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Mahmoud SALMAN, Georgios K. GLANTZOUNIS, Wenxuan YANG, Fiona MYINT, George HAMILTON, Alexander M. SEIFALIAN
Clin Sci (Lond) (2005) 108 (2): 159–165.
Published: 21 January 2005
..., skeletal muscle oxygenation was measured using a new Clark-type TC P O 2 [transcutaneous P O 2 (partial pressure of O 2 )]/ P CO 2 (partial pressure of CO 2 ) monitoring system and optical NIRS (near-infrared spectroscopy) at graded levels of hypoxaemia using a rabbit model ( n =6). The TC P O 2 / P CO 2...
Clin Sci (Lond) (2004) 106 (1): 43–51.
Published: 01 January 2004
... serum EPO levels were serially measured. Initial mean EPO levels were slightly above the normal range (41.4±83.5 units/l), but in the majority of patients the initial EPO levels were significantly reduced. Following the correction of hypoxaemia, mean EPO levels decreased to 14.1±16.9 units/l ( P =0.0093...
Muneo YOSHIBAYASHI, Tetsuro KAMIYA, Toshio NISHIKIMI, Yoshihiko SAITO, Hisayuki MATSUO, Kenji KANGAWA
Clin Sci (Lond) (1999) 96 (6): 543–547.
Published: 20 April 1999
... of the pulmonary circulation and the pathophysiology of hypoxaemia. The aim of the present study was to investigate the pathophysiological significance of adrenomedullin in hypoxaemia caused by congenital cyanotic heart disease. Subjects were 16 patients with congenital cyanotic heart disease aged 0.8–10 years...
Clin Sci (Lond) (1998) 94 (3): 279–286.
Published: 01 March 1998
... the phosphocreatine level and pH value. Under both conditions of oxygen availability, the magnitude of metabolic changes remained similar and the duration of contraction was unaffected (similar workload). However, hypoxaemia significantly reduced the rate of changes in integrated surface electromyogram activity...
Clin Sci (Lond) (1995) 89 (2): 165–169.
Published: 01 August 1995
...Robert I. Cargill; David G. Kiely; Brian J. Lipworth 1. Abnormalities of myocardial relaxation may occur as a consequence of myocyte hypoxia. We have therefore examined the effects of hypoxaemia on right and left ventricular diastolic function in 10 healthy male subjects. 2. After resting to reach...
Michael F. Fitzpatrick, Tom MacKay, Kenneth F. Whyte, Martin Allen, Robert C. Tam, Caroline J. Dore, Michael Henley, P. Mary Cotes, Neil J. Douglas
Clin Sci (Lond) (1993) 84 (3): 319–324.
Published: 01 March 1993
... with the highest mean deviation from the geometric mean at 22.00 hours and the nadir at 05.00 hours. 3. The three patients with chronic obstructive pulmonary disease with the most marked nocturnal desaturation (lowest arterial oxygen saturation <57%) and most marked daytime hypoxaemia (daytime arterial partial...
Clin Sci (Lond) (1993) 84 (3): 325–329.
Published: 01 March 1993
... at the mouth over the range 6–26 Hz during tidal breathing. Six normal subjects (mean age, 27.3 years; forced expiratory volume in 1 s, 3.82 litres) and 18 patients with severe chronic obstructive pulmonary disease and hypoxaemia (mean age, 66.6 years; forced expiratory volume in 1 s, 0.61 litres; O 2...
Chim C. Lang, Wendy J. Coutie, Allan D. Struthers, D. Paul Dhillon, John H. Winter, Brian J. Lipworth
Clin Sci (Lond) (1992) 83 (5): 529–533.
Published: 01 November 1992
... of hypoxaemia. Further studies are required to investigate the release and clearance of brain natriuretic peptide in chronic obstructive pulmonary disease, as well as its pulmonary vasodilator activity in vivo. 6 7 1992 9 7 1992 © 1992 The Biochemical Society and the Medical Research Society...
Clin Sci (Lond) (1987) 72 (6): 693–698.
Published: 01 June 1987
... oxygen, significant at the 8% level. 4. The reduction in breathlessness produced by preventing exercise desaturation cannot be explained by the decrease in ventilation. This suggests that hypoxia may be a stimulus for breathlessness. The mechanism is unknown. breathlessness exercise hypoxaemia...
Clin Sci (Lond) (1984) 67 (5): 515–519.
Published: 01 November 1984
...C. R. Swinburn; J. M. Wakefield; P. W. Jones 1. We have examined the hypothesis that hypoxaemia contributes to breathlessness by a mechanism distinct from its action as a ventilatory stimulant. 2. Five patients who developed arterial oxygen desaturation during incremental exercise were studied...
Clin Sci (Lond) (1979) 57 (5): 389–396.
Published: 01 November 1979
... asthma chronic hypercapnia hypoxaemia oxygen breathing oxygen transients respiratory failure ventilation-perfusion ratios Clinical Science (1979) 51,389-396 Changes in arterial blood gases during and after a period of oxygen breathing in patients with chronic hypercapnic respiratory failure...
Clin Sci Mol Med (1977) 53 (4): 401–404.
Published: 01 October 1977
...P. H. Baylis; R. A. Stockley; D. A. Heath 1. Acute hypoxaemia has been reported to stimulate vasopressin release in animals. 2. Hypoxaemia induced by breathing 9·3% oxygen for 15–20 min failed to produce a rise in plasma arginine vasopressin concentration in six out of eight healthy human subjects...
Clin Sci Mol Med (1976) 50 (2): 109–114.
Published: 01 February 1976
... the oxygen breath tests in any patient. 22 9 1975 © 1976 The Biochemical Society and the Medical Research Society 1976 hypoxaemia oxygen tests peripheral chemoreceptors pulmonary infiltration respiratory drive ventilation Clinical Science and Molecular Medicine (1976) 50,109-1 14...
Clin Sci Mol Med (1974) 46 (3): 347–356.
Published: 01 March 1974
... the fraction measured was an important part of the overall efferent drive to the respiratory muscles. 24 8 1973 © 1974 The Biochemical Society and the Medical Research Society 1974 peripheral chemoreceptors hypoxaemia chronic bronchitis oxygen tests respiratory drive ventilation...
Clin Sci Mol Med (1973) 44 (6): 563–570.
Published: 01 June 1973
...B. D. W. Harrison 1. The relationship between hypoxaemia, as measured by arterial blood oxygen saturation, and red cell volume is reported in nineteen patients with chronic airways obstruction and raised peripheral venous haematocrit. 2. These patients showed an increase in red cell mass response...
Clin Sci (1972) 42 (5): 555–565.
Published: 01 May 1972
... and systemic vascular resistance decreased during hypoxaemia in all subjects. Although the initial cardiac output was lower with increasing age, the change during hypoxaemia correlated poorly with age. 3. Forearm blood flow increased with age and the change produced by hypoxaemia was also related to the age...