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Keywords: ibuprofen
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Articles

Celecoxib modifies glomerular basement membrane, mesangium and podocytes in OVE26 mice, but ibuprofen is more detrimental

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Rania Nasrallah, Susan J. Robertson, Jacob Karsh, Richard L. Hébert
Journal: Clinical Science
Clin Sci (Lond) (2013) 124 (11): 685–694.
https://doi.org/10.1042/CS20120543
Published: 15 February 2013
... cardiovascular outcomes in susceptible individuals. Given the renal controversies concerning COX-2 inhibitors, we compared the effect of chronic NSAIDs (non-selective, ibuprofen; COX-2-selective, celecoxib) on diabetic kidneys in OVE26 mice from 8 weeks of age. Systolic BPs (blood pressures) were increased...
View articletitled, Celecoxib modifies glomerular basement membrane, mesangium and podocytes in OVE26 mice, but ibuprofen is more detrimental
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Articles

Inhibition of prostaglandin synthesis does not alter the decrease in pre-capillary resistance in the human calf in response to small cumulative increases in venous congestion

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Stephen I. Anderson, Margaret D. Brown
Journal: Clinical Science
Clin Sci (Lond) (2005) 109 (3): 303–309.
https://doi.org/10.1042/CS20050113
Published: 24 August 2005
... whether prostaglandins are involved in this local flow regulation by measuring calf blood flow and microvascular filtration capacity using strain gauge plethysmography in young male subjects before (baseline) and after taking either ibuprofen, an inhibitor of prostaglandin synthesis (1600 mg over 2 days...
View articletitled, Inhibition of prostaglandin synthesis does not alter the decrease in pre-capillary resistance in the human calf in response to small cumulative increases in venous congestion
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Articles

Assessment of Gentamicin—Induced Nephrotoxicity in Rats Treated with Low Doses of Ibuprofen and Diclofenac Sodium

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M. M. Farag, M. Mikhail, R. Shehata, E. Abdel-Meguid, S. Abdel-Tawab
Journal: Clinical Science
Clin Sci (Lond) (1996) 91 (2): 187–191.
https://doi.org/10.1042/cs0910187
Published: 01 August 1996
...M. M. Farag; M. Mikhail; R. Shehata; E. Abdel-Meguid; S. Abdel-Tawab 1. The effects of two non-steroidal anti-inflammatory drugs, ibuprofen (20 mg day −1 kg −1 ) and diclofenac sodium (2.5 mg day −1 kg −1 ), on the severity of gentamicin-induced nephrotoxicity were evaluated in rats. 2...
View articletitled, Assessment of Gentamicin—Induced Nephrotoxicity in Rats Treated with Low Doses of Ibuprofen and Diclofenac Sodium
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