...Wenxue Huang; Yalin Zhan; Yunfei Zheng; Ye Han; Wenjie Hu; Jianxia Hou Objective: Ferritin, an iron-binding protein, is ubiquitous and highly conserved; it plays a crucial role in inflammation, which is the main symptom of periodontitis. Full-length cDNA library analyses have demonstrated abundant...

... of chemotherapy, mean NPBI rose significantly to 10.6±6.6 µmol/l (range, 0.6–21.3 µmol/l) in 18 (64.3%) of the 28 patients measured. The rise in NPBI was accompanied by a significant rise in total plasma iron and ferritin and a marked decrease in the latent iron-binding capacity. Concomitantly, plasma vitamins C...

... and the Medical Research Society © 2001 2001 ARDS ferritin haem oxygenase iron-regulatory proteins iron signalling reactive oxygen species sepsis transferrin 169Clinical Science (2001) 100, 169 182 (Printed in Great Britain) + R E V I E W Iron signalling regulated directly and through oxygen...

...Nan-Haw Chow; Chih-Jen Chang; Pi-Er Cheng; Tzong-Shin Tzai; Chun-Mei Huang; Johnny Shinn-Nan Lin 1. The serum ferritin level provides a valuable index of the body iron store. An increase in serum ferritin has often been observed in patients with neoplastic disease and correlates well with the stage...

...K. Pattanapanyasat; T. G. Hoy; A. Jacobs 1. Measurements of T-lymphocyte surface ferritin using flow cytometry show that phytohaemagglutinin (PHA) stimulation causes a marked increase in the number of cells bearing spleen-type (S) and heart-type (H) ferritin on their membrane, whereas...

...M. Wagstaff; M. Worwood; A. Jacobs 1. The ferritin content of iron-overloaded tissues was higher than that of normal tissues. There was also an increased iron content of ferritin extracted from these tissues. 2. In the limited number of tissues that we examined haemosiderin deposition appeared...

...G. Birgegård 1. Serum samples were collected from ten patients hospitalized for acute infections and from a control group of seven normal subjects. Tissue ferritin was obtained by purification of ferritin from normal human liver and from the ferritin standard of a commercially available assay kit...

... mmol. 4. Since the previously determined mean initial plasma ferritin concentration was 185 μg/l (462 pmol/l), there was 0·179–0·197 mmol of stored iron per 1 μg of plasma ferritin/l. 5. The study suggests that the assumption on which currently accepted values for daily body iron loss were calculated...

...M. Worwood; S. J. Cragg; M. Wagstaff; A. Jacobs 1. A high proportion of the ferritin in normal serum binds to concanavalin A. Binding is prevented by the addition of α-d-methylglucoside to the reaction mixture. 2. Ferritin in extracts of normal heart, liver and spleen or serum ferritin from...

...G. P. White; R. Bailey-Wood; A. Jacobs 1. The effect of iron chelators on iron uptake, ferritin and total protein synthesis was studied in cultured Chang cells. Desferrioxamine depressed ferritin synthesis and completely inhibited iron uptake by ferritin protein. Rhodotorulic acid reduced iron...

...M. Worwood; W. Aherne; S. Dawkins; A. Jacobs 1. The properties of ferritin in serum have been compared with those of ferritin from a number of tissues including blood cells. On anion-exchange chromatography with DEAE-Sephadex, the behaviour of human heart ferritin is different from that of liver...