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Keywords: genotype
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Articles
William J. Anderson, Philip M. Short, Peter A. Williamson, Ashley E. Morrison, Colin Palmer, Roger Tavendale, Brian J. Lipworth
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (1): 75–83.
Published: 09 September 2013
... be detrimental in asthma. The isomeric formulation of salbutamol and the B2ADR (β 2 adrenoceptor) 16 genotype may also influence this phenomenon. We performed a randomized, double-blind, placebo-controlled, triple crossover, proof of concept trial comparing 2 weeks of regular therapy with inhaled racemic...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (8): 517–519.
Published: 08 January 2013
... previously that the Arg 16 polymorphism may confer an increased risk of exacerbation following prolonged β 2 -adrenergic receptor agonist use. These results suggest Gly16Arg genotyping in Caucasian asthma patients may have a role in the clinical management of asthma by influencing the decision of which add...
Articles
Brian J. Lipworth, Kaninika Basu, Helen P. Donald, Roger Tavendale, Donald F. Macgregor, Simon A. Ogston, Colin N. A. Palmer, Somnath Mukhopadhyay
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (8): 521–528.
Published: 08 January 2013
...Brian J. Lipworth; Kaninika Basu; Helen P. Donald; Roger Tavendale; Donald F. Macgregor; Simon A. Ogston; Colin N. A. Palmer; Somnath Mukhopadhyay The Arg 16 β 2 receptor genotype confers increased susceptibility to exacerbations in asthmatic children taking regular LABA (long-acting β 2 agonists...