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Keywords: hyperfiltration
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Clin Sci (Lond) (2019) 133 (13): 1475–1486.
Published: 15 July 2019
...Malgorzata Kasztan; David M. Pollock Hyperfiltration, highly prevalent early in sickle cell disease (SCD), is in part driven by an increase in ultrafiltration coefficient (K f ). The increase in K f may be due to enlarged filtration surface area and/or increased glomerular permeability (P alb...
Clin Sci (Lond) (2018) 132 (13): 1453–1470.
Published: 18 July 2018
... hyperfiltration, coincident with the onset of neurodegeneration. Angiotensin converting enzyme inhibition had no effect on glomerular filtration rate of Uchl1 -/- mice indicating that the renin–angiotensin system does not contribute to the observed hyperfiltration. DCE-MRI revealed increased cortical renal blood...
Includes: Supplementary data