... in male SHR 7 days post-IR. To assess the role of vascular congestion on impaired recovery following IR, additional male and female SHR were pretreated with heparin (200 U/kg) prior to IR. Heparin pretreatment reduced IR-induced vascular congestion and improved renal function in male SHR 7 days post-IR...

... in the plasma concentration of antithrombin. Therefore the aim of the present study was to test the hypothesis that intravenous administration of recombinant human antithrombin in combination with aerosolized heparin will ameliorate acute lung injury in sheep exposed to cutaneous burn and smoke inhalation...

... in muscle capillarity between the groups. The HD patients were, however, administered heparin as a routine part of the dialysis therapy. The possibility is discussed that heparin in combination with mild anaemia and acidosis may have augmented angiogenesis in the HD patients. It would seem logical...

...Lokpal BHATIA; Gerald J. CLESHAM; Delphine R. TURNER Correspondence: Dr Lokpal Bhatia (email [email protected] ). 4 6 2004 2 7 2004 2 7 2004 The Biochemical Society 2004 endostatin heparin hepatocyte growth factor (HGF) myocardial infarction vascular...

... in obese subjects, confirming previous observations. In the second study, in which carbohydrate-stimulated GLP-1 responses were again evaluated in obese and lean women, circulating NEFA levels were modulated using either heparin (to increase serum NEFA) or acipimox (to reduce serum NEFA). Treatment...

...) hyporeactivity to noradrenaline. In rats infused with lipopolysaccharide and heparin (1 U min −1 kg −1 , 0.4 ml/h) or hirudin (2.2 mg ml −1 kg −1 , 0.8 ml/h), vasopressor responses to noradrenaline were not different from those after infusion of lipopolysaccharide alone. Aortic rings taken from rats receiving...

... on polyethylene glycol 4000 permeability, although it still caused a significant decrease in colonic fluid absorption from 48.83 ± 2.98 ( n = 7) (control) to 31.41 ± 2.08 (n = 5) μl h −1 cm −2 ( P <0.01). 4. Low-molecular-mass heparin (600 units/ml) prevented the spermine (5 mmol/l)- and whole-semen-induced...

...R. L. Walsh; T. J. Dillon; R. Scicchitano; G. McLennan 1. Heparin and heparan sulphate strongly inhibited human leucocyte elastase activity in an automated assay using the soluble substrate, n -succinyl-( l -alanine) 3 - p -nitroanilide (50% inhibition of 250 μl of 10 μg of human leucocyte elastase...

...Daisy K. Y. Shum; Christine Baylis; John E. Scott 1. Commercial heparin and acid glycosaminoglycans (AGAG) prepared from normal female human urine were tritiated catalytically in aqueous solution. Nasal septal chondroitin sulphate was tritiated by NaB 3 H 4 reduction of the aldehydes produced...

... histology were not influenced significantly by the presence or absence of histological or radiological evidence of parathyroid overactivity or of osteomalacia, nor by differences in the causes of renal disease. 5. Loss of metacarpal cortical bone correlated with heparin consumption during haemodialysis...

...C. Thomson; C. D. Forbes; C. R. M. Prentice 1. Heparin has been shown to increase platelet aggregation by ADP and adrenaline and to enhance the platelet release reaction when tested in citrated platelet-rich plasma (P.R.P.). This activity is present when heparin is added to P.R.P. or when P.R.P...