... endothelial cell glomerular filtration nephrotic syndrome podocyte proteinuria Normal human urine contains only very small quantities of albumin, less than 30 mg of albumin being excreted by healthy adults in 24 h. The appearance of large amounts of albumin in the urine is a cardinal sign...

... or enalapril, and from 45 to 135 min after losartan and placebo or losartan and enalapril. Renal function was studied using clearance of sodium, lithium, uric acid, inulin and para -aminohippuric acid. To examine further the determinants of glomerular filtration at the microcirculation level, fractional...

...Anders Edlund; Hans Ohlsén; Alf Sollevi 1. The effects of local intra-arterial infusion of adenosine on renal blood flow, glomerular filtration and renin release in eight healthy awake subjects have been examined. 2. Renal blood flow and glomerular filtration rate were measured as the clearances...

...N. V. Olsen; J. M. Hansen; S. D. Ladefoged; N. Fogh-Andersen; P. P. Leyssac 1. Using the renal clearance of lithium ( C Li ) as an index of proximal tubular outflow of sodium and water, together with simultaneous measurements of effective renal plasma flow, glomerular filtration rate (GFR...

...N. V. Olsen; J. M. Hansen; S. D. Ladefoged; N. Fogh-Andersen; S. Levin Nielsen; P. P. Leyssac 1. Amino acids have been used to test renal reserve filtration capacity. Previous studies suggest that amino acids increase glomerular filtration rate (GFR) by reducing distal tubular flow...

... reabsorption. Some other properties of human myeloma light chains may determine their renal handling and nephrotoxicity. Key words: glomerular filtration, isoelectric point, kidney, light chain, tubular reabsorption. Correspondence: Dr Christine Baylis, Department of Physi- ology, University of West Virginia...

...Bernardo Rodríguez-Iturbe; Josē Herrera; Rafael García 1. We studied the relationship between changes in glomerular filtration rate (GFR) determined as inulin clearance (C In ), and changes in renal blood flow (RBF), determined as p -aminohippurate clearance (C PAH ), after the ingestion of a large...

... blood flow and glomerular filtration rate responses to lowering renal perfusion pressure from 125 to 75 mmHg in the anaesthetized dog. To study the role of renal nerves in these responses, paired innervated and denervated kidneys were studied in each animal. 2. Hypoxia ( P o 2 43 ± 3 mmHg) affected...

... 7 9 1978 © 1979 The Biochemical Society and the Medical Research Society 1979 glomerular filtration haemodynamics renal arteriolar resistances salt hypertension spontaneous hypertension Clinical Science (1979) 56,203-209 Regulation of glomerular capillary pressure and filtration...

..., concentration- polarization, glomerular filtration, 1 kidney, proteinuria. Introduction The wide use of filters in industrial processes has focussed attention on the manner in which their behaviour in liquid-phase processes can be affected by concentration-polarization (Blatt, Dravid, Michaels & Nelsen, 1970...

... glomerular filtration rate was unchanged, whereas effective renal plasma flow increased, so that filtration fraction decreased significantly. A similar increase in urinary sodium occurred whether subjects received a low or high sodium diet. Indices which related to the distal delivery of filtrate (fractional...