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Keywords: imatinib
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Articles
Clin Sci (Lond) (2021) 135 (19): 2243–2263.
Published: 08 October 2021
...Andris Elksnis; Tomas A Schiffer; Fredrik Palm; Yun Wang; Jing Cen; Kyril Turpaev; Anongnad Ngamjariyawat; Shady Younis; Suling Huang; Yu Shen; Ying Leng; Peter Bergsten; Tony Karlsborn; Nils Welsh; Xuan Wang The protein tyrosine kinase inhibitor imatinib is used in the treatment of various...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2010) 118 (4): 241–247.
Published: 09 November 2009
...Dariush Mokhtari; Nils Welsh Altered tyrosine kinase signalling has been implicated in several diseases, paving the way for the development of small-molecule TKIs (tyrosine kinase inhibitors). TKIs such as imatinib, sunitinib and dasatinib are clinically used for treating chronic myeloid leukaemia...
Articles
Clin Sci (Lond) (2006) 111 (4): 233–249.
Published: 13 September 2006
..., is of major importance in the development of many haematological malignancies. An understanding of the mechanisms by which BCR - ABL contributes to the pathogenesis of chronic myeloid leukaemia led to the development of imatinib, the first of several tyrosine kinase inhibitors to enter clinical trials...