... in thrombosis and wound healing with a particular focus on: (i) the influence of plasma FXIIIa on the formation of stable fibrin clots able to withstand mechanical and enzymatic breakdown through fibrin–fibrin cross-linking and cross-linking of fibrinolysis inhibitors, in particular α 2 -antiplasmin; (ii...

...Roger E. Peverill; Helena J. Teede; Erica Malan; Dimitra Kotsopoulos; Joseph J. Smolich; Barry P. Mcgrath The contribution of obesity to the occurrence of cardiovascular events may not be wholly related to its influence on traditional risk factors. Coagulation and fibrinolysis may also influence...

... Laboratory facility. TNF-α (Knoll Pharmaceuticals), bradykinin (Clinalfa), acetylcholine (Novartis) and SNP (sodium nitroprusside; David Bull Laboratories) were administered following dissolution in 0.9% saline. coronary disease endothelial function fibrinolysis inflammation tumour necrosis...

...Stanley CHIA; Robert WILSON; Christopher A. LUDLAM; David J. WEBB; Andrew D. FLAPAN; David E. NEWBY Hyperhomocysteinaemia is a prothrombotic condition that may cause oxidative endothelial injury and impair endogenous fibrinolysis. Vitamin supplementation enhances endothelial function...

... profile for cardiovascular disease. This beneficial effect was not mirrored in vascular function or oxidative stress evaluation. INTRODUCTION Atherosclerosis remains the leading cause of morbidity and mortality in developed countries. Risk factors for Key words: diet, endothelial function, fibrinolysis...

... injection of endotoxin alone or in combination with blocking monoclonal antibodies directed against tumour necrosis factor or interleukin 6 or in combination with pentoxifylline. Furthermore, to assess the effect of coagulation activation on the activation of fibrinolysis, another group of chimpanzees...

... of cardiac output, a reduction in splanchnic flow might occur. These haemodynamic changes will not be of major importance for Factor VIII, which has a long elimination half-life. This is in contrast to the effect Key words: Idesamind-bvasopressin, duplex scanning, fibrinolysis, haemodynamics, lndocyanine...

... the two groups, except the plasminogen activator inhibitor type 1 antigen level, which remained significantly lower in the diabetic patients. The mean increments in each parameter did not differ between the two groups. 3. Coagulation and fibrinolysis were assessed in response to acute insulin-induced...

... not change in either group. 6. The results indicate that vasopressin regulates the intrinsic coagulation pathway and fibrinolytic system in the absence of adrenaline release. Key words: colonoscopy, Factor VIII, fibrinolysis, vaso- pressin. Correspondence: Dr P. J. Grant, University Department of Medicine...

...B. M. Fisher; J. D. Quin; A. Rumley; S. E. Lennie; M. Small; A. C. MacCuish; G. D. O. Lowe 1. The effects of acute hypoglycaemia on haemostasis, fibrinolysis, blood viscosity and erythrocyte aggregation were examined after acute insulin-induced hypoglycaemia in six normal male subjects and in six...

... 1986 © 1986 The Biochemical Society and the Medical Research Society 1986 adrenaline factor VIII fibrinolysis nausea vasopressin Clinical Science (1 986) 7 1, 621-624 SHORT COMMUNICATION 621 Vasopressin and catecholamine secretion during apomorphine- induced nausea mediate acute...

... in plasma activator activity and effects on FPA generation consistent with low-level activation of the coagulation mechanism. Endogenous vaso- pressin could mediate alterations in haemostatic function known t o accompany events such as surgical operations. P < 0.0001). Key words: factor VIII, fibrinolysis...

... and the Medical Research Society 1981 fibrinolysis kidney glomerulus thromboplastin Clinical Science (198 I) 60,47-53 47 Clearance of fibrin from glomeruli. Renal cortical fibrinolytic response after thromboplastin infusion in the rat A. SANCHEZ-IBARROLA, S. QAZZAZ AND P. NAISH Medical Research...

... in relation to mediation of progressive intrarenal vascular disease is discussed. 21 7 1978 23 10 1978 © 1979 The Biochemical Society and the Medical Research Society 1979 blood vessels fibrinolysis hypertension kidney platelets pregnancy Clinical Science (1979) 56,189-192...

... Research Society 1978 fibrinolysis peptides plasminogen activator vasopressins Clinical Science and Molecular Medicine (1978) S4,403-409 Structure-activity relations of the fibrinolytic response to vasopressins in man J. D. CASH, A. M. A. GADER, J. L. MULDER«1'* AND J. H. CORT<2' Regional Blood...

... in platelet function may be causally related to the intra-renal vascular abnormalities. 6. The possible role of oestrogens in causing these disturbances or unmasking pre-existing abnormalities of platelet function or fibrinolysis is discussed. 14 7 1976 18 8 1976 © 1977 The Biochemical...

... digests should be taken into account in the development of D dimer assays to monitor fibrin lysis in vivo. 8 1 1975 © 1975 The Biochemical Society and the Medical Research Society 1975 D dimer D-E complex fibrinolysis Clinical Science and Molecular Medicine (1 975) 49, 149-1 56...

... was decreased in patients with cardiac failure. 6 12 1972 © 1973 The Biochemical Society and the Medical Research Society 1973 fibrinolysis cardiac failure plasminogen plasminogen activator fibrinogen α 1 -antitrypsin α 2 -macroglobulin venous stasis Clinical Science and Molecular...