...Marguerite Hatch; N. D. Vaziri 1. The potential contribution of enteric pathways to the extra-renal excretion of uric acid in chronic renal failure was evaluated by measuring [ 14 C]-urate and 36 Cl − transport in isolated, short-circuited segments of jejunum, ileum and distal colon from normal...

... reflexes. 2. We examined this hypothesis further by studying the influence of neuronal blockade on cholera toxin-induced changes in fluid transport across rabbit ileum in vitro. Mucosa, stripped of muscle layers, was mounted in flux chambers and luminal application of crude cholera toxin (2 μg/ml) caused...

...I. McL. Welch; C. Bruce; S. E. Hill; N. W. Read 1. Infusion of lipid into the ileum delays the transit of a meal through the stomach and small intestine and could therefore influence the rate and degree of nutrient absorption. 2. Experiments were carried out on human volunteers to investigate...

...I. W. Booth; P. J. Milla; J. T. Harries 1. The effects of MgCl 2 on the electrical characteristics and sodium and chloride transport in short-circuited rabbit terminal ileum in vitro were studied. 2. Increasing the magnesium concentration from a basal concentration of 1.1 mmol/l to either 2.5...

...R. M. Batt; G. Wells; T. J. Peters 1. Enterocytes, isolated from the proximal jejunum and distal ileum of normal and prednisolone-treated rats, were homogenized and fractionated by isopycnic centrifugation on sucrose density gradients. The distributions of marker enzymes for the principal...

...R. M. Batt; T. J. Peters 1. Enterocytes, isolated from the proximal jejunum and distal ileum of the rat, were homogenized and their organelles separated by isopycnic centrifugation on continuous sucrose density gradients. The distributions of marker enzymes for the principal organelles, RNA...

...R. M. Batt; T. J. Peters 1. The absorption in vivo of d-galactose by the rat small intestine has been examined in proximal jejunum and distal ileum by use of a recirculation—perfusion technique. 2. Multiple sequential perfusions over 4 h produced no subsequent functional or morphological damage...

...R. M. Batt; T. J. Peters 1. The effects in rats of an oral pharmacological dose of prednisolone on mucosal function, enzymology, lysosomal membrane fragility, morphology and cell kinetics have been examined in proximal jejunum and distal ileum. 2. The maximum absorptive capacity for galactose...

... in the human ileum. Variable iso-osmotic bulk flow was again encountered, but ion exchange was of a lower magnitude than in the jejunum or colon. Qualitatively, ion exchange in the ileum was intermediate between the jejunum and colon. 5. These analyses suggest that transmucosal bulk flow and ion exchange may...