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Keywords: immunometabolism
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Clin Sci (Lond) (2024) 138 (8): 515–536.
Published: 23 April 2024
..., the metabolic and mitochondrial changes caused by obesity may contribute to the immunometabolic context that accelerates neurogenerative processes. The literature shows that chronic inflammation occurring from excessive fat accumulation and circulating hormone levels in obesity, and toxic protein aggregates...
Clin Sci (Lond) (2022) 136 (6): 435–454.
Published: 29 March 2022
...Maria J. Forteza; Daniel F.J. Ketelhuth Over the last decade, there has been a growing interest to understand the link between metabolism and the immune response in the context of metabolic diseases but also beyond, giving then birth to a new field of research. Termed ‘immunometabolism...
Clin Sci (Lond) (2021) 135 (11): 1389–1408.
Published: 04 June 2021
... is implicated in the pathogenesis of many human diseases, including allergy, chronic inflammation and cancer. In this review, we aim to introduce the reader to the field of cholesterol immunometabolism and discuss how both metabolites arising from the pathway and cholesterol homeostasis are able to impact...
Clin Sci (Lond) (2019) 133 (2): 195–203.
Published: 18 January 2019
..., similar to those induced by microbial products or high cholesterol diets in mice, may help to explain the chronic inflammatory state driving atherosclerosis and cardiovascular risk that exists for patients with diabetes despite improved metabolic control. From an immunometabolic perspective, we speculate...