Skip Nav Destination
Close Modal
Update search
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
NARROW
Format
Subjects
Article Type
Date
Availability
1-3 of 3
Keywords: hedgehog
Close
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Sort by
Articles
Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (8): 953–970.
Published: 29 April 2019
...Masaru Katoh Hedgehog signals are transduced through Patched receptors to the Smoothened (SMO)-SUFU-GLI and SMO-Gi-RhoA signaling cascades. MTOR-S6K1 and MEK-ERK signals are also transduced to GLI activators through post-translational modifications. The GLI transcription network up-regulates target...
Articles
Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation
Available to PurchaseImad Al Ghouleh, Sanghamitra Sahoo, Daniel N. Meijles, Jefferson H. Amaral, Daniel S. de Jesus, John Sembrat, Mauricio Rojas, Dmitry A. Goncharov, Elena A. Goncharova, Patrick J. Pagano
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (15): 2019–2035.
Published: 17 July 2017
... morphogenetic protein (BMP) antagonist Gremlin1 (Grem1). In HPAEC, hypoxia induced Nox1 subunit expression, assembly, and oxidase activity leading to elevation in sonic hedgehog (SHH) and Grem1 expression. Nox1 gene silencing abrogated this cascade. Moreover, loss of either Nox1, SHH or Grem1 attenuated hypoxia...
Articles
Osteopontin is up-regulated in chronic hepatitis C and is associated with cellular permissiveness for hepatitis C virus replication
Available to PurchaseSteve S. Choi, Lee C. Claridge, Ravi Jhaveri, Marzena Swiderska-Syn, Paul Clark, Ayako Suzuki, Thiago A. Pereira, Zhiyong Mi, Paul C. Kuo, Cynthia D. Guy, Fausto E. L. Pereira, Anna Mae Diehl, Keyur Patel, Wing-Kin Syn
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (12): 845–855.
Published: 26 February 2014
...Steve S. Choi; Lee C. Claridge; Ravi Jhaveri; Marzena Swiderska-Syn; Paul Clark; Ayako Suzuki; Thiago A. Pereira; Zhiyong Mi; Paul C. Kuo; Cynthia D. Guy; Fausto E. L. Pereira; Anna Mae Diehl; Keyur Patel; Wing-Kin Syn OPN (osteopontin)) is a Hh (Hedgehog)-regulated cytokine that is up-regulated...
