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Clin Sci (Lond) (2017) 131 (4): 329–342.
Published: 03 February 2017
... cardiovascular drug genetic variation genome hormone sex In the blockbuster one-dose-fits-all drug model, trials have been large enough to show statistically significant responses in the complete sample, without considering which participants will benefit from the drug or not. In many instances...
Clin Sci (Lond) (2012) 122 (9): 429–437.
Published: 16 January 2012
...-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. adenomedullin 5 haemodynamics heart failure hormone renal function The AMs (adrenomedullins) are a group of regulatory peptides belonging to the CGRP (calcitonin gene-related peptide...
Clin Sci (Lond) (2009) 117 (6): 209–228.
Published: 14 August 2009
... activity in approx. 80% of patients with advanced disease, but most tumours relapse within 2 years to an incurable hormone-resistant state. Even for patients with early disease at the time of diagnosis, a proportion of patients will unfortunately develop relapsed disease following radical therapy...
Clin Sci (Lond) (2008) 114 (10): 635–642.
Published: 14 April 2008
... improvements in haemodynamics, hormonal profile and renal function than achieved by captopril alone. These results indicate that dual treatment with these two agents is beneficial. Correspondence: Dr Miriam T. Rademaker (email email@example.com ). 15 10 2007 26 11 2007 5 12...
Denzil GILL, Timothy SEIDLER, Richard W. TROUGHTON, Timothy G. YANDLE, Christopher M. FRAMPTON, Mark RICHARDS, John G. LAINCHBURY, Gary NICHOLLS
Clin Sci (Lond) (2004) 106 (2): 135–139.
Published: 01 February 2004
... 2003 15 9 2003 © 2004 The Biochemical Society 2004 creatine kinase hormone myocardial infarction myoglobin natriuretic peptide troponin Clinical Science (2004) 106, 135 139 (Printed in Great Britain) 135 Vigorous response in plasma N-terminal pro-brain natriuretic peptide (NT...
Clin Sci (Lond) (2002) 103 (s2002): 336S–339S.
Published: 01 September 2002
...Claudia HÖHNE; Roland C.E. FRANCIS; Gabriele KACZMARCZYK; Willehad BOEMKE This study compares the haemodynamic and hormonal responses during haemorrhage of conscious dogs pre-treated with an endothelin-A (ET-A) receptor inhibitor. The dogs were studied in two different randomized groups: the...
Atsuyuki WADA, Masato OHNISHI, Takayoshi TSUTAMOTO, Masanori FUJII, Takehiro MATSUMOTO, Takashi YAMAMOTO, Xinwen WANG, Masahiko KINOSHITA
Clin Sci (Lond) (2002) 103 (s2002): 254S–257S.
Published: 01 September 2002
... development of congestive heart failure (CHF). The selective enzymic inhibition of ET-1 formation thus seems to be a very important target in the prevention of CHF. We evaluated the chronic effects of a specific ECE inhibitor, FR901533 (0.3mg·kg -1 ·h -1 , n = 5) on cardiac, hormonal, and body fluid balance...
Maria J. PASCUAL, Maria A. SERRANO, Mohamad Y. EL-MIR, Rocio I.R. MACIAS, Felipe JIMÉNEZ, Jose J.G. MARIN
Clin Sci (Lond) (2002) 102 (5): 587–593.
Published: 22 April 2002
... gestation hormone steroid 587Clinical Science (2002) 102, 587 593 (Printed in Great Britain) Relationship between asymptomatic hypercholanaemia of pregnancy and progesterone metabolism Maria J. PASCUAL*, Maria A. SERRANO , Mohamad Y. EL-MIR , Rocio I. R. MACIAS , Felipe JIME; NEZ* and Jose J. G. MARIN...