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Keywords: fetal programming
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Clin Sci (Lond) (2021) 135 (19): 2307–2327.
Published: 13 October 2021
... the epigenetic mechanisms that contribute to normal placental development and the initiating events in PE may lead to novel therapeutic targets in PE that improve fetal growth and mitigate increased CV risk in the offspring. Epigentics Fetal Programming IUGR Placenta Preeclampsia Preeclampsia (PE...
Clin Sci (Lond) (2018) 132 (17): 1953–1962.
Published: 14 September 2018
... with chronic cardiovascular consequences. In a sheep model of fetal programming, in utero BM-exposed (BMX) offspring as adults exhibit elevated mean arterial pressure (MAP), decreased baroreflex sensitivity (BRS) for the control of heart rate and insulin resistance accompanied by dysregulation of the brain...
Clin Sci (Lond) (2016) 130 (21): 1955–1967.
Published: 22 September 2016
... on a separate chip. fetal programming gestational diabetes human umbilical vein endothelial cell (HUVEC) miRNA • The chance of a child developing diabetes is much higher if the child is born to a mother with diabetes during pregnancy and is related, in part, to fetal exposure to a diabetic...
Clin Sci (Lond) (2012) 123 (4): 251–257.
Published: 30 April 2012
.... apolipoprotein atherosclerosis cholesterol fetal programming low-protein diet maternal nutrition offspring Specific primary antibodies were used for the following: α-SMA (α-smooth muscle actin) (DAKO M0851, 1:500 dilution), Mac3 (macrophage marker 3) (M3/84; Pharmingen, 1:200 dilution), p-ATM...
Clin Sci (Lond) (2011) 121 (10): 427–436.
Published: 25 July 2011
... cardiovascular response carbenoxolone fetal programming 11β-hydroxysteroid dehydrogenase stress In addition to the programming of stress-induced hypertension, excessive fetal glucocorticoid exposure may increase the risk of developing anxiety disorders, including PTSD (post-traumatic stress disorder...
Clin Sci (Lond) (2009) 117 (2): 75–84.
Published: 15 June 2009
... Nick Ashton (email nick.ashton@manchester.ac.uk ). 11 7 2008 19 12 2008 7 1 2009 7 1 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 fetal programming kidney Na + /K + /2Cl − co-transporter (NKCC2) pressure–natriuresis relationship sodium...
Clin Sci (Lond) (2007) 113 (5): 219–232.
Published: 01 August 2007
... to the concept of ‘fetal programming’. The molecular mechanisms that underlie this relationship remain unclear, but are being extensively investigated using a number of experimental models. One major hypothesis for early life physiological programming implicates fetal overexposure to stress (glucocorticoid...
Clin Sci (Lond) (2005) 109 (1): 1–11.
Published: 23 June 2005
... of these and future studies could prove clinically crucial, particularly in the debate over the benefits of breast feeding, which provides a lower plane of nutrition compared with formula feeding. The Biochemical Society 2005 appetite cardiovascular disease diabetes fetal programming metabolic syndrome...