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Keywords: immunometabolism
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Clin Sci (Lond) (2021) 135 (11): 1389–1408.
Published: 04 June 2021
... implicated in the pathogenesis of many human diseases, including allergy, chronic inflammation and cancer. In this review, we aim to introduce the reader to the field of cholesterol immunometabolism and discuss how both metabolites arising from the pathway and cholesterol homeostasis are able to impact...
Clin Sci (Lond) (2019) 133 (2): 195–203.
Published: 18 January 2019
... immunometabolic perspective, we speculate that changes supporting the trained macrophage phenotype, such as up-regulation of glycolysis, indicate that a high glucose environment could enhance the pro-inflammatory consequences of trained immunity thereby contributing to the accelerated progression of...