sci (Lond) (2018) 132 (12): 1281–1296.
Published: 26 June 2018
... ( Figure 2 ), closely correlating with the persistence of fatty liver promoted by the VE ( Figure 2 ). Therefore, it was evident that ethanol administration also affected the liver, but in a different manner from that exerted on the rat gastric mucosa. The rate for β- oxidation of FFA was first...
Articles
Clin Sci (Lond) (2013) 124 (1): 53–63.
Published: 07 September 2012
...Adriana L. Burgueño; Tomas F. Gianotti; Noelia G. Mansilla; Carlos J. Pirola; Silvia Sookoian CVD (cardiovascular disease) is associated with abnormal liver enzymes, and NAFLD (non-alcoholic fatty liver disease) is independently associated with cardiovascular risk. To gain insights into the...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2010) 118 (6): 397–400.
Published: 14 December 2009
...Christopher D. Byrne NAFLD (non-alcoholic fatty liver disease) represents a spectrum of fatty liver diseases associated with an increased risk of Type 2 diabetes and cardiovascular disease. The spectrum of fatty liver diseases comprises simple steatosis, steatosis with inflammation [i.e. NASH (non...
Articles
Clin Sci (Lond) (2010) 118 (6): 401–410.
Published: 14 December 2009
...-alcoholic fatty liver disease) activity score] (8.3±2.4 compared with 2.3±10.7 in controls; P <0.01), serum AST, triacylglycerols and glucose were higher. Insulin sensitivity decreased in mice exposed to hypoxia relative to controls. The expression of the lipogenic genes SREBP-1c (sterol-regulatory...
Articles
Clin Sci (Lond) (2009) 116 (6): 531–537.
Published: 12 February 2009
...-fat diet develop fatty liver, but not insulin resistance, suggesting that DGAT2 induces a dissociation between fatty liver and insulin resistance. In the present study, we investigated whether such a phenotype also exists in humans. For this purpose, we determined the relationships between genetic...
Articles
Clin Sci (Lond) (2008) 114 (8): 543–545.
Published: 13 March 2008
... pathogenesis of the common human disorder of non-alcoholic fatty liver disease. The accumulation of IHLs observed with prolonged fasting may also explain exacerbations of steatohepatitis seen sometimes with rapid weight loss, anorexia nervosa and parenteral nutrition. The findings also suggest caution against...
Articles
Clin Sci (Lond) (2008) 114 (8): 547–552.
Published: 13 March 2008
.... Correspondence: Dr Louise Moller (email louisem@dadlnet.dk ). 27 6 2007 26 10 2007 9 11 2007 9 11 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 fasting fatty liver 3-hydroxybutyrate lipid 1 H-magnetic resonance spectroscopy non-alcoholic fatty...
Articles
Clin Sci (Lond) (2006) 111 (2): 135–143.
Published: 13 July 2006
...Piero Portincasa; Ignazio Grattagliano; Bernhard H. Lauterburg; Vincenzo O. Palmieri; Giuseppe Palasciano; Frans Stellaard Effectively assessing subtle hepatic metabolic functions by novel non-invasive tests might be of clinical utility in scoring NAFLD (non-alcoholic fatty liver disease) and in...
Articles
Clin Sci (Lond) (1996) 90 (4): 307–313.
Published: 01 April 1996
...S. Eaton; A. M. Zaitoun; C. O. Record; K. Bartlett 1. The CoA and carnitine ester intermediates of mitochondrial β-oxidation have not previously been quantified in liver disease, although there is some evidence that β-oxidation is inhibited in alcoholic fatty liver. Mitochondria were isolated from...
Articles
Clin Sci (Lond) (1994) 87 (4): 441–446.
Published: 01 October 1994
... enhanced hepatic fatty acid synthesis does not occur in rats fed alcohol and a low-fat diet for 4 weeks, and is thus not implicated in the pathogenesis of alcohol-induced fatty liver. 16 6 1993 12 5 1994 3 6 1994 © 1994 The Biochemical Society and the Medical Research Society 1994...
Articles
Clin Sci (Lond) (1988) 75 (4): 437–440.
Published: 01 October 1988
...C. De Sousa; N. W. Y. Leung; R. A. Chalmers; T. J. Peters 1. Plasma and urine free and total carnitine and acylcarnitine levels were assayed in 12 control subjects and 20 chronic alcoholics with fatty liver. Although the alcoholics had a wider range of values than the controls, there was no...
Articles
Clin Sci (Lond) (1988) 74 (4): 407–412.
Published: 01 April 1988
... sterol synthesis in liver of alcohol-fed rats. 15 9 1987 1 10 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 cholesterol synthesis esterified and non-esterified cholesterol ethanol fatty acid synthesis fatty liver Clinical Science (1988) 74,407-412...
Articles
Clin Sci (Lond) (1987) 73 (2): 159–163.
Published: 01 August 1987
... fatty acid synthesis. The reduced fatty acid synthesis observed is a consequence of triacylglycerol accumulation. 19 1 1987 16 2 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 ethanol fatty acid synthase fatty acid synthesis fatty liver lipogenesis...
Articles
Clin Sci (Lond) (1986) 71 (3): 253–260.
Published: 01 September 1986
...N. W. Y. Leung; T. J. Peters 1. A micro-technique was developed to measure fatty acid oxidation in vitro and to investigate its possible derangement in alcoholic fatty liver disease. 2. Percutaneous liver biopsy specimens were obtained from nine control subjects and 28 alcoholic patients with mild...
Articles
Clin Sci (Lond) (1985) 69 (5): 517–523.
Published: 01 November 1985
... suggest that depressed lipolysis due to a relative deficiency of triglyceride lipase is not a causal factor in triglyceride accumulation in chronic alcoholic fatty liver. 17 4 1985 17 5 1985 © 1985 The Biochemical Society and the Medical Research Society 1985 alcoholic liver disease...
Articles
Clin Sci (Lond) (1984) 67 (3): 337–345.
Published: 01 September 1984
...S. R. Cairns; T. J. Peters 1. Needle biopsy specimens of liver were obtained from six control subjects with histologically normal liver and 11 chronic alcoholics with fatty liver. 2. Micro- and macro-lipid droplet fractions were isolated by differential flotation. These fractions, together with the...
Articles
Clin Sci (Lond) (1983) 65 (6): 645–652.
Published: 01 December 1983
... was found in the patients with alcoholic liver disease whereas those of diabetic patients were similar to the controls. 3 5 1983 25 5 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 alcoholism cholesterol cirrhosis diabetes fatty acids fatty liver...
Articles
Clin Sci (Lond) (1981) 61 (2): 129–133.
Published: 01 August 1981
...D. N. Brindley © 1981 The Biochemical Society and the Medical Research Society 1981 atherosclerosis diabetes diet ethanol fatty liver fructose glucocorticoids insulin lipid metabolism lipoprotein lipase lipoproteins obesity l-α-phosphatidate phosphohydrolase sorbitol stress...
Articles
Clin Sci Mol Med (1975) 48 (5): 453–455.
Published: 01 May 1975
...C. R. Nair; O. P. Nirankari; P. N. Chhuttani; D. V. Datta 1. The mechanism of development of acute alcoholic fatty liver in the Rhesus monkey was investigated by studying the effect of Triton WR-1339 on plasma triglycerides. 2. After ethanol infusion, the rise in plasma triglyceride produced by...
Articles
Clin Sci Mol Med (1973) 44 (5): 505–510.
Published: 01 May 1973
... accumulation of triglycerides in the ethanol-treated animals. © 1973 The Biochemical Society and the Medical Research Society 1973 ethanol fatty liver free fatty acids triglycerides β-receptor blocking agents 19 9 1972 Clinical Science (1973) 44, 505-510. ACUTE ALCOHOLIC FATTY LIVER IN...