... (S1P) are associated with disrupted endothelial cell (EC) barriers, lymphopenia and reduced responsivity to hypoxia. Total S1P levels were also reduced in 23 critically ill patients with coronavirus disease 2019 (COVID-19), and the two main S1P carriers, serum albumin (SA) and high-density lipoprotein...

...Jack D. Beazer; Patamat Patanapirunhakit; Jason M.R. Gill; Delyth Graham; Helen Karlsson; Stefan Ljunggren; Monique T. Mulder; Dilys J. Freeman High-density lipoprotein (HDL) is a circulating complex of lipids and proteins known primarily for its role in reverse cholesterol transport and consequent...

...Nicholas Hui; Philip J. Barter; Kwok-Leung Ong; Kerry-Anne Rye Metabolic disorders are associated with an increased risk of cardiovascular disease (CVD), and are commonly characterized by a low plasma level of high-density lipoprotein cholesterol (HDL-C). Although cholesterol lowering medications...

... transport). HDL (high-density lipoprotein) has been reported to transport BAs. We therefore investigated the effects of monogenic disturbances in human HDL metabolism on serum concentrations and lipoprotein distributions of the major 15 BA species and their precursor C4 (7α-hydroxy-4-cholesten-3-one...

...Anne E. Barden; Janet A. Dunstan; Lawrence J. Beilin; Susan L. Prescott; Trevor A. Mori n −3 Fatty acids derived from fish oil reduce plasma triacylglycerols (triglycerides) and increase HDL-C (high-density lipoprotein cholesterol); however, the effect of n −3 fatty acid supplementation during...

... plasma protein carbonyls and comparing antioxidant capacity of HDL (high-density lipoprotein) as pertaining to PON1 (paraoxonase 1) activity and in vitro removal of LPO (lipid peroxides). ESRD subjects on haemodialysis ( n =22), Type I diabetes subjects ( n =20) without vascular complications and healthy...

...Sara P. DEAKIN; Richard W. JAMES PON1 (paraoxonase-1) is an HDL (high-density lipoprotein)-associated enzyme capable of hydrolysing diverse substrates from OP (organophosphate) toxins to oxidized phospholipids. As such, it has been linked with both the prevention of OP poisoning and inhibition...

... and the plasma antioxidant status in a group of soccer players engaged in a regular training programme. As was expected for aerobic exercise, high-density lipoprotein-cholesterol (HDL-C) and HDL 3 -C levels were significantly increased in the sportsmen ( P < 0.05). Total plasma antioxidant capacity was 25...

...), heart rate fell from 63 to 52 beats/min ( P < 0.0001) and blood pressure fell from 116/74 to 113/69 mmHg ( P < 0.005); high-density lipoprotein (HDL)-cholesterol fell from 1.26 to 1.11 mmol/l ( P = 0.005), there being no change in the ratio of free to esterified cholesterol in HDL...

...Juan B. De Sanctis; Isaac Blanca; Nicholas E. Bianco 1. T lymphocytes and large granular lymphocytes internalized chylomicrons, very low-density lipoprotein, low-density lipoprotein, high-density lipoprotein and acetyl modified low-density lipoprotein through different receptors as assessed by flow...

...T. R. Gamlen; E. Layward; F. McTaggart; D. P. R. Muller 1. Significant positive correlations were found between the lipoprotein lipase and hepatic lipase activities of post-heparin plasma samples and plasma high-density-lipoprotein (HDL) cholesterol concentrations in 21 children...

...S. N. Rao; P. J. Magill; N. E. Miller; B. Lewis 1. The metabolism of the major proteins of plasma high-density lipoprotein (HDL), apoproteins AI and AII, have been studied in 10 normotriglyceridaemic subjects and in 11 hypertriglyceridaemic subjects (plasma triglyceride 4.5–25 mmol/l) by kinetic...

...G. J. Miller; N. E. Miller; M. T. Ashcroft 1. The relation between plasma high-density lipoprotein (HDL) cholesterol concentration and multiple coronary-risk factor status has been assessed in fifty-two middle-aged clinically healthy men from urban and rural Jamaica. 2. Rural hill-farmers had...