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1-14 of 14
Keywords: growth factor
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Articles
Tatsuya Usui, Tomoki Sakatsume, Ryo Nijima, Kosuke Otani, Kyosuke Kazama, Tomoka Morita, Satoshi Kameshima, Muneyoshi Okada, Hideyuki Yamawaki
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (8): 539–548.
Published: 02 July 2014
... inhibited platelet-derived growth factor (PDGF)-BB-induced SMC proliferation and migration as determined by bromodeoxyuridine (BrdU) incorporation and a cell counting assay as well as a Boyden chamber assay respectively. DAPK3 siRNA or a pharmacological inhibitor of DAPK3 inhibited PDGF-BB-induced...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (2): 43–52.
Published: 20 September 2011
... of the disease. Numerous studies have shown the key role of the placenta in the pathogenesis of pre-eclampsia. A shift in the sFlt-1 (soluble Fms-like tyrosine kinase-1)/PlGF (placental growth factor) ratio is associated with the disease. Although pre-eclampsia seems to be a clearly defined disease, clinical...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2008) 115 (2): 43–55.
Published: 12 June 2008
... of LIF in mES cells, indicating that not only LIF regulates SFK activity [ 53 ]. Several components present in serum, including FGFs (fibroblast growth factors), Wnts and members of the TGFβ (transforming growth factor β) superfamily have been implicated in regulating self-renewal of mES and hES cells...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (7): 467–477.
Published: 29 February 2008
[email protected] ). 3 9 2007 13 11 2007 15 11 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 angiogenesis growth factor hepatocellular carcinoma (HCC) inflammation liver vascular endothelial growth factor (VEGF) Blood vessels arise from endothelial...
Articles
Rachel E. Wood, Brad E. Sanderson, Christopher D. Askew, Philip J. Walker, Simon Green, Ian B. Stewart
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (6): 401–409.
Published: 14 November 2006
...Rachel E. Wood; Brad E. Sanderson; Christopher D. Askew; Philip J. Walker; Simon Green; Ian B. Stewart Expansion of the capillary network, or angiogenesis, occurs following endurance training. This process, which is reliant on the presence of VEGF (vascular endothelial growth factor...
Articles
Irene J. Andersson, Maria E. Johansson, Anna Wickman, Mohammad Bohlooly-Y, Natalia Klintland, Kenneth Caidahl, Maria Gustafsson, Jan Borén, Li-ming Gan, Göran Bergström
Journal:
Clinical Science
Clin Sci (Lond) (2006) 110 (2): 217–225.
Published: 17 January 2006
... ]. acetylcholine endothelial function growth factor transgenic mouse vasodilation Acromegaly, characterized by excessive secretion of GH (growth hormone), is associated with cardiovascular disease [ 1 ]. Indeed, cardiovascular events are the most common cause of death in acromegalic patients [ 2 , 3...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (4): 293–308.
Published: 22 March 2005
... function even in the absence of physiological levels of circulating androgen. This review will focus on the role of growth factor signalling in prostate cancer progression to androgen independence and thus outline potential molecular areas of intervention to treat prostate cancer progression. Currently...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (1): 1–11.
Published: 15 December 2004
... androgen cancer therapy epithelial cell differentiation growth factor prostate cancer stem cell The incidence of prostate cancer has increased over the past decade and it is now the most common non-cutaneous malignancy in Europe and North America [ 1 ]. Radical prostatectomy and radiation...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 107 (4): 343–354.
Published: 24 September 2004
... apoptosis atherogenesis growth factor inflammation oxidative stress plaque rupture signalling pathway Figure 1 Diagramatic representation of the development of the atherosclerotic lesion (atherogenesis) Phase 1 is the development of the fatty streak from a region of isolated macrophages...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 106 (5): 439–442.
Published: 01 May 2004
...Yoshinori SEKO; Shuichi FUKUDA; Ryozo NAGAI Angiogenesis is controlled by anti-angiogenic factors as well as by angiogenic factors, such as VEGF (vascular endothelial growth factor) and HGF (hepatocyte growth factor). Endostatin, a potent endogenous angiogenesis inhibitor, is known to inhibit...
Articles
Rafael SIMÓ, Cristina HERNÁNDEZ, Rosa M. SEGURA, José GARCÍA-ARUMÍ, Laura SARAROLS, Rosa BURGOS, Ana CANTÓN, Jordi MESA
Journal:
Clinical Science
Clin Sci (Lond) (2003) 104 (3): 223–230.
Published: 30 January 2003
...Rafael SIMÓ; Cristina HERNÁNDEZ; Rosa M. SEGURA; José GARCÍA-ARUMÍ; Laura SARAROLS; Rosa BURGOS; Ana CANTÓN; Jordi MESA The aim of the study was to evaluate the vitreous levels of free insulin-like growth factor 1 (IGF-1) in patients with proliferative diabetic retinopathy (PDR). For this, a total...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2000) 99 (6): 561–567.
Published: 21 November 2000
... specific mRNA transcripts for the recently cloned human LPA-receptors, endothelial differentiation gene (Edg)-2 and Edg-4 (Edg-2 ≫ Edg-4) by reverse transcription-PCR in PT cells. Our data suggest that LPA may behave as a local growth factor in PT cells following tubular injury. exfoliation growth...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1999) 96 (4): 431–436.
Published: 01 April 1999
...Chiyoko N. INOUE; Murray EPSTEIN; Hayley G. FORSTER; Osamu HOTTA; Yoshiaki KONDO; Kazuie IINUMA The last decade has witnessed a phenomenal increase in our understanding of the biological role of lysophosphatidic acid (LPA) and has led to an appreciation of this critical serum-derived growth factor...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 89 (1): 53–57.
Published: 01 July 1995
...ART Ationu; Michael Burch; Donald Singer; Marc De Leval; Bruce Whitehead; Nicholas Carter 1. Insulin-like growth factor I is a major mediator of growth-promoting activities. We studied the ventricular insulin-like growth factor I gene expression at mRNA and peptide levels in 24 heart transplant...