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Keywords: glucose tolerance
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Clin Sci (Lond) (2020) 134 (13): 1659–1673.
Published: 01 July 2020
... to muscles to offset the supposed benefit of reduced body weight gain on insulin signalling in this major site for glucose tolerance (or insulin action). The study was conducted in mice exposed to chronic CS followed by either a chow (CH) diet or a high-fat (HF) diet. CS increased triglyceride (TG) levels...
Includes: Supplementary data
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Clin Sci (Lond) (2008) 114 (9): 589–590.
Published: 02 April 2008
... and co-workers report that infusion of glucagon raised fasting plasma glucose concentrations and impaired glucose tolerance over 4 weeks in mice, thus demonstrating a sustained glycaemic effect of hyperglucagonaemia. Nonetheless, compelling evidence that glucagon contributes to the pathogenesis...
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Clin Sci (Lond) (2008) 114 (9): 591–601.
Published: 02 April 2008
...Xiao C. Li; Tang-dong Liao; Jia L. Zhuo Clinical studies have shown that patients with early Type 2 diabetes often have elevated serum glucagon rather than insulin deficiency. Imbalance of insulin and glucagon in favouring the latter may contribute to impaired glucose tolerance, persistent...
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Clin Sci (Lond) (2007) 112 (12): 599–606.
Published: 14 May 2007
... diabetes, to test this hypothesis, we have investigated oxidative stress pathways and DNA damage in patients with IGR and newly diagnosed Type 2 diabetes. The study population consisted of 92 subjects with NGT (normal glucose tolerance), 78 patients with IGR and 113 patients with newly diagnosed diabetes...
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Clin Sci (Lond) (2007) 112 (9): 493–498.
Published: 02 April 2007
... The Biochemical Society 2007 endothelium-derived dilation echocardiography glucose tolerance hyperglycaemia insulin overweight children A primary function of the vascular endothelium is the secretion of NO (nitric oxide), which is responsible for vasodilation [ 1 , 2 ] and inhibition...
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Clin Sci (Lond) (2005) 108 (1): 81–84.
Published: 15 December 2004
... 6 Innes K. E. Wimsatt J. H. McDuffie R. Relative glucose tolerance and subsequent development of hypertension in pregnancy Obstet. Gynecol. 2001 97 905 910 7 Kaaja R. Laivuori H. Laakso M. Tikkanen M. J. Ylikorkala O. Evidence of a state of increased...
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Clin Sci (Lond) (2002) 103 (s2002): 430S–433S.
Published: 01 September 2002
... reduction of the severity of hyperglycaemia. ETA receptor blockade may represent a new therapeutic principle for improving glucose tolerance in Type II diabetes and could be beneficial in alleviating or preventing hyperglycaemia-related secondary complications in this condition. 430S Clinical Science (2002...
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Clin Sci (Lond) (1995) 89 (3): 321–328.
Published: 01 September 1995
... years and had a body mass index of 27.7 (18.0–41.1) kg/m 2 . They were receiving replacement thyroxine, adrenal steroids and sex hormones and they were growth hormone deficient. Control subjects were matched for age, sex and body mass index. Hypopituitary patients with normal glucose tolerance...
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Clin Sci (Lond) (1988) 75 (4): 355–361.
Published: 01 October 1988
...W. Scheppach; J. H. Cummings; W. J. Branch; J. Schrezenmeir 1. Dietary fibre has a moderating impact on glucose metabolism. To test the hypothesis that this effect of fibre may be mediated by its breakdown product acetate, oral glucose tolerance tests were carried out in healthy volunteers...
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Clin Sci (Lond) (1987) 73 (1): 109–116.
Published: 01 July 1987
... concentrations, in 35 normoglycaemic men with family histories of type 2 diabetes (hereditary group), in 18 subjects with impaired glucose tolerance (IGT) and in 28 normoglycaemic controls. All subjects were non-obese males of comparable age. 2. Earlier findings of increased BP both in normoglycaemic subjects...
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Clin Sci (Lond) (1986) 71 (1): 49–55.
Published: 01 July 1986
...-hydroxybutyrate concentrations did not differ significantly. 7. These results support the suggestion that guar improves second-meal tolerance to glucose by decreasing absorption. © 1986 The Biochemical Society and the Medical Research Society 1986 glucose absorption glucose tolerance guar gut hormones...
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Clin Sci (Lond) (1985) 68 (2): 151–157.
Published: 01 February 1985
...Richard T. Moxley; William Kingston; Robert C. Griggs 1. The concentration of amino acids in whole blood was measured before and during standard 5 h oral glucose tolerance testing in six male patients with myotonic dystrophy and five normal males. The plasma levels of insulin and glucose were also...
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Clin Sci (Lond) (1983) 65 (3): 307–312.
Published: 01 September 1983
... classified as ‘normal’ who have been selected for their high thermogenic capacity. 7 3 1983 24 3 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 diet glucose oxidation glucose tolerance obesity thermogenesis Clinical Science (1983) 65,307-312 307...
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Clin Sci (Lond) (1983) 64 (6): 601–609.
Published: 01 June 1983
...Richard T. Moxley; Robert C. Griggs; Gilbert B. Forbes; David Goldblatt; Katherine Donohoe 1. The effect of muscle wasting on glucose tolerance was studied. Oral glucose tolerance testing was performed in three groups of wasted patients: myotonic dystrophy (11); amyotrophic lateral sclerosis (10...
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Clin Sci Mol Med (1975) 49 (5): 473–479.
Published: 01 November 1975
...C. O. Record; R. A. Chase; K. G. M. M. Alberti; R. Williams 1. Intravenous glucose tolerance tests were performed in fourteen patients with mild or moderate liver damage due to paracetamol overdose. 2. In patients managed conservatively there was glucose intolerance associated with a diminished...
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Clin Sci Mol Med (1973) 45 (5): 677–690.
Published: 01 November 1973
...C. O. Record; K. G. M. M. Alberti; D. H. Williamson; R. Wright 1. Glucose tolerance and metabolic changes after intravenous glucose were studied in fifteen patients with acute viral hepatitis and in eight patients after recovery. In the acute stage glucose tolerance was significantly impaired...
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Clin Sci (1972) 42 (5): 591–605.
Published: 01 May 1972
... cirrhosis fasting values of serum insulin, growth hormone, blood lactate, pyruvate and glycerol were raised. 5. After corticosteroid therapy hyperinsulinism was found together with a return towards normal of glucose tolerance ( K G , 1·49 + 0·10%/min), ketone bodies, free fatty acids and triglycerides...