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1-13 of 13
Keywords: fetal programming
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (19): 2307–2327.
Published: 13 October 2021
... in the regulation of vitamin D metabolism [ 78 ] providing support for the importance of DNA methylation as a mediator of placental dysfunction in PE. Epigentics Fetal Programming IUGR Placenta Preeclampsia Preeclampsia (PE), the leading cause of maternal and fetal morbidity and mortality...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (23): 3123–3136.
Published: 07 December 2020
... of trophoblast serotonin synthesis and OGT protein expression. fetal development Fetal programming neurodevelopmental disorders pregnancy serotonin (5-HT) trophoblast All results were analyzed and plotted using PRISM (v9.0, GraphPad Software Inc, La Jolla, CA). The impact of fetal sex...
Includes: Supplementary data
Articles
Andrew M. South, Hossam A. Shaltout, Lisa K. Washburn, Alexa S. Hendricks, Debra I. Diz, Mark C. Chappell
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (1): 55–74.
Published: 08 January 2019
... an unknown etiology, considerable research efforts in both experimental models and human cohorts has focused on the premise that alterations in the fetal and perinatal environment are key factors in the development of hypertension in children and adults. The exact mechanisms of how fetal programming events...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (17): 1953–1962.
Published: 14 September 2018
... with chronic cardiovascular consequences. In a sheep model of fetal programming, in utero BM-exposed (BMX) offspring as adults exhibit elevated mean arterial pressure (MAP), decreased baroreflex sensitivity (BRS) for the control of heart rate and insulin resistance accompanied by dysregulation of the brain...
Articles
Jeanie B. Tryggestad, Anu Vishwanath, Shaoning Jiang, Ashwini Mallappa, April M. Teague, Yusuke Takahashi, David M. Thompson, Steven D. Chernausek
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (21): 1955–1967.
Published: 22 September 2016
... results in changes in miRNA expression. These changes affect target proteins known to function in energy homoeostasis and may predispose the children to future metabolic disease. fetal programming gestational diabetes human umbilical vein endothelial cell (HUVEC) miRNA • The chance...
Articles
Daniela F. Pinheiro, Patricia F. F. Pinheiro, José Buratini, JR, Anthony C. S. Castilho, Paula F. Lima, Luiza A. Trinca, Maria de Lourdes M. Vicentini-Paulino
Journal:
Clinical Science
Clin Sci (Lond) (2013) 125 (6): 281–289.
Published: 22 May 2013
... as fetal programming. The present study evaluated mRNA abundance and immunolocalization of nutrient transporters as well as enterocytes proliferation in the proximal, median and distal segments of small intestine of rats born to protein-restricted dams. Pregnant rats were fed hypoproteic (6% protein...
Articles
Heather L. Blackmore, Ana V. Piekarz, Denise S. Fernandez-Twinn, John R. Mercer, Nichola Figg, Martin Bennett, Susan E. Ozanne
Journal:
Clinical Science
Clin Sci (Lond) (2012) 123 (4): 251–257.
Published: 30 April 2012
... Commons Attribution Non-Commercial Licence ( http://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. apolipoprotein atherosclerosis cholesterol fetal programming low...
Articles
Maternal antioxidant blocks programmed cardiovascular and behavioural stress responses in adult mice
Robert D. Roghair, John A. Wemmie, Kenneth A. Volk, Thomas D. Scholz, Fred S. Lamb, Jeffrey L. Segar
Journal:
Clinical Science
Clin Sci (Lond) (2011) 121 (10): 427–436.
Published: 25 July 2011
...). To further explore the relative importance of prenatal CBX and postnatal high-fat diet in the establishment of aortic superoxide production, additional mice were evaluated while receiving either the standard or high-fat diets. antioxidant cardiovascular response carbenoxolone fetal programming...
Articles
Emily M. Segar, Andrew W. Norris, Jian-Rong Yao, Shanming Hu, Stacia L. Koppenhafer, Robert D. Roghair, Jeffrey L. Segar, Thomas D. Scholz
Journal:
Clinical Science
Clin Sci (Lond) (2009) 117 (3): 129–138.
Published: 02 July 2009
... SNP sodium nitroprusside STZ streptozotocin cardiovascular disease fetal programming endothelium gestational diabetes glucose vascular smooth muscle References 1 Curhan G. C. Willett W. C. Rimm E. B. Spiegelman D. Ascherio A. L. Stampfer M. J...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2009) 117 (2): 75–84.
Published: 15 June 2009
.... Correspondence: Dr Nick Ashton (email [email protected] ). 11 7 2008 19 12 2008 7 1 2009 7 1 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 fetal programming kidney Na + /K + /2Cl − co-transporter (NKCC2) pressure–natriuresis relationship...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 113 (5): 219–232.
Published: 01 August 2007
... to the concept of ‘fetal programming’. The molecular mechanisms that underlie this relationship remain unclear, but are being extensively investigated using a number of experimental models. One major hypothesis for early life physiological programming implicates fetal overexposure to stress (glucocorticoid...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (1): 1–11.
Published: 23 June 2005
... The Biochemical Society 2005 appetite cardiovascular disease diabetes fetal programming metabolic syndrome obesity perinatal programming Obesity is a key risk factor in the development of Type II diabetes, high blood pressure, cardiovascular disease and cancers such as breast cancer [ 1...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (5): 607–615.
Published: 01 November 1996
... independently or in concert. 1 7 1996 19 7 1996 © 1996 The Biochemical Society and the Medical Research Society 1996 fetal programming glucocorticoids hypertension kidney maternal nutrition rats Clinical Science (1996) 91,607-615 (Printed in Great Britain) 607 Weanling rats...