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Keywords: immune cells
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Clin Sci (Lond) (2023) 137 (24): 1823–1838.
Published: 21 December 2023
... and tubular atrophy (IFTA). Accordingly, proactive prevention of CAD requires a comprehensive understanding of the immune mechanisms associated with either further dysfunction or impaired repair. Allograft rejection is primed by innate immune cells and carried out by adaptive immune cells. The rejection...
Clin Sci (Lond) (2023) 137 (19): 1533–1545.
Published: 03 October 2023
... the phenotypic switching of vascular smooth muscle cells from a contractile to synthetic state during AAA. In addition, it was demonstrated that colchicine was able to reduce vascular inflammation, oxidative stress, cell pyroptosis and immune cells infiltration to the aortic wall in the AAA mice model. Finally...
Includes: Supplementary data
Clin Sci (Lond) (2022) 136 (10): 771–785.
Published: 27 May 2022
... irAEs, but the detailed mechanisms underlying irAEs remain largely unknown. Owing to the wide expression of IC molecules on distinct immune cell subpopulations and the fact that ICB agents generally affect IC-expressing cells, the influences of ICB agents on immune cells in irAEs need to be determined...
Clin Sci (Lond) (2009) 116 (11): 791–804.
Published: 01 May 2009
... on the regulation of inflammation within the vasculature during atherogenesis. We will concentrate on the different functions played by each isoform of PI3K in immune cells which could be involved in this pathology, raising the possibility that inhibition of one or more PI3K isoforms may represent an effective...