... of incorporation, according to García-Sáinz and Fain [ 24 ]. 12 02 2018 14 05 2018 17 05 2018 17 05 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 β-oxidation Fatty liver Gastritis Lipogenesis NAD/NADH redox state...

...Adriana L. Burgueño; Tomas F. Gianotti; Noelia G. Mansilla; Carlos J. Pirola; Silvia Sookoian CVD (cardiovascular disease) is associated with abnormal liver enzymes, and NAFLD (non-alcoholic fatty liver disease) is independently associated with cardiovascular risk. To gain insights...

...Christopher D. Byrne NAFLD (non-alcoholic fatty liver disease) represents a spectrum of fatty liver diseases associated with an increased risk of Type 2 diabetes and cardiovascular disease. The spectrum of fatty liver diseases comprises simple steatosis, steatosis with inflammation [i.e. NASH (non...

...-alcoholic fatty liver disease) activity score] (8.3±2.4 compared with 2.3±10.7 in controls; P <0.01), serum AST, triacylglycerols and glucose were higher. Insulin sensitivity decreased in mice exposed to hypoxia relative to controls. The expression of the lipogenic genes SREBP-1c (sterol-regulatory...

...-fat diet develop fatty liver, but not insulin resistance, suggesting that DGAT2 induces a dissociation between fatty liver and insulin resistance. In the present study, we investigated whether such a phenotype also exists in humans. For this purpose, we determined the relationships between genetic...

... of the common human disorder of non-alcoholic fatty liver disease. The accumulation of IHLs observed with prolonged fasting may also explain exacerbations of steatohepatitis seen sometimes with rapid weight loss, anorexia nervosa and parenteral nutrition. The findings also suggest caution against promoting...

... Louise Moller (email louisem@dadlnet.dk ). 27 6 2007 26 10 2007 9 11 2007 9 11 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 fasting fatty liver 3-hydroxybutyrate lipid 1 H-magnetic resonance spectroscopy non-alcoholic fatty liver disease...

...Piero Portincasa; Ignazio Grattagliano; Bernhard H. Lauterburg; Vincenzo O. Palmieri; Giuseppe Palasciano; Frans Stellaard Effectively assessing subtle hepatic metabolic functions by novel non-invasive tests might be of clinical utility in scoring NAFLD (non-alcoholic fatty liver disease...

...S. Eaton; A. M. Zaitoun; C. O. Record; K. Bartlett 1. The CoA and carnitine ester intermediates of mitochondrial β-oxidation have not previously been quantified in liver disease, although there is some evidence that β-oxidation is inhibited in alcoholic fatty liver. Mitochondria were isolated from...

... that enhanced hepatic fatty acid synthesis does not occur in rats fed alcohol and a low-fat diet for 4 weeks, and is thus not implicated in the pathogenesis of alcohol-induced fatty liver. © 1994 The Biochemical Society and the Medical Research Society 1994 acetyl-CoA carboxylase ethanol fatty liver...

...C. De Sousa; N. W. Y. Leung; R. A. Chalmers; T. J. Peters 1. Plasma and urine free and total carnitine and acylcarnitine levels were assayed in 12 control subjects and 20 chronic alcoholics with fatty liver. Although the alcoholics had a wider range of values than the controls...

... and sterol synthesis in liver of alcohol-fed rats. 15 9 1987 1 10 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 cholesterol synthesis esterified and non-esterified cholesterol ethanol fatty acid synthesis fatty liver Clinical Science (1988) 74,407-412...

... fatty acid synthesis. The reduced fatty acid synthesis observed is a consequence of triacylglycerol accumulation. 19 1 1987 16 2 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 ethanol fatty acid synthase fatty acid synthesis fatty liver lipogenesis...

...N. W. Y. Leung; T. J. Peters 1. A micro-technique was developed to measure fatty acid oxidation in vitro and to investigate its possible derangement in alcoholic fatty liver disease. 2. Percutaneous liver biopsy specimens were obtained from nine control subjects and 28 alcoholic patients with mild...

... suggest that depressed lipolysis due to a relative deficiency of triglyceride lipase is not a causal factor in triglyceride accumulation in chronic alcoholic fatty liver. 17 4 1985 17 5 1985 © 1985 The Biochemical Society and the Medical Research Society 1985 alcoholic liver disease...

...S. R. Cairns; T. J. Peters 1. Needle biopsy specimens of liver were obtained from six control subjects with histologically normal liver and 11 chronic alcoholics with fatty liver. 2. Micro- and macro-lipid droplet fractions were isolated by differential flotation. These fractions, together...

... was found in the patients with alcoholic liver disease whereas those of diabetic patients were similar to the controls. 3 5 1983 25 5 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 alcoholism cholesterol cirrhosis diabetes fatty acids fatty liver liver...

...D. N. Brindley © 1981 The Biochemical Society and the Medical Research Society 1981 atherosclerosis diabetes diet ethanol fatty liver fructose glucocorticoids insulin lipid metabolism lipoprotein lipase lipoproteins obesity l-α-phosphatidate phosphohydrolase sorbitol stress...

...C. R. Nair; O. P. Nirankari; P. N. Chhuttani; D. V. Datta 1. The mechanism of development of acute alcoholic fatty liver in the Rhesus monkey was investigated by studying the effect of Triton WR-1339 on plasma triglycerides. 2. After ethanol infusion, the rise in plasma triglyceride produced...

... accumulation of triglycerides in the ethanol-treated animals. 19 9 1972 © 1973 The Biochemical Society and the Medical Research Society 1973 ethanol fatty liver free fatty acids triglycerides β-receptor blocking agents Clinical Science (1973) 44, 505-510. ACUTE ALCOHOLIC FATTY LIVER...