... is uncertain. It has been suggested that it might stem from an inherent deficiency in the protective layer of mucus, linked to differences between mucus glycoproteins (mucins) that are as- sociated with A, B or H activity [6]. This is a credible hypothesis, because the integrity of the mucus layer...

...M. C. Brunisholz; K. L. Lynn; J. S. Hunt 1. Binding between the radiolabeled loop-acting diuretics ([ 14 C]frusemide, [ 14 C]ethacrynic acid and [ 3 H]bumetanide) and human Tamm–Horsfall glycoprotein or human serum albumin in vitro was evaluated by equilibrium dialysis. 2. The diuretic action...

... on to the luminal aspect of the tissue. This method has previously been used to study airway secretions in animals [R. J. Phipps, J. A. Nadel & B. Davis, American Review of Respiratory Disease , (1980) 121 , 359–365]. Evidence is given that the radiolabelled molecules are secretory glycoproteins, probably mucus...

...J. R. Clamp; M. Gough 1. The mucus glycoproteins in meconium from normal infants and from infants having cystic fibrosis with meconium ileus have been studied. 2. Whereas normal meconium contained about 50% protein-bound carbohydrate, the meconium from cystic fibrosis contained only about 10%. 3...

...J. R. Clamp; M. Hartog; J. H. Shelley 1. Abnormalities in glycoprotein metabolism are believed to play a role in diabetic microangiopathy. We have therefore measured the urinary excretion of carbohydrate-containing materials in normal and diabetic subjects. 2. Diabetic subjects were found...

... biological significance. 16 11 1973 © 1974 The Biochemical Society and the Medical Research Society 1974 glycoproteins transferrin electrophoresis neuraminic acid Clinical Science and Molecular Medicine (1914) 46,163-174. STUDIES OF THE METABOLISM O F ASIALOTRANSFERRINS : EVIDENCE...