... glucose transport renal physiology Type 2 diabetes mellitus (T2DM) is a major public health concern [ 1 ]. The main feature of T2DM is chronic or periodic hyperglycemia which in turn can lead to progression of the underlying metabolic disease and impair organ functions including cardiovascular...

... glucose transport or suppression of lipolysis was observed. In conclusion, despite the observation that dietary sodium restriction was associated with a median 15% reduction in insulin sensitivity, we found no evidence of a direct effect of AII on insulin action in human adipocytes. Correspondence...

.... By autoradiography, we have also shown that specific binding of glucagon occurs in both the renal cortex and medulla. In addition, using proximal tubule brush-border membrane (BBM) vesicles for studies of glucose transport, we have established that glucagon stimulates glucose uptake via a facilitative GLUT-mediated...

... The Biochemical Society and the Medical Research Society 1996 glucose transport insulin membrane sarcolemma Clinical Science (I 996) 9 I, 591 -599 (Printed in Great Britain) 59 I Effects of limb immobilization on cytochrome c oxidase activity and GLUT4 and GLUT5 protein expression in human skeletal...

...Jonathan B. Meddings; Henrik Westergaard 1. The transport model that best describes intestinal glucose transport in vivo remains unsettled. Three models have been proposed: (1) a single carrier, (2) a single carrier plus passive diffusion, and (3) a two-carrier system. The objectives of the current...

...J. Telch; R. W. Shepherd; D. G. Butler; M. Perdue; J. R. Hamilton; D. G. Gall 1. We studied intestinal glucose transport in pigs during the acute and convalescent phases of an invasive viral enteritis, transmissible gastroenteritis. 2. When diarrhoea was severe 40 h after experimental infection...

... the existence of a co-transport mechanism, whereas the absence of an effect on sodium transport in volume-expanded dogs despite complete inhibition of glucose reabsorption indicates the existence of a sodium-independent component of net proximal tubular glucose transport. 6. Absence of the effect of phlorhizin...

...S.-F. Wen; J. W. Boynar, Jr; R. W. Stoll 1. In order to study the relationship between sodium and glucose transport along the nephron, clearance and micropuncture experiments were performed in 16 dogs before and after administration of diuretics with different sites of action. 2. Administration...