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Keywords: fetal development
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Articles

Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta

Amy Catherine Kelly, Anita Kramer, Fredrick J. Rosario, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (23): 3123–3136.
https://doi.org/10.1042/CS20201050
Published: 07 December 2020
... fetal development Fetal programming neurodevelopmental disorders pregnancy serotonin (5-HT) trophoblast It is well established that a suboptimal intrauterine environment results in fetal adaptations with adverse consequences persisting after birth, throughout the lifespan and in future...
View article titled, Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta
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Includes: Supplementary data
Articles

Placental function in maternal obesity

Amy C. Kelly, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (8): 961–984.
https://doi.org/10.1042/CS20190266
Published: 21 April 2020
... to the next generation. Correspondence: Amy C. Kelly ( [email protected] ) 18 12 2019 07 04 2020 08 04 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 fetal development fetal growth human maternal-fetal...
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Articles

Placental DNA methylation of peroxisome-proliferator-activated receptor-γ co-activator-1α promoter is associated with maternal gestational glucose level

Xuemei Xie, Hongjie Gao, Wanjiang Zeng, Suhua Chen, Ling Feng, Dongrui Deng, Fu-yuan Qiao, Lihong Liao, Kenneth McCormick, Qin Ning, Xiaoping Luo
Journal: Clinical Science
Clin Sci (Lond) (2015) 129 (4): 385–394.
https://doi.org/10.1042/CS20140688
Published: 27 May 2015
.... The correlation between gestational 2-h post-OGTT glycaemia and CpG site-specific methylation in placenta was stronger in the gestational diabetes group. diabetes DNA methylation epigenetics fetal development maternal gestational glycaemia PPARGC1A • Intrauterine exposure to hyperglycaemia...
View article titled, Placental DNA methylation of peroxisome-proliferator-activated receptor-γ co-activator-1α promoter is associated with maternal gestational glucose level
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Includes: Supplementary data
Articles

Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches

Thomas Jansson, Theresa L. Powell
Journal: Clinical Science
Clin Sci (Lond) (2007) 113 (1): 1–13.
https://doi.org/10.1042/CS20060339
Published: 01 June 2007
... Thomas Jansson (email [email protected] ). 30 11 2006 2 2 2007 26 2 2007 © 2007 The Biochemical Society 2007 fetal development fetal growth maternal–fetal exchange nutrition pregnancy placental transport programming Genes and adult lifestyle factors have...
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