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Keywords: gender
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Clin Sci (Lond) (2020) 134 (23): 3159–3174.
Published: 09 December 2020
... the relationship between the inflammatory response, gender and gut microbiota, which may provide new strategies to prevent the symptoms and long-term sequelae of OA. The deparaffinized and rehydrated 5-μm sections were rinsed with PBS and blocked for 30 min in 0.1% H 2 O 2 to inhibit endogenous peroxidase...
Includes: Supplementary data
Clin Sci (Lond) (2020) 134 (16): 2203–2207.
Published: 26 August 2020
... as distinct. In this editorial, we provide an overview of mechanisms related to differences in vascular pathophysiology between men and women and explore the contributions of both sex and gender. Gender Ischaemic heart disease Sex Vascular biology Cardiovascular disease (CVD) is a leading cause...
Clin Sci (Lond) (2017) 131 (9): 803–822.
Published: 19 April 2017
...Renée Ventura-Clapier; Maryline Moulin; Jérôme Piquereau; Christophe Lemaire; Mathias Mericskay; Vladimir Veksler; Anne Garnier It is increasingly acknowledged that a sex and gender specificity affects the occurrence, development, and consequence of a plethora of pathologies. Mitochondria...
Clin Sci (Lond) (2017) 131 (6): 449–469.
Published: 06 March 2017
...Maria Buoncervello; Matteo Marconi; Alessandra Carè; Paola Piscopo; Walter Malorni; Paola Matarrese The biology of sex differences deals with the study of the disparities between females and males and the related biological mechanisms. Gender medicine focuses on the impact of gender and sex...
Includes: Supplementary data
Clin Sci (Lond) (2016) 130 (19): 1711–1725.
Published: 23 August 2016
...Rita Ostan; Daniela Monti; Paola Gueresi; Mauro Bussolotto; Claudio Franceschi; Giovannella Baggio Data showing a remarkable gender difference in life expectancy and mortality, including survival to extreme age, are reviewed starting from clinical and demographic data and stressing the importance...
Clin Sci (Lond) (2016) 130 (1): 1–7.
Published: 19 November 2015
...Marianne J. Legato This article is intended to illuminate several important changes in our concept of gender-specific medicine in the genomic era. It reviews the history of gender-specific medicine, pointing out the changes in our perception of the nature of biological sex and our expanding...
Clin Sci (Lond) (2015) 128 (8): 507–516.
Published: 23 January 2015
... with the notion that in humans changes in lung volume are detected by lung mechanoreceptors, whereas chest wall reflexes play no role in RSA. No difference in RSA emerged between genders during resting breathing or modest breath-hold hyperventilation. Table 1 Number and characteristics of the subjects...
Clin Sci (Lond) (2011) 120 (4): 153–160.
Published: 02 November 2010
..., there was no significant difference ( P =0.163). Although there were gender differences in vascular function and structure in the young adult population examined in this study, many of the differences were eliminated simply by adjusting for artery diameter. However, the lower EID observed in males could not be explained...
Clin Sci (Lond) (2010) 119 (12): 493–513.
Published: 01 September 2010
... and women, the clinical impact of sex hormones on CVD, and summarize our current understanding of the pathogenesis of atherosclerosis with a focus on gender differences in CVD, its clinical presentation and course, and pathobiology. The critical animal and human data that pertain to the role of oestrogens...
Clin Sci (Lond) (2009) 117 (10): 355–364.
Published: 07 September 2009
... Licence ( http://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. androgen cardiovascular system endothelial progenitor cell endothelium gender oestrogen stem cell...
Clin Sci (Lond) (2008) 115 (1): 35–42.
Published: 02 June 2008
... improved glucose tolerance in patients. Gender-related differences have also been observed in the clinical responsiveness to these drugs, but the mechanism behind this is unclear. In the present study, we have investigated whether these drugs and the fatty acid palmitate influence the pancreatic...
Clin Sci (Lond) (2008) 114 (4): 305–311.
Published: 15 January 2008
... transcriptase (TaqMan) PCR method, as reported previously [ 7 ]. To normalize our expression data, PBGD (porphobilinogen deaminase) was used as a housekeeping gene (GenBank® accession no. X06827), as reported previously [ 7 ]. albuminuria blood pressure gender kidney hypertension Munich Wistar Frömter...
Clin Sci (Lond) (2007) 112 (6): 363–373.
Published: 12 February 2007
... symptoms of acute infections at the physical examination ( n =14) were asked to return 2 weeks after recuperation to allow time for the levels of cytokines to normalize. gender cytokine inflammation self-rated health sickness behaviour subjective health Aging is accompanied by increased...
Clin Sci (Lond) (2007) 112 (6): 353–361.
Published: 12 February 2007
...Andrew J. Hogarth; Alan F. Mackintosh; David A. S. G. Mary The risk of cardiovascular disease has been linked to sympathetic activation and its incidence is known to be lower in women than in men. However, the effect of gender on the sympathetic vasoconstrictor drive has not yet been established...
Clin Sci (Lond) (2006) 111 (5): 333–340.
Published: 13 October 2006
... polymorphism) in 811 patients with CHD (of which 508 were patients with MI) and 905 normal controls in a Chinese population. The polymorphisms were in linkage disequilibrium ( r 2 =0.854–0.973). Analyses were conducted by gender, because the ACE2 gene is on the X chromosome. In females, an association...
Clin Sci (Lond) (2003) 104 (3): 267–273.
Published: 14 February 2003
... Scott G. Thomas, at Faculty of Physical Education and Health, 55 Harbord St, Toronto, Canada M5S 2W6 (e-mail scott.thomas@utoronto.ca ). 9 7 2002 25 10 2002 29 11 2002 The Biochemical Society and the Medical Research Society © 2003 2003 aging blood volume gender hormone...
Clin Sci (Lond) (2002) 103 (s2002): 158S–161S.
Published: 01 September 2002
...Nuria FERNÁNDEZ; Elena SANZ; Luis MONGE; María Angeles MARTÍNEZ; Godofredo DIÉGUEZ; Angel Luis GARCÍA-VILLALÓN The aim of this study was to analyse the modulatory role of endothelin-1 and vasopressin in sympathetic vasoconstriction, and whether there are gender differences in this modulatory role...
Clin Sci (Lond) (2002) 102 (2): 241–246.
Published: 10 January 2002
... and the ability of insulin to enhance endothelium-dependent vasodilatation. Correspondence: Dr Lars Lind (e-mail lars.lind@medsci.uu.se ). 10 1 2001 5 9 2001 12 10 2001 The Biochemical Society and the Medical Research Society © 2002 2002 blood flow endothelium gender glucose...
Clin Sci (Lond) (1998) 95 (4): 445–451.
Published: 01 October 1998
...Rachel OKUNIEWSKI; Elizabeth A. DAVIS; Bevyn JARROTT; Robert E. WIDDOP 1. The objective of this study was to determine the influence of gender on the development of renal hypertension in Sprague–Dawley rats using the Goldblatt two-kidney, one-clip (2K1C) model. In addition, this study examined...
Clin Sci (Lond) (1997) 93 (6): 513–518.
Published: 01 December 1997
... 1997 © 1997 The Biochemical Society and the Medical Research Society 1997 endothelium gender nitric oxide Clinical Science (1997) 93,s 13-5 18 (Printed in Great Britain) 513 Vasoconstrictor sensitivity to noradrenaline and NG-monomethyl-L-arginine in men and women Barry 1. KNEALE*t...
Clin Sci (Lond) (1997) 93 (4): 299–308.
Published: 01 October 1997
...Kuniaki Otsuka; Germaine Cornelissen; Franz Halberg 1. The fractal scaling of heart rate variability, gauged by the correlation dimension (CD), is hypothesized to be characterized by a time structure (chronome), which in health shows differences as a function of gender and age. 2. From 24 h Holter...
Clin Sci (Lond) (1997) 92 (4): 345–349.
Published: 01 April 1997
... a difference in gender-based development as noted in the separate context of fetal lung maturation. 21 11 1996 28 11 1996 © 1997 The Biochemical Society and the Medical Research Society 1997 complexity electrocardiogram fetus gender heart rate variability Clinical Science (1997...
Clin Sci (Lond) (1995) 89 (3): 219–225.
Published: 01 September 1995
..., mean skin-surface temperature, fingertip capillary blood flow and metabolic heat production were measured. Dose—response curves were plotted for all measured variables, and males and females were compared to identify potential gender differences. 3. Core temperature decreased with all doses...