... protein fibrinogen and the negative acute-phase protein albumin. Synthesis rates of muscle protein, fibrinogen and albumin were measured simultaneously before and 4 h after the end of surgery from the incorporation of L -[ 2 H 5 ]phenylalanine (given at 43 mg/kg of body weight) in 12 patients undergoing...

... male volunteers who received 10 ml/kg of body weight of these colloids as intravenous infusions over 30 min. Venous blood was sampled and urine was collected over 8 h to outline the volume expansion and blood–interstitial fluid space transport of three plasma proteins (albumin, fibrinogen...

... between C3 and some cardiovascular risk factors when jointly analysed with CRP (C-reactive protein) and fibrinogen. In a cohort of 756 unselected adults, 39% of whom had the metabolic syndrome, C3 and other risk variables were evaluated in a cross-sectional manner. In a logistic regression model...

.... An n -3 fatty-acid-enriched nutritional supplement will moderate aspects of cachexia in cancer patients. The present study examined the effect of such a supplement on hepatic synthesis of albumin and fibrinogen. Albumin and fibrinogen synthesis were measured in the fed and fasting state in eight weight...

...)], platelet activation (soluble P-selectin) and coagulation (fibrinogen) and their inter-relationships in stable outpatients with CHF in sinus rhythm. We recruited 46 patients [23 male; age 64±13 years (mean±S.D.); range 38–85 years] with CHF. Baseline levels of serum LHP ( P <0.002), plasma vWf ( P...

...-to-moderate essential hypertension. Fibrinogen, thrombin–antithrombin complex (TAT) and Factor VII were determined in plasma at rest and after a mental stress test following placebo for 6 weeks, or ramipril for 6 weeks or 6 months. Ramipril reduced resting TAT, and tended to reduce fibrinogen; Factor VII...

... women. 2. Women with proteinuric pre-eclampsia showed evidence of activated, degranulated platelets in the circulation, with increased platelet-bound fibrinogen, increased expression of the lysosomal granule membrane antigen, CD63, and raised plasma levels of β-thromboglobulin. 3. CD63 expression and β...

... volume, indicating a 14% or 438 ml decline in plasma volume; increased excretion of water, Na + and K + accounted for loss of only 179 ml of extracellular water. 3. Plasma cholesterol and fibrinogen concentrations rose in the elderly subjects from 4.9 mmol/l and 2.97 g/l (control) to 5.45 mmol/l and 3.39...

...R. D. Hughes; D. A. Lane; H. Ireland; P. G. Langley; A. E. S. Gimson; Roger Williams 1. The concentration in plasma of fibrinogen derivatives fibrinopeptide A (FPA) and Bβ1-42 and the platelet release products β-thromboglobulin (βTG) and platelet factor 4 (PF4) have been determined in patients...

.... The fibrinogen levels were higher in the diabetic group ( P < 0·05) and correlated with the low shear blood viscosity ( r s = 0·38, P < 0·05). 3. In a prospective study, 74 insulin-treated diabetic patients with background retinopathy were randomized into two groups. Thirty-six patients were on attempted...

...J. C. Ferguson; N. Mackay; J. A. D. Philip; D. J. Sumner 1. Simultaneous platelet and fibrinogen survival studies were carried out on a group of seven normal persons and eleven diabetic patients. 2. Survival time was calculated: (a) by measuring the interval between 50% of the maximum radioactivity...

... and the presence of heparin and/or fibrinogen in the suspending medium were necessary for dye reduction. 3. NBT complexed with and precipitated heparin and/or fibrinogen from solution. The percentage of cells reducing the dye and the degree of precipitation of fibrinogen and heparin depended on the concentration...

...E. N. Wardle 1. Intravascular coagulation has been assessed by following the catabolism of 131 I-fibrinogen in relation to 125 I-labelled antigen disposal during anaphylaxis and acute and chronic serum sickness glomerulonephritis in rabbits. 2. As a result of antigen challenge early in the bovine...

... of failure was associated with an increase in fibrinogen, fibrin degradation products and α 1 -antitrypsin, but not with any alteration of plasminogen activator, plasminogen, the serum inhibitor of plasminogen activation or α 2 -macroglobulin. 3. Compared with patients with heart disease, there were...