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Keywords: glutathione peroxidase
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Clin Sci (Lond) (2004) 106 (3): 315–319.
Published: 01 March 2004
... dysfunction and oxidative stress. We measured plasma glutathione peroxidase (GSH-Px), an antioxidant enzyme, and the urinary excretion of 8-epi-prostaglandin F 2α (8-PGF 2α ), a free radical-catalysed product from the oxidative modification of arachidonic acid, in 16 healthy subjects (mean age, 30±5 years...
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Clin Sci (Lond) (2001) 100 (5): 543–550.
Published: 05 April 2001
... protection being achieved with 40 nM selenite. The preincubation period was required for selenite to exert this protective effect on endothelial cells. When compared with selenium-deficient cells, the activities of cytoplasmic glutathione peroxidase (GPX-1), phospholipid hydroperoxide glutathione peroxidase...
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Clin Sci (Lond) (2001) 100 (1): 111–116.
Published: 13 December 2000
...L. R. RANGANATH; M. BAINES; N. B. ROBERTS Homocysteine metabolism is increasingly implicated in a diverse group of clinical disorders, including atheromatous vascular disease. We studied the disposition of homocysteine via the trans-sulphuration pathway, plasma glutathione peroxidase (GPx) activity...
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Clin Sci (Lond) (1998) 94 (6): 623–632.
Published: 01 June 1998
...), catalase and glutathione peroxidase] in liver and pancreas of control and streptozotocin-induced diabetic rats at various stages of development of diabetes. 3. Male Sprague—Dawley rats were divided into two groups: group I, control ( n = 42) and group II, diabetic ( n = 42). Each group was further...
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Clin Sci (Lond) (1998) 94 (4): 447–452.
Published: 01 April 1998
... years) and 47 healthy young (29.87 ± 0.53 years) volunteers, we studied the levels of antioxidant enzyme activity (superoxide dismutase, catalase and glutathione peroxidase), protein oxidative damage (as protein carbonyl content) and lysosomal proteolytic activity (cathepsins B, H and L...
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Clin Sci (Lond) (1996) 91 (4): 441–448.
Published: 01 October 1996
...)] and activities of antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase) in aorta, heart and blood of control and streptozotocin-induced diabetic rats at various stages of development of diabetes (0 to 6 weeks). 2. There was no change in the TBARS levels of aorta, heart and blood...
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Clin Sci (Lond) (1995) 89 (6): 637–642.
Published: 01 December 1995
... enzyme. In the elderly, reduced peripheral conversion of thyroxine (T 4 ) to T 3 and overt hypothyroidism are frequently observed. 2. We measured serum selenium and erythrocyte glutathione peroxidase (as indices of selenium status), thyroid hormones and thyroid-stimulating hormone in 109 healthy...
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Clin Sci (Lond) (1989) 77 (5): 495–500.
Published: 01 November 1989
...J. Stone; L. J. Hinks; R. Beasley; S. T. Holgate; B. A. Clayton 1. Selenium is an essential component of glutathione peroxidase (GSH-Px, EC 1.11.1.9), an enzyme which helps protect cells against damage caused by free radicals and hydroperoxides. 2. We report the plasma, whole blood and platelet...
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Clin Sci (Lond) (1987) 73 (5): 525–529.
Published: 01 November 1987
... levels, as well as plasma, whole blood and platelet glutathione peroxidase (GSHPx) activity, were measured in both groups and found to be significantly lower in the group with low Se status. 3. Studies on [ 14 C]arachidonic acid stimulated platelets demonstrated that reduced conversion of the active...
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