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Keywords: hyperhomocysteinaemia
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Articles
Homocysteine facilitates LOX-1 activation and endothelial death through the PKCβ and SIRT1/HSF1 mechanism: relevance to human hyperhomocysteinaemia
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2015) 129 (6): 477–487.
Published: 22 June 2015
...Ching-Hsia Hung; Shih-Hung Chan; Pei-Ming Chu; Kun-Ling Tsai HHcy (hyperhomocysteinaemia) is one of the major risk factors for cardiovascular diseases. A high concentration of Hcy (homocysteine) induces endothelial dysfunction by activating endothelial oxidative stress. LOX-1 (lectin-like oxidized...
Articles
Countervailing vascular effects of rosiglitazone in high cardiovascular risk mice: role of oxidative stress and PRMT-1
Available to PurchaseCarmine Savoia, Talin Ebrahimian, Catherine A. Lemarié, Pierre Paradis, Marc Iglarz, Farhad Amiri, Danesh Javeshgani, Ernesto L. Schiffrin
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (9): 583–592.
Published: 09 February 2010
... at −80 °C until analysis. A total of 20 μl of plasma, as per the manufacturer's instructions, was analysed by an ELISA-based kit (DLD Diagnostika). asymmetric ω- N G N G -dimethylarginine (ADMA) atherosclerosis endothelium hyperhomocysteinaemia peroxisome-proliferator-activated receptor...
Articles
Effects of acute methionine loading and vitamin Con endogenous fibrinolysis, endothelium-dependent vasomotion and platelet aggregation
Available to PurchaseCatherine LABINJOH, David E. NEWBY, Ian B. WILKINSON, Ian L. MEGSON, Helen MACCALLUM, Vanessa MELVILLE, Nicholas A. BOON, David J. WEBB
Journal:
Clinical Science
Clin Sci (Lond) (2001) 100 (2): 127–135.
Published: 19 December 2000
.... We conclude that, in the absence of alterations in endothelium-dependent vasomotion or platelet aggregation, substance P-induced t-PA release is enhanced following methionine loading. This suggests that the acute endogenous fibrinolytic capacity is augmented during acute hyperhomocysteinaemia...
Articles
Role of aminothiols as a component of the plasma antioxidant system and relevance to homocysteine-mediated vascular disease
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2001) 100 (1): 73–79.
Published: 13 December 2000
...Stuart J. MOAT; James R. BONHAM; Hilary J. POWERS Hyperhomocysteinaemia is considered to be an independent risk factor for vascular disease. Elevated plasma homocysteine may pose an oxidative stress, leading to the development of vascular damage. A component of this effect may be a disturbance...