... of University College London in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC. hormones immune response mitochondria organ dysfunction sepsis stress response Sepsis is defined as a dysregulated host...

... and progression in CRC [ 45 ] © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 Colorectal cancer immune response molecular mechanisms Tumour budding Colorectal cancer (CRC) is the third most diagnosed cancer and the second most lethal...

... ]. This prevention is partially thought to be due to an early modulation of immune responses. If we can unravel the early immune pathogenic mechanism(s) involved in the development of PreE, there is potential for improved prevention. Human maternal plasma copeptin, a stable biomarker of arginine vasopressin (AVP...

... hyperresponsiveness (AHR) and inflammation are triggered following hMPV infection, and hMPV is able to persist in vivo by inhibiting innate immune responses and causing aberrant adaptive responses. In this review, we discuss the prevalence of hMPV infection in pediatric and adult populations and its potential role...

... is involved in HBV-related cellular immune responses. Cluster of differentiation (CD)4 + T-cells from peripheral blood were derived from healthy volunteers, resolved HBV individuals and chronic active hepatitis B patients and stimulated with CD3/28-conjugated beads. We analysed mRNA and protein levels of IL...

...Masahiko Mihara; Misato Hashizume; Hiroto Yoshida; Miho Suzuki; Masashi Shiina IL (interleukin)-6, which was originally identified as a B-cell differentiation factor, is a multifunctional cytokine that regulates the immune response, haemopoiesis, the acute phase response and inflammation. IL-6...

...Thais Martins de Lima; Renata Gorjão; Elaine Hatanaka; Maria Fernanda Cury-Boaventura; Erica Paula Portioli Silva; Joaquim Procopio; Rui Curi Fatty acids (FAs) have been shown to alter leucocyte function and thus to modulate inflammatory and immune responses. In this review, the effects of FAs...

... interact with several pathways in the host's immune response and disrupt pathogen-associated pattern recognition pathways, interfere with cellular immunoregulation via CD81 binding and subvert the activity of NK (natural killer) cells as well as CD4 + and CD8 + T-cells. Finally, HCV-specific T-cells become...

... anticancer immune responses, very few have reached mainstream clinical use. A new approach introduced over the last few years is to use immunostimulatory mAbs (monoclonal antibodies) to boost weak endogenous antitumour immune responses to levels which are therapeutic. Such agonistic or antagonistic mAbs bind...

... is associated with increased risk for the development of peptic ulcer disease, gastric adenocarcinoma and gastric lymphoma. The development of a sustained gastric inflammatory and immune response to infection appears to be pivotal for the development of disease. During its long co-existence with humans, H...

... arthroplasty catecholamines cortisol cytokines hormones immune response surgery 71Clinical Science (2000) 98, 71 79 (Printed in Great Britain) Hip and knee arthroplasty: a comparison and the endocrine, metabolic and inflammatory responses G. M. HALL*, D. PEERBHOY , A. SHENKIN , C. J. R. PARKER§ and P...