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Keywords: high-fat diet
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Clin Sci (Lond) (2018) 132 (8): 883–899.
Published: 30 April 2018
..., has been proposed to exert anti-apoptotic effects and to attenuate diabetes-related cardiac injuries. However, the role of CTRP3 in high-fat diet (HFD)-induced spermatogenic impairment remains unclear. In the present study, we fed male mice an HFD for 24 weeks to induce obesity. The expression...
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Clin Sci (Lond) (2017) 131 (15): 1989–2005.
Published: 13 July 2017
...) or a high-fat diet (HFD) for 14 weeks. One group of HFD mice was additionally exposed to telmisartan (3 mg/kg per day) for the last 4 weeks. HFD led to aortic outward remodeling, characterized by increased proteolysis, along with structural changes, such as fragmentation of elastic fibers and decreased...
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Clin Sci (Lond) (2015) 129 (12): 1025–1036.
Published: 18 September 2015
... and metabolic insulin resistance. We assessed insulin responses in all arterial segments, including aorta, distal saphenous artery and the microvasculature, as well as the metabolic insulin responses in muscle in rats fed on a high-fat diet (HFD) for various durations ranging from 3 days to 4 weeks...
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Clin Sci (Lond) (2012) 123 (9): 545–546.
Published: 13 July 2012
... Journal compilation © 2012 Biochemical Society 2012 apoptosis high-fat diet inflammation insulin resistance obesity tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) Type 2 diabetes mellitus Obesity has reached epidemic proportions worldwide. Obesity is an increasingly...
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Clin Sci (Lond) (2007) 113 (10): 397–399.
Published: 12 October 2007
...; 21.76 kJ/g (5.2 kcal/g)] and high-fat and carbohydrate-free [75%/0% of energy as fat/carbohydrate; 24.69 kJ/g (5.9 kcal/g)] diets, the high-fat diets containing carbohydrates were both obesogenic and diabetogenic, whereas the very-high-fat and carbohydrate-free diet was not obesogenic but led to insulin...
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Clin Sci (Lond) (2002) 103 (s2002): 13S–15S.
Published: 01 September 2002
... on a high-fat diet for 30 weeks, and of control mice. A subgroup of obese animals was also treated with the ET A receptor antagonist darusentan (50mg·kg -1 ·day -1 ). In vascular rings from control animals, acetylcholine caused endothelium-dependent contractions in the carotid artery, but not in the aorta...