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1-22 of 22
Keywords: glucose tolerance
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Articles
Anwar Khan, Sherouk Fouda, Ali Mahzari, Stanley M.H. Chan, Xiu Zhou, Cherubina Ratnam, Ross Vlahos, Ji-Ming Ye
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (13): 1659–1673.
Published: 01 July 2020
... to muscles to offset the supposed benefit of reduced body weight gain on insulin signalling in this major site for glucose tolerance (or insulin action). The study was conducted in mice exposed to chronic CS followed by either a chow (CH) diet or a high-fat (HF) diet. CS increased triglyceride (TG) levels...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (9): 589–590.
Published: 02 April 2008
... and co-workers report that infusion of glucagon raised fasting plasma glucose concentrations and impaired glucose tolerance over 4 weeks in mice, thus demonstrating a sustained glycaemic effect of hyperglucagonaemia. Nonetheless, compelling evidence that glucagon contributes to the pathogenesis...
Articles
Long-term hyperglucagonaemia induces early metabolic and renal phenotypes of Type 2 diabetes in mice
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (9): 591–601.
Published: 02 April 2008
...Xiao C. Li; Tang-dong Liao; Jia L. Zhuo Clinical studies have shown that patients with early Type 2 diabetes often have elevated serum glucagon rather than insulin deficiency. Imbalance of insulin and glucagon in favouring the latter may contribute to impaired glucose tolerance, persistent...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (12): 599–606.
Published: 14 May 2007
... diabetes, to test this hypothesis, we have investigated oxidative stress pathways and DNA damage in patients with IGR and newly diagnosed Type 2 diabetes. The study population consisted of 92 subjects with NGT (normal glucose tolerance), 78 patients with IGR and 113 patients with newly diagnosed diabetes...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (9): 493–498.
Published: 02 April 2007
... The Biochemical Society 2007 endothelium-derived dilation echocardiography glucose tolerance hyperglycaemia insulin overweight children A primary function of the vascular endothelium is the secretion of NO (nitric oxide), which is responsible for vasodilation [ 1 , 2 ] and inhibition...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (1): 69–76.
Published: 01 December 2006
...Zhen Huang; Leif Jansson; Åke Sjöholm Pravastatin, irbesartan and captopril are frequently used in the treatment of patients with Type 2 diabetes. These drugs also exert beneficial metabolic effects, causing an improved glucose tolerance in patients, but the precise mechanisms by which...
Articles
Andrzej Wykretowicz, Przemysław Guzik, Grzegorz Bartkowiak, Tomasz Krauze, Ryszard Kąsinowski, Mieczysław Dziarmaga, Karel H. Wesseling, Henryk Wysocki
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (4): 397–403.
Published: 23 September 2005
... narrowing was estimated by calculation of the Gensini score. All patients underwent a 75 g OGTT (oral glucose tolerance test). IGT (impaired glucose tolerance) or diabetes was present in approx. 60% of patients. The vasodilator response to salbutamol, as a measure of endothelial dysfunction...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (1): 81–84.
Published: 15 December 2004
... 2004 20 9 2004 20 9 2004 The Biochemical Society 2005 glucose tolerance placenta pre-eclampsia pregnancy resistin third trimester Dramatic changes in metabolism occur during pregnancy to meet the demands of fetal growth and to prepare energy reserves for delivery...
Articles
Bruno BALSIGER, Andreas RICKENBACHER, Penelope Jane BODEN, Erwin BIECKER, Janice TSUI, Michael DASHWOOD, Jürg REICHEN, Sidney George SHAW
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 430S–433S.
Published: 01 September 2002
... reduction of the severity of hyperglycaemia. ETA receptor blockade may represent a new therapeutic principle for improving glucose tolerance in Type II diabetes and could be beneficial in alleviating or preventing hyperglycaemia-related secondary complications in this condition. The Seventh...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 89 (3): 321–328.
Published: 01 September 1995
... years and had a body mass index of 27.7 (18.0–41.1) kg/m 2 . They were receiving replacement thyroxine, adrenal steroids and sex hormones and they were growth hormone deficient. Control subjects were matched for age, sex and body mass index. Hypopituitary patients with normal glucose tolerance...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 76 (3): 323–328.
Published: 01 March 1989
... the glucose tolerance curve. 4. In separate experiments, arterialized glucose concentrations were measured after glucose ingestion at 23°C ambient. Antecubital venous glucose concentrations at 33°C ambient were intermediate between venous and arterialized concentrations at 23°C ambient. 5. It is concluded...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (4): 355–361.
Published: 01 October 1988
...W. Scheppach; J. H. Cummings; W. J. Branch; J. Schrezenmeir 1. Dietary fibre has a moderating impact on glucose metabolism. To test the hypothesis that this effect of fibre may be mediated by its breakdown product acetate, oral glucose tolerance tests were carried out in healthy volunteers...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (1): 109–116.
Published: 01 July 1987
... concentrations, in 35 normoglycaemic men with family histories of type 2 diabetes (hereditary group), in 18 subjects with impaired glucose tolerance (IGT) and in 28 normoglycaemic controls. All subjects were non-obese males of comparable age. 2. Earlier findings of increased BP both in normoglycaemic subjects...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (1): 49–55.
Published: 01 July 1986
...-hydroxybutyrate concentrations did not differ significantly. 7. These results support the suggestion that guar improves second-meal tolerance to glucose by decreasing absorption. © 1986 The Biochemical Society and the Medical Research Society 1986 glucose absorption glucose tolerance guar gut hormones...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 68 (2): 151–157.
Published: 01 February 1985
...Richard T. Moxley; William Kingston; Robert C. Griggs 1. The concentration of amino acids in whole blood was measured before and during standard 5 h oral glucose tolerance testing in six male patients with myotonic dystrophy and five normal males. The plasma levels of insulin and glucose were also...
Articles
N. A. Blackburn, J. S. Redfern, H. Jarjis, A. M. Holgate, I. Hanning, J. H. B. Scarpello, I. T. Johnson, N. W. Read
Journal:
Clinical Science
Clin Sci (Lond) (1984) 66 (3): 329–336.
Published: 01 March 1984
...N. A. Blackburn; J. S. Redfern; H. Jarjis; A. M. Holgate; I. Hanning; J. H. B. Scarpello; I. T. Johnson; N. W. Read 1. Experiments were carried out in human volunteers to investigate the mechanism by which guar gum improves glucose tolerance. 2. Guar reduced both plasma glucose and insulin...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 65 (3): 307–312.
Published: 01 September 1983
... classified as ‘normal’ who have been selected for their high thermogenic capacity. 7 3 1983 24 3 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 diet glucose oxidation glucose tolerance obesity thermogenesis Clinical Science (1983) 65,307-312 307...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (6): 601–609.
Published: 01 June 1983
...Richard T. Moxley; Robert C. Griggs; Gilbert B. Forbes; David Goldblatt; Katherine Donohoe 1. The effect of muscle wasting on glucose tolerance was studied. Oral glucose tolerance testing was performed in three groups of wasted patients: myotonic dystrophy (11); amyotrophic lateral sclerosis (10...
Articles
Ove Andersson, Ramon Sivertsson, Rune Sannerstedt, Marie Beckman, Marie Magnusson, Lars Sjöström, Per Björntorp
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 395s–398s.
Published: 01 October 1982
... flow resistance of the hand during hyperaemia was calculated from blood pressure and flow data from venous occlusion plethysmography. 2. In a re-examination 5 years later the same protocol was applied and an oral glucose tolerance test was performed with glucose and insulin determinations. Body...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1975) 49 (5): 473–479.
Published: 01 November 1975
...C. O. Record; R. A. Chase; K. G. M. M. Alberti; R. Williams 1. Intravenous glucose tolerance tests were performed in fourteen patients with mild or moderate liver damage due to paracetamol overdose. 2. In patients managed conservatively there was glucose intolerance associated with a diminished...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1973) 45 (5): 677–690.
Published: 01 November 1973
...C. O. Record; K. G. M. M. Alberti; D. H. Williamson; R. Wright 1. Glucose tolerance and metabolic changes after intravenous glucose were studied in fifteen patients with acute viral hepatitis and in eight patients after recovery. In the acute stage glucose tolerance was significantly impaired...
Articles
Journal:
Clinical Science
Clin Sci (1972) 42 (5): 591–605.
Published: 01 May 1972
... cirrhosis fasting values of serum insulin, growth hormone, blood lactate, pyruvate and glycerol were raised. 5. After corticosteroid therapy hyperinsulinism was found together with a return towards normal of glucose tolerance ( K G , 1·49 + 0·10%/min), ketone bodies, free fatty acids and triglycerides...