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1-16 of 16
Keywords: glutathione peroxidase
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 106 (3): 315–319.
Published: 01 March 2004
... dysfunction and oxidative stress. We measured plasma glutathione peroxidase (GSH-Px), an antioxidant enzyme, and the urinary excretion of 8-epi-prostaglandin F 2α (8-PGF 2α ), a free radical-catalysed product from the oxidative modification of arachidonic acid, in 16 healthy subjects (mean age, 30±5 years...
Articles
Sue MILLER, Simon W. WALKER, John R. ARTHUR, Fergus NICOL, Karen PICKARD, Michelle H. LEWIN, A. Forbes HOWIE, Geoffrey J. BECKETT
Journal:
Clinical Science
Clin Sci (Lond) (2001) 100 (5): 543–550.
Published: 05 April 2001
... protection being achieved with 40 nM selenite. The preincubation period was required for selenite to exert this protective effect on endothelial cells. When compared with selenium-deficient cells, the activities of cytoplasmic glutathione peroxidase (GPX-1), phospholipid hydroperoxide glutathione peroxidase...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2001) 100 (1): 111–116.
Published: 13 December 2000
...L. R. RANGANATH; M. BAINES; N. B. ROBERTS Homocysteine metabolism is increasingly implicated in a diverse group of clinical disorders, including atheromatous vascular disease. We studied the disposition of homocysteine via the trans-sulphuration pathway, plasma glutathione peroxidase (GPx) activity...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2000) 98 (5): 593–599.
Published: 14 April 2000
... effectiveness of organic selenomethionine and inorganic sodium selenite (50 µ g of Se daily for 28 days) in modulating glutathione peroxidase activities in blood cells from 45 healthy men and women, from a U.K. population. Transient and acute changes in lymphocyte, granulocyte and platelet phospholipid...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 94 (6): 623–632.
Published: 01 June 1998
...), catalase and glutathione peroxidase] in liver and pancreas of control and streptozotocin-induced diabetic rats at various stages of development of diabetes. 3. Male Sprague—Dawley rats were divided into two groups: group I, control ( n = 42) and group II, diabetic ( n = 42). Each group was further...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 94 (4): 447–452.
Published: 01 April 1998
... years) and 47 healthy young (29.87 ± 0.53 years) volunteers, we studied the levels of antioxidant enzyme activity (superoxide dismutase, catalase and glutathione peroxidase), protein oxidative damage (as protein carbonyl content) and lysosomal proteolytic activity (cathepsins B, H and L...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1997) 92 (3): 297–305.
Published: 01 March 1997
... studied the mechanisms of these changes by measuring the effect of sulphur amino acid and protein intake on hepatic glutathione synthesis and γ-glutamylcysteine synthetase activity, hepatic and lung glutathione concentrations, glutathione reductase and glutathione peroxidase activities in young rats given...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (4): 441–448.
Published: 01 October 1996
...)] and activities of antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase) in aorta, heart and blood of control and streptozotocin-induced diabetic rats at various stages of development of diabetes (0 to 6 weeks). 2. There was no change in the TBARS levels of aorta, heart and blood...
Articles
Oliviero Olivieri, Domenico Girelli, Margherita Azzini, Anna Maria Stanzial, Carla Russo, Massimiliano Ferroni, Roberto Corrocher
Journal:
Clinical Science
Clin Sci (Lond) (1995) 89 (6): 637–642.
Published: 01 December 1995
... enzyme. In the elderly, reduced peripheral conversion of thyroxine (T 4 ) to T 3 and overt hypothyroidism are frequently observed. 2. We measured serum selenium and erythrocyte glutathione peroxidase (as indices of selenium status), thyroid hormones and thyroid-stimulating hormone in 109 healthy...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1993) 85 (2): 203–211.
Published: 01 August 1993
...N. Meskini; G. Nemoz; P. Chapuy; P. Haond; J. F. Pageaux; E. Vericel; M. Lagarde; A. F. Prigent 1. Since ageing has been associated with a decrease in both immune responses and antioxidant defences, this study was undertaken to compare the glutathione peroxidase activity in peripheral blood...
Articles
Domenico Girelli, Oliviero Olivieri, Anna Maria Stanzial, Margherita Azzini, Antonio Lupo, Patrizia Bernich, Carlo Menini, Linda Gammaro, Roberto Corrocher
Journal:
Clinical Science
Clin Sci (Lond) (1993) 84 (6): 611–617.
Published: 01 June 1993
..., dietary habits and clinical signs of atherosclerosis. 2. Serum selenium concentration and platelet glutathione peroxidase activity were measured in 45 patients with chronic renal failure subdivided into three groups according to the type of treatment: 15 non-dialysed, 15 on haemodialysis, 15 on continuous...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 83 (3): 343–345.
Published: 01 September 1992
...M. Porter; D. J. Pearson; V. J. Suarez-Mendez; A. D. Blann 1. Plasma, platelet and erythrocyte glutathione peroxidase activities and serum lipid concentrations were measured in patients with ischaemic heart disease and matched control subjects. 2. Mean plasma and platelet glutathione peroxidase...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 77 (5): 495–500.
Published: 01 November 1989
...J. Stone; L. J. Hinks; R. Beasley; S. T. Holgate; B. A. Clayton 1. Selenium is an essential component of glutathione peroxidase (GSH-Px, EC 1.11.1.9), an enzyme which helps protect cells against damage caused by free radicals and hydroperoxides. 2. We report the plasma, whole blood and platelet...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (5): 525–529.
Published: 01 November 1987
... levels, as well as plasma, whole blood and platelet glutathione peroxidase (GSHPx) activity, were measured in both groups and found to be significantly lower in the group with low Se status. 3. Studies on [ 14 C]arachidonic acid stimulated platelets demonstrated that reduced conversion of the active...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 58 (3): 211–219.
Published: 01 March 1980
... decrease in the activity of glutathione reductase in patients with secondary iron overload due to multiple transfusion therapy for thalassaemia major. 3. The activities of superoxide dismutase, catalase and glutathione peroxidase were similar in both patient groups. 4. Subcellular fractionation studies...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1974) 47 (6): 643–647.
Published: 01 December 1974
...J. Hopkins; G. R. Tudhope 1. The production of Heinz bodies, after incubation of erythrocytes in the presence of hydrogen peroxide vapour, was significantly greater in erythrocytes with abnormally low glutathione peroxidase (GSH-Px) activity than in cells with normal enzyme activity. 2...