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Keywords: heart rate variabilityClose
Sarah E. Haskell, Veronica Peotta, Benjamin E. Reinking, Catherine Zhang, Vivian Zhu, Elizabeth J. Kenkel, Robert D. Roghair
Clin Sci (Lond) (2016) 130 (8): 613–623.
Published: 08 March 2016
... the protective effects of oestrogen replacement therapy. autonomic developmental origins echocardiography heart rate variability • Sexual dimorphism has been observed in the developmental origins of cardiovascular disease, with young adult women relatively protected from perinatal GR-induced...
Clin Sci (Lond) (2015) 129 (10): 885–893.
Published: 01 September 2015
... exercise heart rate variability oestrogen • Low HRV is associated with increased risk of cardiac events in both healthy and diseased populations. Oestrogen deficiency due to menopause is associated with attenuated HRV in association with decreased vagal modulation. We examined the influence...
Djordje G. Jakovljevic, Kate Hallsworth, Pawel Zalewski, Christian Thoma, Jacek J. Klawe, Christopher P. Day, Julia Newton, Michael I. Trenell
Clin Sci (Lond) (2013) 125 (3): 143–149.
Published: 12 April 2013
... 2013 blood pressure variability exercise heart rate variability non-alcoholic fatty liver disease (NAFLD) • Prevalence of autonomic dysfunction in patients with NAFLD is high, but therapies to improve autonomic regulation are limited. The present study defines the impact of a short...
Clin Sci (Lond) (2012) 122 (7): 323–328.
Published: 07 December 2011
... reactions and excessive sympathetic responses, all of which are inhibited by vagal nerve activity. Efferent vagal activity that can be non-invasively measured by HRV (heart rate variability), derived from an ECG, is inversely related to all three basic mechanisms, to various risk factors (e.g. diabetes...
Clin Sci (Lond) (2011) 121 (5): 215–222.
Published: 20 May 2011
...Matthijs Kox; Jan C. Pompe; Johannes G. van der Hoeven; Cornelia W. Hoedemaekers; Peter Pickkers HRV (heart rate variability) analysis is a widely employed method to assess cardiac autonomic nervous system activity. Accurate HRV measurement is critical to its value as a diagnostic and prognostic...
Clin Sci (Lond) (2010) 119 (8): 313–322.
Published: 06 July 2010
... is a marker of atherosclerotic risk, so we also assessed relationships between ATBF and a marker of atherosclerosis, common carotid artery IMT (intima-media thickness). As ATBF is responsive to sympatho-adrenal stimuli, we also investigated relationships with HRV (heart rate variability). A total of 79...
Roberto Maestri, Grzegorz Raczak, Ludmila Danilowicz-Szymanowicz, Antoni Torunski, Adam Sukiennik, Jacek Kubica, Maria Teresa La Rovere, Gian Domenico Pinna
Clin Sci (Lond) (2010) 118 (3): 195–201.
Published: 01 February 2010
...Roberto Maestri; Grzegorz Raczak; Ludmila Danilowicz-Szymanowicz; Antoni Torunski; Adam Sukiennik; Jacek Kubica; Maria Teresa La Rovere; Gian Domenico Pinna Despite a well-established prognostic value in cardiac patients, HRV (heart rate variability) indexes have been used little in the clinical...
Simonetta Genovesi, Daniela M. Prata Pizzala, Massimo Pozzi, Laura Ratti, Maria Milanese, Federico Pieruzzi, Antonio Vincenti, Andrea Stella, Giuseppe Mancia, Marco Stramba-Badiale
Clin Sci (Lond) (2009) 116 (12): 851–859.
Published: 14 May 2009
... patients underwent a 24-h ECG Holter recording. The 24-h mean of QT intervals corrected for heart rate (termed QTc) and the slope of the regression line QT/RR were calculated. HRV (heart rate variability), plasma calcium and potassium concentration and HVPG (hepatic venous pressure gradient) were measured...
Gian Domenico Pinna, Roberto Maestri, Antoni Torunski, Ludmila Danilowicz-Szymanowicz, Malgorzata Szwoch, Maria Teresa La Rovere, Grzegorz Raczak
Clin Sci (Lond) (2007) 113 (3): 131–140.
Published: 02 July 2007
...Gian Domenico Pinna; Roberto Maestri; Antoni Torunski; Ludmila Danilowicz-Szymanowicz; Malgorzata Szwoch; Maria Teresa La Rovere; Grzegorz Raczak Despite its extensive use in physiological and clinical research, the analysis of HRV (heart rate variability) is still poorly supported by rigorous...
Clin Sci (Lond) (2007) 113 (3): 129–130.
Published: 02 July 2007
...Gavin Sandercock HRV (heart rate variability) is a non-invasive maker of cardiac autonomic modulation utilized in many hundreds of scientific studies each year. The reliability of heart rate variability has been frequently investigated yet remains poorly quantified. Assessing the reliability...
Clin Sci (Lond) (2007) 112 (8): 449–456.
Published: 13 March 2007
...Robert P. Nolan; Graham J. Reid; Peter H. Seidelin; Herbert K. Lau Systemic inflammation is associated with sympathetic cardiac activation and decreased HRV (heart rate variability) in subjects at high risk of CAD (coronary artery disease). In the present study, we examined the influence...
Clin Sci (Lond) (2005) 108 (3): 215–216.
Published: 18 February 2005
...Philippe van de BORNE In this issue of Clinical Science , Trang and co-workers report the results of short-term blood pressure and heart rate variability measurements in patients with congenital central hypoventilation syndrome (CCHS). The results reveal that these young patients disclose signs...
Clin Sci (Lond) (2005) 108 (3): 225–230.
Published: 18 February 2005
...Ha TRANG; Arlette GIRARD; Dominique LAUDE; Jean-Luc ELGHOZI The effect of CCHS (congenital central hypoventilation syndrome, or Ondine's curse) on short-term BP (blood pressure) and HR (heart rate) variability was evaluated in 16-year-old subjects presenting a form of CCHS requiring night...
Clin Sci (Lond) (2005) 108 (2): 93–99.
Published: 21 January 2005
...Daniela MANZELLA; Giuseppe PAOLISSO CAN (cardiac autonomic neuropathy) is a common complication of diabetes. Meta-analyses of published data demonstrate that reduced cardiovascular autonomic function, as measured by heart rate variability, is strongly associated with an increased risk of silent...
Gianfranco PICCIRILLO, Damiano MAGRÌ, Camilla NASO, Silvia di CARLO, Antonio MOISÈ, Tiziana DE LAURENTIS, Alessia TORRINI, Sabrina MATERA, Marialuce NOCCO
Clin Sci (Lond) (2004) 107 (2): 183–190.
Published: 27 July 2004
...Gianfranco PICCIRILLO; Damiano MAGRÌ; Camilla NASO; Silvia di CARLO; Antonio MOISÈ; Tiziana DE LAURENTIS; Alessia TORRINI; Sabrina MATERA; Marialuce NOCCO A decreased LFP (low-frequency power) spectral component of HRV [HR (heart rate) variability] is a risk factor for sudden death in patients...
Frédéric ROCHE, Emilia SFORZA, David DUVERNEY, Jean-René BORDERIES, Vincent PICHOT, Odile BIGAIGNON, Gilles ASCHER, Jean-Claude BARTHÉLÉMY
Clin Sci (Lond) (2004) 107 (1): 105–110.
Published: 23 June 2004
... system ECG Holter monitoring heart rate variability obstructive sleep apnoea/hypopnoea syndrome Figure 2 ROC curve analysis for the identification of OSAHS with AHI threshold increments from AHI ≥10 (upper panel), ≥20 (middle panel) and ≥30 (lower panel) In group 2, neither BMI nor...
Hartmut SCHÄCHINGER, Johannes PORT, Stuart BRODY, Lilly LINDER, Frank H. WILHELM, Peter R. HUBER, Daniel COX, Ulrich KELLER
Clin Sci (Lond) (2004) 106 (6): 583–588.
Published: 01 June 2004
... 2004 The Biochemical Society 2004 autonomic nervous system glucose heart rate variability hypoglycaemia impedance cardiography Clinical Science (2004) 106, 583 588 (Printed in Great Britain) 583 Increased high-frequency heart rate variability during insulin-induced hypoglycaemia in healthy...
Clin Sci (Lond) (2004) 106 (1): 61–66.
Published: 01 January 2004
...M. A. KOWALEWSKI; M. URBAN Autonomic nervous tests and heart rate variability (HRV) have been used to assess cardiac autonomic function and to evaluate long-term prognosis. The aim of this study was to evaluate the short- and long-term reproducibility of HRV parameters and autonomic nervous tests...
Clin Sci (Lond) (2003) 105 (1): 119–126.
Published: 01 July 2003
...Giosuè GULLI; Victoria L. COOPER; Victoria CLAYDON; Roger HAINSWORTH Correspondence: Dr Giosuè Gulli (e-mail GiosueGulli@yahoo.it ). 12 11 2002 26 2 2003 2 4 2003 2 4 2003 © 2003 The Biochemical Society 2003 baroreflex heart rate variability syncope...
Clin Sci (Lond) (2002) 102 (4): 465–473.
Published: 18 March 2002
...) and in healthy subjects (controls), as well as comparing the values of BRS parameters with parameters of heart rate variability (HRV) and blood pressure variability (BPV). ECG, continuous blood pressure and respiration curves were recorded for 30min in 27 DCM patients and 27 control subjects. The Dual Sequence...
Clin Sci (Lond) (2002) 102 (4): 397–402.
Published: 05 March 2002
... patients [NYHA class II-III; mean age 52 years (range 38-67 years)] and 12 age/sex-matched healthy control subjects [mean age 50 years (range 36-62 years)] were studied. Heart rate variability and baroreflex sensitivity were measured during inhibition of endogenous NO production with N G -monomethyl- l...
Tapio NOUSIAINEN, Esko VANNINEN, Esa JANTUNEN, Jouko REMES, Eira RITANEN, Olli VUOLTEENAHO, Juha HARTIKAINEN
Clin Sci (Lond) (2001) 101 (6): 601–607.
Published: 26 October 2001
... ventriculography, frequency domain analysis of heart rate variability (HRV), and plasma noradrenaline and natriuretic peptide measurements were performed in 27 adult lymphoma patients at baseline and after cumulative doxorubicin doses of 200, 400 and 500mg/m 2 . The left ventricular ejection fraction (LVEF...
J. C. VAILE, S. CHOWDHARY, F. OSMAN, H. F. ROSS, J. FLETCHER, W. A. LITTLER, J. H. COOTE, J. N. TOWNEND
Clin Sci (Lond) (2001) 101 (6): 559–566.
Published: 24 October 2001
... compared the effects of candesartan and placebo on baroreflex sensitivity and on heart rate variability at rest, during stress and during 24h monitoring. Acute effects were assessed 4h after oral candesartan (8mg) and chronic effects after 4 weeks of treatment (dose titrated to 16mg daily). The study group...
Duminda N. WIJEYSUNDERA, Gary C. BUTLER, Shin-ichi ANDO, Michael J. POLLARD, Peter PICTON, John S. FLORAS
Clin Sci (Lond) (2001) 100 (3): 303–309.
Published: 31 January 2001
.... During the course of our investigation of sympathetic nervous system responses to lower body negative press- ure (LBNP) in healthy, middle-aged men, symptoms or Key words : baroreceptor reflex, central venous pressure, heart rate variability, microneurography, sympathetic nervous system. Abbreviations...
Clin Sci (Lond) (2001) 100 (1): 43–46.
Published: 13 December 2000
...S. W. LORD; R. R. SENIOR; M. DAS; A. M. WHITTAM; A. MURRAY; J. M. MCCOMB Heart rate variability is a measure of autonomic nervous influence on the heart. It has been suggested that it could be used to detect autonomic reinnervation to the transplanted heart, but the reproducibility...
Cornelius KEYL, Martin DAMBACHER, Annette SCHNEIDER, Claudio PASSINO, Ulrike WEGENHORST, Luciano BERNARDI
Clin Sci (Lond) (2000) 99 (2): 113–124.
Published: 10 July 2000
... ). 27 10 1999 6 3 2000 31 3 2000 The Biochemical Society and the Medical Research Society © 2000 2000 autonomic nervous system baroreceptors blood pressure heart rate variability respiration 113Clinical Science (2000) 99, 113 124 (Printed in Great Britain...
Giuseppe PAOLISSO, Daniela MANZELLA, Maria Rosaria RIZZO, Michelangela BARBIERI, Gina VARRICCHIO, Antonio GAMBARDELLA, Michele VARRICCHIO
Clin Sci (Lond) (2000) 98 (2): 129–136.
Published: 04 January 2000
... by continuous recording of heart rate variability by the Holter technique and by venous occlusion plethysmography respectively. At baseline, healthy subjects had the highest values for total spectral power and the low-frequency (LF) component, and the lowest value for the high-frequency (HF) component...
Giuseppe PAOLISSO, Daniela MANZELLA, Michelangela BARBIERI, Maria Rosaria RIZZO, Antonio GAMBARDELLA, Michele VARRICCHIO
Clin Sci (Lond) (1999) 97 (5): 579–584.
Published: 28 September 1999
...Giuseppe PAOLISSO; Daniela MANZELLA; Michelangela BARBIERI; Maria Rosaria RIZZO; Antonio GAMBARDELLA; Michele VARRICCHIO Healthy centenarians have better anthropometric, endocrine, metabolic and immunological parameters than aged subjects (> 75 years old). Heart rate variability (HRV) has been...
Julian C. VAILE, Janine FLETCHER, Muzahim AL-ANI, Hamish F. ROSS, William A. LITTLER, John H. COOTE, Jonathan N. TOWNEND
Clin Sci (Lond) (1999) 97 (5): 585–593.
Published: 28 September 1999
... whether such an effect is evident in healthy humans, by examining the effects of lipophilic and hydrophilic agents on heart rate variability and cardiac vagal reflexes. A total of 20 healthy volunteers took part in the study. Autonomic studies were performed after 72 h of treatment with placebo, atenolol...
Roberto COLOMBO, Giorgio MAZZUERO, Gianluca SPINATONDA, Paola LANFRANCHI, Pantaleo GIANNUZZI, Piotr PONIKOWSKI, Andrew J. S. COATS, Giuseppe MINUCO
Clin Sci (Lond) (1999) 97 (4): 503–513.
Published: 17 September 1999
... and the Medical Research Society © 1999 1999 baroreceptor reflex sensitivity heart failure heart rate variability spectral analysis 503Clinical Science (1999) 97, 503 513 (Printed in Great Britain) Comparison between spectral analysis and the phenylephrine method for the assessment of baroreflex...
Gerard A. RONGEN, Steven C. BROOKS, Michael J. POLLARD, Shin-ichi ANDO, Hilmi R. DAJANI, Catherine F. NOTARIUS, John S. FLORAS
Clin Sci (Lond) (1999) 96 (6): 597–604.
Published: 07 May 1999
... in humans that overrides its direct negative chronotropic effect. We tested the hypothesis that adenosine increases heart rate by suppressing parasympathetic and augmenting sympathetic components of heart rate variability. High-frequency ( P H ; 0.15-0.50 Hz) and low-frequency ( P L ; 0.05-0.15 Hz...
Catherine F. NOTARIUS, Gary C. BUTLER, Shin-ichi ANDO, Michael J. POLLARD, Beverley L. SENN, John S. FLORAS
Clin Sci (Lond) (1999) 96 (6): 557–565.
Published: 28 April 1999
...Catherine F. NOTARIUS; Gary C. BUTLER; Shin-ichi ANDO; Michael J. POLLARD; Beverley L. SENN; John S. FLORAS The concept that spectral analysis of heart rate variability (HRV) can estimate cardiac sympathetic nerve traffic in subjects with both normal and impaired left ventricular systolic function...
Paolo PANCERA, Stefano SANSONE, Barbara PRESCIUTTINI, Luciano MONTAGNA, Silvia CERÙ, Claudio LUNARDI, Alessandro LECHI
Clin Sci (Lond) (1998) 96 (1): 49–57.
Published: 01 January 1999
... the sympathetic (low-frequency) and vagal (high-frequency) components of heart rate variability, in supine and upright positions, in 10 patients with systemic sclerosis, 12 patients with primary Raynaud's phenomenon and 14 controls. We also analysed lung function in order to evaluate a possible link between heart...
Luciano BERNARDI, Claudio PASSINO, Giammario SPADACINI, Alessandro CALCIATI, Robert ROBERGS, Richard GREENE, Emilia MARTIGNONI, Inder ANAND, Otto APPENZELLER
Clin Sci (Lond) (1998) 95 (5): 565–573.
Published: 01 November 1998
... lost by at least 1 year's sea-level residence. Correspondence : Dr Luciano Bernardi. 19 2 1998 1 6 1998 18 6 1998 The Biochemical Society and the Medical Research Society © 1998 1998 autonomic nervous system baroreflex heart rate variability high altitude...
Nicolette T. C. URSEM, Piet C. STRUIJK, Wim C. J. HOP, Edward B. CLARK, Bradley B. KELLER, Juriy W. WLADIMIROFF
Clin Sci (Lond) (1998) 95 (5): 539–545.
Published: 01 November 1998
...Nicolette T. C. URSEM; Piet C. STRUIJK; Wim C. J. HOP; Edward B. CLARK; Bradley B. KELLER; Juriy W. WLADIMIROFF 1. The aim of this study was to define from umbilical artery flow velocity waveforms absolute peak systolic and time-averaged velocity, fetal heart rate, fetal heart rate variability...
Clin Sci (Lond) (1998) 95 (3): 269–275.
Published: 01 September 1998
... The Biochemical Society and the Medical Research Society © 1998 1998 baroreflex blood volume regulating hormones heart rate variability fractal non-hypotensive haemorrhage 269Clinical Science (1998) 95, 269 275 (Printed in Great Britain) Human cardiovascular variability, baroreflex and hormonal...
Andrea Scaramuzza, Fabrizio Salvucci, Stefano Leuzzi, Alberto Radaelli, Giuseppe d'Annunzio, Pietro Fratino, Renata Lorini, Luciano Bernardi
Clin Sci (Lond) (1998) 94 (6): 615–621.
Published: 01 June 1998
... that autonomic abnormalities are likely to develop at an older age. 5 1 1998 28 1 1998 © 1998 The Biochemical Society and the Medical Research Society 1998 adolescents autonomic neuropathy baroreflex sensitivity cardiovascular reflexes heart rate variability power spectral analysis...
Daniel A. Duprez, Marc L. De Buyzere, Benny Drieghe, Friedl Vanhaverbeke, Youri Taes, Walter Michielsen, Denis L Clement
Clin Sci (Lond) (1998) 94 (1): 57–63.
Published: 01 January 1998
... 1998 blood pressure chronic fatigue syndrome heart rate variability power spectral analysis psychosomatic distress Clinical Science (I 998) 94,57-63 (Printed in Great Britain) 57 Long- and short-term blood pressure and RR-interval variability and psychosomatic distress in chronic fatigue...
Clin Sci (Lond) (1997) 93 (4): 299–308.
Published: 01 October 1997
...Kuniaki Otsuka; Germaine Cornelissen; Franz Halberg 1. The fractal scaling of heart rate variability, gauged by the correlation dimension (CD), is hypothesized to be characterized by a time structure (chronome), which in health shows differences as a function of gender and age. 2. From 24 h Holter...
Michel White, Marc Courtemanche, Duncan J. Stewart, Mario Talajic, Ethel Mikes, Peter Cernacek, Pascal Vantrimpont, Diane Leclerc, Lizanne Bussières, Jean L. Rouleau
Clin Sci (Lond) (1997) 93 (4): 309–316.
Published: 01 October 1997
... volunteers (68 ± 7 years) underwent a 30 min head-up tilt test at 60°. Haemodynamics were measured every 5 min and blood samples for neurohormone measurement were drawn at baseline, 5, 10, 15 and 30 min into the test. Heart rate variability was analysed in 5 min segments at the baseline, and during the test...
Clin Sci (Lond) (1997) 92 (4): 345–349.
Published: 01 April 1997
... a difference in gender-based development as noted in the separate context of fetal lung maturation. 21 11 1996 28 11 1996 © 1997 The Biochemical Society and the Medical Research Society 1997 complexity electrocardiogram fetus gender heart rate variability Clinical Science (1997...
Gervais Tougas, Markad Kamath, Geena Watteel, Debbie Fitzpatrick, Ernest L. Fallen, Richard H. Hunt, Adrian R. M. Upton
Clin Sci (Lond) (1997) 92 (2): 167–174.
Published: 01 February 1997
... on the power spectrum of beat-to-beat heart rate variability in male volunteers. 2. In 14 healthy volunteers, beat-to-beat heart rate variability was compared at rest and during oesophageal stimulation, using either electrical (200 μs, 16 mA, 0.2 Hz) or mechanical (0.5 s, 14 ml, 0.2 Hz) stimuli. The power...
Piotr Ponikowski, Massimo Piepoli, Aham A. Amadi, Tuan Peng Chua, Derek Harrington, Maurizio Volterrani, Roberto Colombo, Giorgio Mazzuero, Amerigo Giordano, Andrew J. S. Coats
Clin Sci (Lond) (1996) 91 (4): 391–398.
Published: 01 October 1996
...Piotr Ponikowski; Massimo Piepoli; Aham A. Amadi; Tuan Peng Chua; Derek Harrington; Maurizio Volterrani; Roberto Colombo; Giorgio Mazzuero; Amerigo Giordano; Andrew J. S. Coats 1. In patients with chronic heart failure, heart rate variability is reduced with relative preservation of very-low...
Clin Sci (Lond) (1996) 91 (2): 201–208.
Published: 01 August 1996
...Peter Walter Kamen; Henry Krum; Andrew Maxwell Tonkin 1. Time domain summary statistics and frequency domain parameters can be used to measure heart rate variability. More recently, qualitative methods including the Poincaré plot have been used to evaluate heart rate variability. The aim...
John E. Sanderson, Leata Y. C. Yeung, Dickens T. K. Yeung, Richard L. C. Kay, Brian Tomlinson, J. A. J. H. Critchley, Kam S. Woo, Luciano Bernardi
Clin Sci (Lond) (1996) 91 (1): 35–43.
Published: 01 July 1996
.... The low-frequency/high-frequency ratio derived from power spectral analysis of heart rate variability has been proposed as a non-invasive method to assess sympatho-vagal balance. However, the effects of different respiratory rates or posture are rarely accounted for, but may be relevant in patients...
Luciano Bernardi, Alberto Radaelli, Pier Luigi Solda, Andrew J. S. Coats, Martin Reeder, Alessandro Calciati, Christopher S. Garrard, Peter Sleight
Clin Sci (Lond) (1996) 90 (5): 345–355.
Published: 01 May 1996
... pressure. 16 1 1995 21 1 1996 25 1 1996 © 1996 The Biochemical Society and the Medical Research Society 1996 arterial baroreflexes autonomic nervous system heart rate variability microcirculation postural changes power spectrum skin blood flow Clinical Science (1996) 90...
Clin Sci (Lond) (1996) 90 (3): 235–241.
Published: 01 March 1996
...M. Al-Ani; A. S. Forkins; J. N. Townend; J. H. Coote 1. The influence of central inspiratory drive on heart rate variability was investigated in young human subjects using power spectral analysis of R—R intervals. 2. The area of the high-frequency component occurring at the respiratory frequency...
Lee A. Fleisher, Steven M. Frank, Daniel I. Sessler, Christi Cheng, Takashi Matsukawa, Carole A. Vannier
Clin Sci (Lond) (1996) 90 (2): 97–103.
Published: 01 February 1996
...Lee A. Fleisher; Steven M. Frank; Daniel I. Sessler; Christi Cheng; Takashi Matsukawa; Carole A. Vannier 1. Heart rate variability is modulated by multiple control systems, including autonomic and hormonal systems. Long-term variability, i.e. the very low-frequency band of the power spectra, has...
Clin Sci (Lond) (1995) 89 (2): 155–164.
Published: 01 August 1995
...Massimo Piepoli; Stamatis Adamopoulos; Luciano Bernardi; Peter Sleight; Andrew J. S. Coats 1. Heart rate variability can be used to evaluate autonomic balance, but it is unclear how inotropic therapy may affect the findings. The aim of the study was to assess whether heart rate variability can...
Peter Sleight, Maria Teresa La Rovere, Andrea Mortara, Gianni Pinna, Roberto Maestri, Stefano Leuzzi, Beatrice Bianchini, Luigi Tavazzi, Luciano Bernardi
Clin Sci (Lond) (1995) 88 (1): 103–109.
Published: 01 January 1995
... nervous system baroreflex sensitivity heart failure heart rate variability Clinical Science (1995) 88, 103409 (Printed in Great Britain) I03 Physiology and pathophysiology of heart rate and blood pressure variability in humans: is power spectral analysis largely an index of baroreflex gain? Peter...