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Keywords: hypothalamus
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Articles
Clin Sci (Lond) (2017) 131 (3): 211–223.
Published: 05 January 2017
... central nervous system (CNS) in general, and the hypothalamus in particular, are intricately involved in the development and maintenance of hypertension. Over the last several decades, the understanding of the brain's role in the development of hypertension has dramatically increased. This brief review is...
Articles
Clin Sci (Lond) (2016) 130 (19): 1697–1709.
Published: 23 August 2016
... (AMPK) has been revealed as one of the key molecules modulating energy homoeostasis. Indeed, AMPK appears to be essential for translating nutritional and energy requirements into generation of an adequate neuronal response, particularly in two areas of the brain, the hypothalamus and the hindbrain...
Articles
Clin Sci (Lond) (2013) 124 (4): 231–241.
Published: 31 October 2012
...Priya Sumithran; Joseph Proietto Although weight loss can usually be achieved by restricting food intake, the majority of dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the gastrointestinal tract, adipose tissue and other peripheral sites are integrated to...
Articles
Clin Sci (Lond) (2008) 114 (3): 183–193.
Published: 08 January 2008
... addition, alteration of AMPK signalling in the hypothalamus, which may function as a sensor of nutrient availability, integrating multiple nutritional and hormonal signals, may have a key role in the appearance of the MS. Correspondence: Professor Ángel Gil (email agil@ugr.es ). 2 4 2007...
Articles
Clin Sci (Lond) (2006) 110 (2): 143–152.
Published: 17 January 2006
... 2005 18 8 2005 19 9 2005 The Biochemical Society 2006 adiponectin adipose tissue hypothalamus leptin neuropeptide resistin The rising incidence of obesity, diabetes and other associated diseases has focused attention on the biology of adipose tissue. WAT (white...
Articles
Clin Sci (Lond) (2002) 103 (s2002): 162S–166S.
Published: 01 September 2002
... glutamatergic receptors hypothalamus Long Evans rats posterior pituitary supraoptic nucleus vasopressin 162S Clinical Science (2002) 103 (Suppl. 48), 162S 166S (Printed in Great Britain) Modulation of ETB receptor-induced arginine- vasopressin secretion by N-methyl-D-aspartate (NMDA) and c-aminobutyric...
Articles
Clin Sci (Lond) (1995) 89 (5): 543–548.
Published: 01 November 1995
... Society 1995 26 5 1995 29 6 1995 glucose metabolism hypothalamus insulin neuropeptide Y Clinical Science (1995) 89. 543-548 (Printed in Great Britain) Acute effects of central neuropeptide Y injection on glucose metabolism in fasted rats J. P. H.WILDING, Y. T. KRUSZYNSKA, P. D...
Articles
Clin Sci (Lond) (1993) 85 (4): 385–388.
Published: 01 October 1993
... sequence may therefore play an important role in the maintenance of vascular tone. 5 7 1993 21 7 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 amylin calcitonin calcitonin-gene-related peptide hypothalamus islet amyloid polypeptide lung receptor...
Articles
Clin Sci (Lond) (1991) 81 (3): 313–317.
Published: 01 September 1991
... explain the decreased febrile responses observed. 6 3 1991 21 3 1991 © 1991 The Biochemical Society and the Medical Research Society 1991 fever hypothalamus prostaglandin E 2 ChicalScience(l991) 81, 313-317 313 Effect of age on hypothalamic prostaglandin E, production and...
Articles
Clin Sci (Lond) (1991) 80 (5): 419–426.
Published: 01 May 1991
... any peptide differences between obese and lean rats might be due to the overweight condition per se , separate groups of obese rats were food-restricted to reduce their body weight to lean values. 2. Concentrations of neuromedin B, a bombesin-like peptide, in the central hypothalamus were...
Articles
Clin Sci (Lond) (1991) 80 (1): 59–64.
Published: 01 January 1991
... 1990 2 8 1990 © 1991 The Biochemical Society and the Medical Research Society 1991 gastric mucosal injury 5-hydroxytryptamine hypothalamus vagal adrenergic stimulation vasoconstriction Clinical Science (1991) 80,59-64 59 Mechanism of reserpine-induced acute gastric mucosal...
Articles
Clin Sci (Lond) (1987) 72 (5): 621–627.
Published: 01 May 1987
... females with methimazole in the drinking water. In two groups goitrpgen treatment continued for 3 or 10 weeks postnatally. 3. Methimazole treatment in utero did not produce significant changes in noradrenaline, dopamine or tyrosine content in either the hypothalamus or striatum. 4. Three weeks' postnatal...
Articles
Clin Sci (Lond) (1982) 63 (s8): 339s–342s.
Published: 01 October 1982
.... These observations lend support to the hypothesis that sodium and the sympathetic nervous system have synergistic effects in the pathogenesis of hypertension in the SHR. © 1982 The Biochemical Society and the Medical Research Society 1982 central noradrenergic activity hypothalamus...
Articles
Clin Sci (Lond) (1981) 61 (s7): 49s–51s.
Published: 01 December 1981
.... © 1981 The Biochemical Society and the Medical Research Society 1981 brain lesions hypothalamus salt hypertension sodium metabolism CIinicalScience (1981) 61,49s-51s 49 s Paraventricular-suprachiasmatic lesions prevent salt-induced hypertension in Dahl rats S I L V I A A Z A R , P. E R N S B...
Articles
Clin Sci (Lond) (1980) 59 (s6): 247s–249s.
Published: 01 December 1980
...I. Kobrin; R. Ebstein; D. Ben-Ishay 1. The noradrenaline-induced accumulation of cyclic AMP is decreased in both the anterior and the posterior hypothalamus of hypertension-prone as compared with resistant rats, but is similar in the cortex. 2. The nonadrenaline-induced accumulation of cyclic AMP...
Articles
Clin Sci (Lond) (1980) 59 (s6): 57s–60s.
Published: 01 December 1980
...M. M. Kilcoyne; D. L. Hoffman; E. A. Zimmerman 1. By immunoperoxidase technique, immunoreactive angiotensin II (ANG II) was located in the cell bodies of many magnocellular neurons in the supraoptic and paraventricular nuclei of the hypothalamus and their pathways to median eminence and posterior...
Articles
Clin Sci (Lond) (1980) 59 (s6): 397s–399s.
Published: 01 December 1980
... in men. © 1980 The Biochemical Society and the Medical Research Society 1980 haemodynamics hypothalamus obesity plasma volume Clinical Science (1980) 59,397s-399s 397s Haemodynamic changes associated with obesity and high blood pressure in rats with ventromedial hypothalamic lesions E...
Articles
Clin Sci (Lond) (1980) 59 (s6): 263s–265s.
Published: 01 December 1980
... adrenaline than resistant rats. 3. In response to a high salt diet brain-stem noradrenaline increased in sensitive rats and resistant rats exhibited a decrease on the same diet. © 1980 The Biochemical Society and the Medical Research Society 1980 brain stem catecholamines hypothalamus salt...
Articles
Clin Sci (Lond) (1979) 57 (s5): 205s–208s.
Published: 01 December 1979
...G. Stock; H. Stumpf; K. H. Schlör 1. Stimulation of the central amygdala, posterolateral hypothalamus and locus coeruleus in cats resulted in a sustained increase in arterial pressure, an increase in heart rate, with a poststimulation bradycardia and an increase in peripheral resistance...
Articles
Clin Sci (Lond) (1979) 57 (s5): 111s–113s.
Published: 01 December 1979
... to adult levels. Peak numbers of receptors were up to 10 times the adult numbers. 3. The midbrain and thalamus-hypothalamus had maximum numbers of angiotensin II receptors at 2 weeks of age, whereas the rest of the brain regions had maximum numbers at 1 week. 4. Saralasin-infusion experiments...
Articles
Clin Sci Mol Med (1976) 51 (s3): 395s–397s.
Published: 01 December 1976
...M. Iijima; Y. Kitamura; N. Yamamoto; H. Kawamura; T. Yasugi; M. Hatano 1. Intravenous administration of angiotensin II reduced the adrenaline content, increased the catechol- O -methyltransferase activity, and decreased the monoamine oxidase activity of the rat hypothalamus. 2. Intraventricularly...
Articles
Clin Sci Mol Med (1975) 48 (s2): 277s–278s.
Published: 01 January 1975
...H. Struyker Boudier; G. Smeets; G. Brouwer; J. Van Rossum 1. Various drugs were injected stereotactically into the brain of anaesthetized rats. 2. Noradrenaline injected into the area of the nucleus of the tractus solitarius in the lower brain stem or into the far anterior hypothalamus/pre-optic...
Articles
Clin Sci Mol Med (1975) 48 (s2): 215s–223s.
Published: 01 January 1975
... pathological significance of the neural control of renin release has been discussed. © 1975 The Biochemical Society and the Medical Research Society 1975 aortic stenosis diuretics hypothalamus orthostasis renin sympathetic system Clinical Science and Molecular Medicine (1975) 48,215s-223s...
Articles
Clin Sci Mol Med (1975) 48 (s2): 191s–194s.
Published: 01 January 1975
...A. Philippu 1. Cats were anaesthetized with pentobarbitone sodium. The hypothalamus was superfused with drugs through a push-pull cannula and electrically stimulated with the non-insulated tip of the cannula. In another series of experiments, the hypothalamus was stimulated with a monopolar...