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Keywords: hydrochlorothiazide
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Articles
Clin Sci (Lond) (1990) 78 (3): 321–325.
Published: 01 March 1990
...-established hypocalciuric action of hydrochlorothiazide, we have evaluated the effect of 15 days' treatment with hydrochlorothiazide in 10 hypercalciuric male stone-formers on urinary Ca 2+ and prostaglandin E 2 , as well as on plasma bicyclo-prostaglandin E 2 , 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D...
Articles
Clin Sci (Lond) (1986) 70 (4): 379–387.
Published: 01 April 1986
...S. J. Walter; D. G. Shirley 1. Hydrochlorothiazide was administered at two doses to Long-Evans rats for 7–10 days. Both doses resulted in an initial natriuresis and diuresis. After 1 day of treatment the natriuresis abated, but the diuresis persisted. 2. The mechanisms responsible for these chronic...
Articles
Clin Sci (Lond) (1984) 66 (6): 709–715.
Published: 01 June 1984
...L. Monnens; A. Jonkman; C. Thomas 1. Four boys with classical nephrogenic diabetes insipidus have been treated by indomethacin, by hydrochlorothiazide, and by the combination of indomethacin and hydrochlorothiazide. 2. Hydrochlorothiazide treatment was slightly more effective than indomethacin...
Articles
Clin Sci (Lond) (1982) 63 (6): 533–538.
Published: 01 December 1982
...D. G. Shirley; S. J. Walter; J. F. Laycock 1. Brattleboro rats with hereditary diabetes insipidus were maintained in metabolism cages for 12–14 days. During the final 5–7 days hydrochlorothiazide was added to the food of half the animals, resulting in a sustained antidiuresis. At the end...
Articles
Clin Sci (Lond) (1982) 63 (6): 525–532.
Published: 01 December 1982
...S. J. Walter; J. Skinner; J. F. Laycock; D. G. Shirley 1. The antidiuretic effect of hydrochlorothiazide in diabetes insipidus was investigated in rats with the hereditary hypothalamic form of the disease (Brattleboro rats). 2. Administration of hydrochlorothiazide in the food resulted in a marked...
Articles
Articles
Clin Sci (Lond) (1982) 63 (s8): 455s–458s.
Published: 01 October 1982
...Bonita Falkner; Gaddo Onesti; Melton B. Affrime; David T. Lowenthal 1. The effects of clonidine and hydrochlorothiazide on the cardiovascular responses to mental stess were compared in 29 adolescents with essential hypertension. 2. Clonidine therapy was associated with lower diastolic pressures...
Articles
Clin Sci (Lond) (1982) 63 (s8): 129s–132s.
Published: 01 October 1982
... well. CBI was more effective than hydrochlorothiazide, which at 2.2 mg/100 g body wt. daily only lowered the SBP to 167 ± 5 mmHg. The combined administration of CBI and hydrochlorothiazide produced an additive effect in that the SBP was reduced to 126 ± 4 mmHg. 4. CBI treatment resulted in a 36% and 11...
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Articles
Clin Sci (Lond) (1979) 57 (s5): 359s–362s.
Published: 01 December 1979
...P. Van Brummelen; A. Man In 't Veld; M. A. D. H. Schalekamp 1. Blood pressure, systemic haemodynamics, plasma volume, renin and aldosterone were measured during placebo treatment and after 1, 4 and 12 weeks of hydrochlorothiazide in 13 patients with uncomplicated essential hypertension. Nine...
Articles
Clin Sci (Lond) (1979) 57 (s5): 367s–369s.
Published: 01 December 1979
...A. Lechi; G. Covi; G. Danti; A. Dalla Riva; E. Pedrolli; S. Pomari 1. Tienilic acid and hydrochlorothiazide were evaluated in a double-blind trial in order to investigate their antihypertensive and metabolic effects. 2. After 5 weeks, the decreases in blood pressure and the changes in plasma...
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Articles
Clin Sci (Lond) (1979) 57 (5): 427–434.
Published: 01 November 1979
...S. J. Walter; J. F. Laycock; D. G. Shirley 1. Renal function in anaesthetized Brattleboro rats with hereditary hypothalamic diabetes insipidus was studied with micropuncture techniques before, and 1–3 h after, a single injection of hydrochlorothiazide. 2. In rats given hydrochlorothiazide and kept...
Articles
Clin Sci (Lond) (1979) 56 (5): 463–469.
Published: 01 May 1979
...P. Van Brummelen; M. Woerlee; M. A. D. H. Schalekamp 1. Renal blood flow, glomerular filtration rate, renal vascular resistance and filtration fraction were studied in ten patients with essential hypertension, during placebo, and after 1 week, 3, 6 and 9 months of hydrochlorothiazide. Plasma renin...
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Articles
Clin Sci Mol Med (1978) 55 (s4): 353s–354s.
Published: 01 December 1978
... The Biochemical Society and the Medical Research Society 1978 amiloride epidemiology hydrochlorothiazide hypertension methyldopa timolol Clinical Science and Molecular Medicine (1978) 55,353s-354s Results of a national therapeutic trial conducted in 10 000 hypertensive patients by 2000 general...
Articles
Clin Sci Mol Med (1978) 54 (3): 209–215.
Published: 01 March 1978
...D. G. Shirley; S. J. Walter; J. F. Laycock 1. The mechanism of the antidiuretic effect of hydrochlorothiazide in diabetes insipidus was studied in anaesthetized Brattleboro rats with the hereditary hypothalamic form of the disease. 2. The antidiuresis caused by acute administration...
Articles
Clin Sci Mol Med (1975) 48 (2): 147–151.
Published: 01 February 1975
...C. S. Sweet; M. Mandradjieff 1. Renal hypertensive dogs were treated with hydrochlorothiazide (8−2 μmol/kg or 33 μmol/kg daily for 7 days), or timolol (4.6 μmol/kg daily for 4 days), a potent β-adrenergic blocking agent, or combinations of these drugs). Changes in mean arterial blood pressure...
Articles
Clin Sci Mol Med (1973) 45 (s1): 199s–203s.
Published: 01 August 1973
...P. Lund-Johansen 1. The effects of hypotensive therapy with three separate diuretics, methyldopa and clonidine were separately assessed. 2. All the treated groups showed a significant drop in blood pressure. 3. Polythiazide and hydrochlorothiazide each produced a significant fall in total...